Aurinia Pharmaceuticals Inc (AUPH) Stock Analysis
Breakout setup
Healthcare · Biotechnology
Wait for pullback to $15.25. BUY gates pass at $16.21, but cyclical risk: PE expanding 1.9x (earnings normalizing) and analyst target reached - limited upside remaining argue for a more patient entry. Engine's entry $15.25 (Support Atr Sticky) is the shallowest technical level that clears the 2:1 A.R:R minimum.
Aurinia Pharmaceuticals markets LUPKYNIS (voclosporin), the first FDA-approved oral therapy for adult lupus nephritis, generating $271.3 million in 2025 net product sales. Revenue comes from direct U.S. commercialization through specialty pharmacies and a supply and royalty... Read more
Wait for pullback to $15.25. BUY gates pass at $16.21, but cyclical risk: PE expanding 1.9x (earnings normalizing) and analyst target reached - limited upside remaining argue for a more patient entry. Engine's entry $15.25 (Support Atr Sticky) is the shallowest technical level that clears the 2:1 A.R:R minimum. Chart setup: Golden cross, above all MAs, RSI 62, MACD bullish. Fundamentals strong but target reached (-8.8% upside). Wait for pullback. Score 7.0/10, moderate confidence.
Passes 7/8 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, earnings proximity 42d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: aggressive.
About Aurinia Pharmaceuticals Inc
About Aurinia Pharmaceuticals Inc
LUPKYNIS (voclosporin), the only FDA-approved oral therapy for adult lupus nephritis, generated $271.3 million in net product sales for Aurinia Pharmaceuticals in 2025 — a 25% increase from $216.2 million in 2024 — with operating cash flows of $135.7 million, up 206% year over year. Aurinia commercializes LUPKYNIS directly in the United States and supplies product to Otsuka Pharmaceutical Co., Ltd. for Japan, the European Union, the United Kingdom, and Switzerland under a collaboration agreement signed in December 2020. The company held $398.0 million in cash, equivalents, and investments at December 31, 2025, and repurchased 12.2 million shares for $98.2 million during the year.
Aurinia sells LUPKYNIS in the U.S. through two specialty pharmacies and a specialty distributor, with payer coverage from commercial plans and government programs including Medicaid and Medicare. Outside the U.S., Otsuka has obtained regulatory approval in Japan, the EU, the UK, and Switzerland; Aurinia earns royalties of 10% to 20% on Otsuka Territory net sales. Manufacturing is entirely outsourced: Lonza is the sole supplier of voclosporin drug substance at a dedicated Monoplant facility, Catalent Pharma Solutions is the sole supplier of voclosporin capsules, and a sole supplier handles blistering and packaging of U.S. commercial cartons. In the U.S., LUPKYNIS competes against BENLYSTA (belimumab, marketed by GSK plc) and GAZYVA (obinutuzumab, marketed by Genentech, Inc.), both injectable therapies, as well as off-label use of mycophenolate mofetil and corticosteroids. In February and March 2025, eight generic companies including Hikma, Teva Pharmaceuticals, Dr. Reddy's Laboratories, and Sandoz filed ANDAs challenging the 2037 dosing patents; Aurinia filed patent infringement complaints against each, triggering a Hatch-Waxman 30-month regulatory stay.
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Three sole-source supply relationships expose Aurinia to manufacturing disruption risk with no short-term mitigation path. Lonza serves as the sole drug substance manufacturer at a dedicated Monoplant contracted through March 31, 2030, at a fixed quarterly facility fee of 3.6 million Swiss Francs for exclusive use rights — a cost that continues regardless of production volume. Catalent Pharma Solutions is the sole encapsulator and an unnamed third supplier handles all blistering and packaging of U.S. commercial cartons. The 10-K notes that the long-term commercial success of LUPKYNIS depends in part on the ability of contract manufacturers to supply cGMP-compliant product without interruption, and that an interruption from any sole-source supplier could adversely affect LUPKYNIS commercial sales.
See also: Healthcare · Biotechnology
From Aurinia Pharmaceuticals Inc's most recent 10-K filing, extracted June 9, 2026.
Recent developments
updated 2026-06-17Recent Developments — Aurinia Pharmaceuticals Inc
Latest news
- NEWS Aurinia earnings on deck: Can new leadership sustain growth? By Investing.com - Investing.com Australia — Investing.com Australia neutral
- NEWS Aurinia Pharmaceuticals Completes Successful Tender Offer for Kezar Life Sciences - citybiz — citybiz positive
- NEWS Aurinia Pharmaceuticals (AUPH) Stock Could Be 4.6% Undervalued After New LUPKYNIS Phase 3 Data - simplywall.st — simplywall.st positive
- NEWS Tudor Investment Corp ET AL Buys Shares of 65,964 Aurinia Pharmaceuticals Inc $AUPH - MarketBeat — MarketBeat positive
- NEWS Aurinia Pharmaceuticals Inc - Common Shares (NQ: AUPH - FinancialContent — FinancialContent neutral
Generated 2026-06-17T11:31:47Z.
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Frequently Asked Questions
Wait for pullback to $15.25. BUY gates pass at $16.21, but cyclical risk: PE expanding 1.9x (earnings normalizing) and analyst target reached - limited upside remaining argue for a more patient entry. Engine's entry $15.25 (Support Atr Sticky) is the shallowest technical level that clears the 2:1 A.R:R minimum. Chart setup: Golden cross, above all MAs, RSI 62, MACD bullish. Fundamentals strong but target reached (-8.8% upside). Wait for pullback. Target $16.37 (+1.0%), stop $14.22 (−14.0%), Setup A.R:R 1.6:1. Score 7.0/10, moderate confidence.
Take-profit target: $16.37 (+7.6% upside). Target $16.37 (+1.0%), stop $14.22 (−14.0%), Setup A.R:R 1.6:1. Stop-loss: $14.22.
Cyclical risk: PE expanding 1.9x (earnings normalizing); Analyst target reached - limited upside remaining; Near 52-week high (3.9% away).
Aurinia Pharmaceuticals Inc trades at a P/E of 7.5 (forward 14.5). TrendMatrix value score: 7.1/10. Verdict: Buy (Wait for Entry).
13 analysts cover AUPH with a consensus score of 3.9/5. Average price target: $17.
What does Aurinia Pharmaceuticals Inc do?Aurinia Pharmaceuticals markets LUPKYNIS (voclosporin), the first FDA-approved oral therapy for adult lupus nephritis,...
Aurinia Pharmaceuticals markets LUPKYNIS (voclosporin), the first FDA-approved oral therapy for adult lupus nephritis, generating $271.3 million in 2025 net product sales. Revenue comes from direct U.S. commercialization through specialty pharmacies and a supply and royalty arrangement with Otsuka Pharmaceutical for Japan, EU, UK, and Switzerland markets. Manufacturing relies entirely on sole-source contractors: Lonza for drug substance and Catalent for encapsulation.