Ascendis Pharma pairs 115% YoY growth with elite profitability (71% margins, 119% return on equity) and a wide moat, but cash conversion is a red flag at 2% FCF/net income and the stock is overbought with only 8.8% upside to the analyst target.
Thesis pillars
- Elite Profitability Wide Moat→Stable
- Triple Digit Revenue Growth→Stable
- Weak Cash Conversion→Stable
- +2 more pillars — see the Why tab for full reasoning
Pillars as of Nov 1, 2026
Ascendis Pharma A/S (ASND) Stock Analysis
Healthcare · Biotechnology
Hold if already holding. Not a fresh buy at $253.45, but acceptable to hold if already in. Reasons: Thin upside margin: 8.3%; Consecutive earnings misses (2).
Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency;... Read more
Hold if already holding. Not a fresh buy at $253.45, but acceptable to hold if already in. Reasons: Thin upside margin: 8.3%; Consecutive earnings misses (2). Chart setup: No clear chart pattern; technical signals are mixed. Wide-moat business. Accumulate on weakness. | News modifier -1 (STRONG_BUY_WAIT → HOLD_IF_HOLDING) Score 6.9/10, high confidence.
Passes 7/8 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, earnings proximity no date, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: speculative.
Recent developments
No fresh coverage since Oct 21, 2026
Recent Developments — Ascendis Pharma A/S
Latest news
- NEWS Morgan Stanley Maintains Ascendis Pharma A/S(ASND.US) With Buy Rating, Maintains Target Price $273 - Moomoo — Moomoo Oct 21, 2026 neutral
- NEWS Ascendis Pharma Grants New Employee Warrants and Updates Articles of Association - TipRanks — TipRanks Oct 14, 2026 neutral
- NEWS Ascendis Pharma (ASND) Stock May Be Undervalued After Rare Disease Data News - Simply Wall Street — Simply Wall Street Oct 14, 2026 positive
- NEWS Ascendis Pharma Falls as Investors Reassess Novo Rights Reversion and Pipeline Execution Risk - Moomoo — Moomoo Sep 23, 2026 negative
- NEWS Ascendis Pharma Falls as Investors Reassess Novo Rights Reversion and Pipeline Execution Risk - moomoo.com — moomoo.com Sep 23, 2026 negative
Latest item Oct 21, 2026 · Generated 2026-11-06T11:28:04Z.
Thesis
Key Metrics
Quality Signals
Options Flow
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Editorial policy
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Rating Breakdown
2 floor-breakers·1 ceiling hit
No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static
Technicals below the gate floor. Component breakdown shows what dragged the score down.static
Price Targets
Position Sizing
Risk Alerts
Earnings
Verdict History
Frequently Asked Questions
Hold if already holding. Not a fresh buy at $253.45, but acceptable to hold if already in. Reasons: Thin upside margin: 8.3%; Consecutive earnings misses (2). Chart setup: No clear chart pattern; technical signals are mixed. Wide-moat business. Accumulate on weakness. | News modifier -1 (STRONG_BUY_WAIT → HOLD_IF_HOLDING) Analyst target $274.42 (+8.3%), stop $241.87 (−4.8%), A.R:R 0.7:1. Score 6.9/10, high confidence.
Analyst target: $274.42 (+8.3% upside). Analyst target $274.42 (+8.3%), stop $241.87 (−4.8%), A.R:R 0.7:1. Stop-loss: $241.87.
Thin upside margin: 8.3%; Consecutive earnings misses (2); Overbought (RSI 81).
Ascendis Pharma A/S trades at a P/E of 19.4 (forward 25.4). TrendMatrix value score: 4.6/10. Verdict: Hold.
28 analysts rate ASND, with a consensus score of 4.4/5. 21 analysts publish price targets averaging $305.
What does Ascendis Pharma A/S do?Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for...
Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency; and YORVIPATH, a once-daily subcutaneous injection for the treatment of adults with chronic hypoparathyroidism. It is also developing a pipeline of three independent endocrinology rare disease product candidates in clinical development, as well as focuses on advancing oncology therapeutic candidates. The company was incorporated in 2006 and is based in Hellerup, Denmark.