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LLYEli Lilly and CompanyBuy Wait6.4·$1116.20-0.61%
Buy WaitModerate Confidence
Investment thesis

Eli Lilly is a high-quality healthcare franchise with 56% revenue growth, a wide economic moat, and four consecutive double-digit earnings beats, but the stock has effectively reached the analyst consensus price target with only 0.9% headroom remaining — the setup favors accumulation on weakness rather than initiating at current levels.

Thesis pillars

  • Wide Moat Margin QualityStable
  • Consistent Earnings OutperformanceStable
  • Exceptional Revenue Growth TrajectoryStable
  • +1 more pillar — see the Why tab for full reasoning

Full reasoning →

Open full analysis

Eli Lilly and Company (LLY) Stock Analysis

Temporary headwind edge

Buy WaitVALUE-TRAP 1/5GrowthQualityModerate Confidence

Healthcare · Drug Manufacturers - General

Wait for pullback to $1087.92. At $1116.20 the A.R:R is 1.3:1 — below the 1.5:1 minimum for BUY_NOW. Engine's entry $1087.92 (1 ATR pullback) is the shallowest technical level that clears the 2:1 A.R:R minimum. Key risks: Thin upside margin: 6.4%; Leverage penalty (D/E 1.6): -1.0.

Eli Lilly discovers, develops, and markets human pharmaceutical products in a single business segment, with cardiometabolic health products (including Mounjaro, Zepbound, and Jardiance) and oncology (Verzenio) anchoring a portfolio sold in approximately 90 countries. Six... Read more

$1116.20+6.4% A.UpsideScore 6.4/10#2 of 16 Drug Manufacturers - General
QualityF-score7 / 9FCF yield1.11%
IncomeYield0.62%(5y avg 0.85%)Payout21.69%sustainable
Entry $1087.92(1 ATR pullback)Stop $1032.36Target $1186.80(analyst − 10%)A.R:R 1.3:1
Analyst target$1318.66+18.1%29 analysts
$1186.80our TP
$1116.20price
$1318.66mean
$930
$1600

Wait for pullback to $1087.92. At $1116.20 the A.R:R is 1.3:1 — below the 1.5:1 minimum for BUY_NOW. Engine's entry $1087.92 (1 ATR pullback) is the shallowest technical level that clears the 2:1 A.R:R minimum. Key risks: Thin upside margin: 6.4%; Leverage penalty (D/E 1.6): -1.0. Chart setup: No clear chart pattern; technical signals are mixed. Growth is cheap relative to earnings, but the technical setup has not yet produced a breakout above resistance (PEG 1.10, quality 8.3/10, growth 8.6/10). Score 6.4/10, moderate confidence.

Passes 6/8 gates (clean insider activity, no SEC red flags, news events none recent, earnings proximity 46d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum and favorable risk/reward ratio. Suitability: moderate.

10-K grounded · weekly refresh

About Eli Lilly and Company

About Eli Lilly and Company

Mounjaro and Zepbound, Eli Lilly's GLP-1/GIP-based incretin medicines for type 2 diabetes and obesity, together generated 56% of total revenues in 2025 — each individually exceeding $3 billion. Combined with Verzenio (breast cancer), Trulicity, Taltz, and Jardiance, the six highest-revenue products represented 82% of 2025 total revenues. Mounjaro and Zepbound carry U.S. compound patent protection through 2036, and products are sold in approximately 90 countries.

Eli Lilly sells prescription medicines through U.S. wholesale distributors — McKesson Corporation, Cencora, Inc., and Cardinal Health, Inc. — each of which accounts for a significant percentage of consolidated revenue; no other single customer exceeds 10%. Net revenue reflects rebates and discounts negotiated with pharmacy benefit managers and health plans; access to anti-obesity medicines faces particular friction because self-insured U.S. employers must generally opt in for obesity coverage, and payers in many international markets do not cover weight-loss indications. A growing share of U.S. sales flows through LillyDirect, the company's direct-to-patient platform launched to reduce formulary dependency. Jardiance and Basaglar are co-developed with Boehringer Ingelheim, while Tyvyt is commercialized in China with Innovent Biologics.

Show full overview

The Inflation Reduction Act's negotiation mechanism targets Lilly's portfolio directly: HHS selected Jardiance as one of the first ten medicines subject to government-set Medicare prices effective 2026, then in January 2026 selected Trulicity and Verzenio with government pricing effective 2028. Trulicity also faces U.S. compound patent expiry and biologics data protection loss in 2027, concentrating erosion risk within a two-year window. The 10-K notes the company expects additional products selected in future years, which would accelerate revenue erosion further.

See also: Healthcare · Drug Manufacturers - General

From Eli Lilly and Company's most recent 10-K filing, extracted June 11, 2026.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-09-13
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Oct 29, 202646d to earnings· next earnings call

Thesis

Rewards
V7 flight-to-quality bonus: +0.5 (Q=8.3 in RISK_OFF)
Sector modifier (Healthcare): +0.5
Strong earnings beat streak (4/4)
Risks
Thin upside margin: 6.4%
Leverage penalty (D/E 1.6): -1.0
Negative momentum

Key Metrics

P/E (TTM)37.5
P/E (Fwd)23.6
Mkt Cap$994.9B
EV/EBITDA24.9
Profit Mgn33.5%
ROE102.3%
Rev Growth47.7%
Beta0.50
Dividend0.62%
Rating analysts38

Quality Signals

Piotroski F7/9MoatWideCompounder

Options Flow

P/C1.26bearish
IV39%normal

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

Not investment advice. TrendMatrix is not a registered investment adviser. Our content is for informational and educational purposes only. Consult your own licensed investment adviser, broker, or tax professional before making any investment decision.

Conflicts and positions. The TrendMatrix editorial team frequently holds personal long-term positions in securities discussed. We disclose positions held at the time of publication on each piece. We maintain a trading-window policy: we do not initiate or close positions in the same direction as a TrendMatrix publication within 24 hours before or 72 hours after publication.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

1 floor-breaker·1 ceiling hit

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Obv
1.0
Volume
1.7
Ma Position
4.0
Rsi
9.8
Oversold in uptrend (RSI 2)Volume distribution (falling OBV)Above 200-day MA
GatesMomentum 3.3<4.5A.R:R 1.3 < 1.5@spotInsider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 46d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Moderate
RSI
2 · Oversold
20D MA 50D MA 200D MAGOLDEN CROSSSupport $1113.29Resistance $1292.65

Price Targets

$1032
$1088
$1187
A.Upside+6.4%
A.R:R1.3:1

Position Sizing

ConvictionHigh conviction
Suggested %0.9%
Max %1.8%
RegimeRisk-Off

Risk Alerts

! momentum at 3.3 (below the engine's 4.5 threshold)
! asymmetry at 1.3 (below the engine's 1.5 threshold)@spot

Earnings

B
B
B
B
4/4 beats
Next Earnings2026-10-29 (46d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is LLY stock a buy right now?

Wait for pullback to $1087.92. At $1116.20 the A.R:R is 1.3:1 — below the 1.5:1 minimum for BUY_NOW. Engine's entry $1087.92 (1 ATR pullback) is the shallowest technical level that clears the 2:1 A.R:R minimum. Key risks: Thin upside margin: 6.4%; Leverage penalty (D/E 1.6): -1.0. Chart setup: No clear chart pattern; technical signals are mixed. Growth is cheap relative to earnings, but the technical setup has not yet produced a breakout above resistance (PEG 1.10, quality 8.3/10, growth 8.6/10). Target $1186.80 (+6.3%), stop $1032.36 (−8.1%), A.R:R 1.3:1. Score 6.4/10, moderate confidence.

What is the LLY stock price target?

Take-profit target: $1186.80 (+6.4% upside). Target $1186.80 (+6.3%), stop $1032.36 (−8.1%), A.R:R 1.3:1. Stop-loss: $1032.36.

What are the risks of investing in LLY?

Thin upside margin: 6.4%; Leverage penalty (D/E 1.6): -1.0; Negative momentum.

Is LLY overvalued or undervalued?

Eli Lilly and Company trades at a P/E of 37.5 (forward 23.6). TrendMatrix value score: 4.3/10. Verdict: Buy (Wait for Entry).

What do analysts say about LLY?

38 analysts cover LLY with a consensus score of 4.1/5. Average price target: $1319.

What does Eli Lilly and Company do?Eli Lilly discovers, develops, and markets human pharmaceutical products in a single business segment, with...

Eli Lilly discovers, develops, and markets human pharmaceutical products in a single business segment, with cardiometabolic health products (including Mounjaro, Zepbound, and Jardiance) and oncology (Verzenio) anchoring a portfolio sold in approximately 90 countries. Six products each generated more than $3 billion in revenue in 2025, collectively representing 82% of total revenues, with GLP-1/GIP medicines Mounjaro and Zepbound alone at 56%.

Related stocks: BMY (Bristol-Myers Squibb Company) · AMGN (Amgen Inc.) · ABBV (AbbVie Inc.) · SNY (Sanofi) · AZN (AstraZeneca PLC)
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