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ASNDAscendis Pharma A/SHold7.0·$225.25
HoldHigh Confidence
Investment thesis

A high-growth biotech with 144% year-over-year revenue expansion, elite growth-plus-profitability metrics, and wide competitive advantages, but persistent questions about cash conversion quality and a history of large earnings misses temper the case despite a favorable 2.9-to-1 risk/reward and 20% upside to the analyst target.

Thesis pillars

  • Elite Growth And Moat→Stable
  • Free Cash Flow Conversion Gap→Stable
  • Earnings Track Record Volatile↑Improving
  • +1 more pillar — see the Why tab for full reasoning

Full reasoning →

Open full analysis

Ascendis Pharma A/S (ASND) Stock Analysis

Range Bound setup

HoldGrowthQualityHigh Confidence

Healthcare · Biotechnology

Hold if already holding. Not a fresh buy at $225.25, but acceptable to hold if already in. Reason: Consecutive earnings misses (2).

Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency;... Read more

$225.25+22.9% A.UpsideScore 7.0/10#4 of 241 Biotechnology
QualityF-score8 / 9FCF yield0.09%
Stop $213.39Analyst target $276.79(−10% haircut)A.R:R 4.3:1
Analyst consensus$307.55+36.5%21 analysts
$276.79Analyst target
$225.25price
$307.55mean
$351

Hold if already holding. Not a fresh buy at $225.25, but acceptable to hold if already in. Reason: Consecutive earnings misses (2). Chart setup: RSI 42 mid-range, Bollinger mid-band. Wide-moat business. Accumulate on weakness. | News modifier -1 (STRONG_BUY_WAIT → HOLD_IF_HOLDING) Score 7.0/10, high confidence.

Passes 6/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity no date, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-10-17

Thesis

Rewards
V7 flight-to-quality bonus: +0.5 (Q=8.3 in RISK_OFF)
Sector modifier (Healthcare): +0.5
Strong overall score: 7.0/10
Risks
Consecutive earnings misses (2)

Key Metrics

P/E (TTM)17.4
P/E (Fwd)21.0
Mkt Cap$14.9B
EV/EBITDA55.1
Profit Mgn70.8%
ROE118.8%
Rev Growth114.7%
Beta—
DividendNone
Rating analysts28

Quality Signals

Piotroski F8/9MoatWideCompounder✓

Options Flow

P/C18.05bearish

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

1 floor-breaker·2 ceiling hits

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Surprise Avg
0.0
Earnings History
1.1
Erm
5.0
News Activity
5.0
Earnings concerns: 1B/2M
GatesMomentum 4.0<4.5A.R:R 4.3 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY NO DATESEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Speculative
RSI
42 · Neutral
↓ 20D MA↓ 50D MA↓ 200D MAGOLDEN CROSSSupport $219.52Resistance $241.50

Price Targets

$213
$277
A.Upside+22.9%
A.R:R4.3:1

Position Sizing

ConvictionNone
Suggested %0%
Max %0%
RegimeRisk-Off

Risk Alerts

! News modifier -1: STRONG_BUY_WAIT → HOLD_IF_HOLDING
! momentum at 4.0 (below the engine's 4.5 threshold)

Earnings

B
M
M
M
1/4 beats

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is ASND stock a buy right now?

Hold if already holding. Not a fresh buy at $225.25, but acceptable to hold if already in. Reason: Consecutive earnings misses (2). Chart setup: RSI 42 mid-range, Bollinger mid-band. Wide-moat business. Accumulate on weakness. | News modifier -1 (STRONG_BUY_WAIT → HOLD_IF_HOLDING) Analyst target $276.79 (+22.9%), stop $213.39 (−5.6%), A.R:R 4.3:1. Score 7.0/10, high confidence.

What is the ASND stock price target?

Analyst target: $276.79 (+22.9% upside). Analyst target $276.79 (+22.9%), stop $213.39 (−5.6%), A.R:R 4.3:1. Stop-loss: $213.39.

What are the risks of investing in ASND?

Consecutive earnings misses (2).

Is ASND overvalued or undervalued?

Ascendis Pharma A/S trades at a P/E of 17.4 (forward 21.0). TrendMatrix value score: 5.6/10. Verdict: Hold.

What do analysts say about ASND?

28 analysts cover ASND with a consensus score of 4.4/5. Average price target: $308.

What does Ascendis Pharma A/S do?Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for...

Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency; and YORVIPATH, a once-daily subcutaneous injection for the treatment of adults with chronic hypoparathyroidism. It is also developing a pipeline of three independent endocrinology rare disease product candidates in clinical development, as well as focuses on advancing oncology therapeutic candidates. The company was incorporated in 2006 and is based in Hellerup, Denmark.

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