Skip to main content
HRMYHarmony Biosciences Holdings, IHold6.4·$33.94-0.70%
Open full analysis

Harmony Biosciences Holdings, I (HRMY) Stock Analysis

Momentum Cont setup

HoldModerate Confidence

Healthcare · Biotechnology

Hold if already holding. Not a fresh buy at $33.94, but acceptable to hold if already in. Reasons: Concentration risk — Product: WAKIX; Concentration risk — Supplier: sole-source suppliers and manufacturers.

Harmony Biosciences commercializes WAKIX (pitolisant), the only FDA-approved non-scheduled narcolepsy treatment, cleared for excessive daytime sleepiness and cataplexy in adult and pediatric patients. WAKIX generated $868.5 million in net product revenue in fiscal 2025 from a... Read more

$33.94+14.1% A.UpsideScore 6.4/10#11 of 157 Biotechnology
QualityF-score9 / 9FCF yield7.57%
Stop $31.46Target $38.60(analyst − 13%)A.R:R 1.1:1
Analyst target$44.36+30.7%11 analysts
$38.60our TP
$33.94price
$44.36mean
$28
$85

Hold if already holding. Not a fresh buy at $33.94, but acceptable to hold if already in. Reasons: Concentration risk — Product: WAKIX; Concentration risk — Supplier: sole-source suppliers and manufacturers. Chart setup: Trend continuation, RSI 66, MACD bullish. Growth is cheap relative to earnings, but the technical setup has not yet produced a breakout above resistance (PEG 0.05, quality 7.8/10, growth 8.3/10). | News modifier -1 (STRONG_BUY_WAIT → HOLD_IF_HOLDING) Score 6.4/10, moderate confidence.

Passes 6/10 gates (positive momentum, clean insider activity, news events none recent, earnings proximity 49d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio and death cross (50MA < 200MA). Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-17
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Aug 4, 202649d to earnings· next earnings call

Thesis

Rewards
High-quality business
Attractive valuation
Strong growth profile
Risks
Concentration risk — Product: WAKIX
Concentration risk — Supplier: sole-source suppliers and manufacturers
Consecutive earnings misses (3)

Key Metrics

P/E (TTM)13.8
P/E (Fwd)6.1
Mkt Cap$2.0B
EV/EBITDA7.0
Profit Mgn16.2%
ROE17.9%
Rev Growth16.6%
Beta0.97
DividendNone
Rating analysts17

Quality Signals

Piotroski F9/9MoatWideCompounder

Options Flow

P/C0.76neutral
IV97%elevated
Max Pain$43+25.2% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHProductWAKIX
    10-K Item 1A: 'we expect the sales of WAKIX to generate substantially all of our revenue for the foreseeable future'
  • HIGHSuppliersole-source suppliers and manufacturers
    10-K Item 1A: 'We rely completely on third parties to manufacture and distribute our supply of WAKIX and our product candidates, including certain sole-source suppliers and manufacturers'
  • HIGHSupplierBioprojet license
    10-K Item 1A: 'We rely on our license agreements with Bioprojet to provide rights to the core intellectual property relating to pitolisant'

Material Events(8-K, last 90d)

  • 2026-04-14Item 5.02MEDIUM
    CFO Sandip Kapadia stepped down effective April 14, 2026 to pursue other career opportunities. Glenn Reicin appointed as successor CFO effective the same day.
    SEC filing →
  • 2026-04-02Item 5.02LOW
    Peter Anastasiou appointed Senior EVP and COO effective April 2, 2026. In connection with appointment, resigned as Class III board director effective same date. No disagreement with Company or Board cited.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

Show full disclosure ▾

About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

Not investment advice. TrendMatrix is not a registered investment adviser. Our content is for informational and educational purposes only. Consult your own licensed investment adviser, broker, or tax professional before making any investment decision.

Conflicts and positions. The TrendMatrix editorial team frequently holds personal long-term positions in securities discussed. We disclose positions held at the time of publication on each piece. We maintain a trading-window policy: we do not initiate or close positions in the same direction as a TrendMatrix publication within 24 hours before or 72 hours after publication.

No paid promotion. TrendMatrix does not accept payment from any issuer, broker, or third party in exchange for coverage of any security. Our sole compensation is subscription revenue.

No fiduciary duty. No fiduciary, advisory, or agency relationship is created between you and TrendMatrix by reading our content or subscribing to our service.

Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

1 floor-breaker

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/3M
GatesA.R:R 1.1 < 1.5@spotDeath cross (50MA < 200MA)Momentum 4.9<5.5 (soft — BUY_NOW allowed but watch)Executive change: officer departure/appointmentMomentum 4.9>=4.5Insider activity: OKNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 49d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARMomentum ContSuitability: Aggressive
RSI
66 · Neutral
20D MA 50D MA 200D MADEATH CROSSSupport $29.70Resistance $35.95

Price Targets

$31
$39
A.Upside+13.7%
A.R:R1.1:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! NEWS_MOD=-1: STRONG_BUY_WAIT → HOLD_IF_HOLDING
! asymmetry at 1.1 (below the engine's 1.5 threshold)@spot
! Death cross — 50-day MA below 200-day MA

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-04 (49d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is HRMY stock a buy right now?

Hold if already holding. Not a fresh buy at $33.94, but acceptable to hold if already in. Reasons: Concentration risk — Product: WAKIX; Concentration risk — Supplier: sole-source suppliers and manufacturers. Chart setup: Trend continuation, RSI 66, MACD bullish. Growth is cheap relative to earnings, but the technical setup has not yet produced a breakout above resistance (PEG 0.05, quality 7.8/10, growth 8.3/10). | News modifier -1 (STRONG_BUY_WAIT → HOLD_IF_HOLDING) Target $38.60 (+13.7%), stop $31.46 (−7.9%), A.R:R 1.1:1. Score 6.4/10, moderate confidence.

What is the HRMY stock price target?

Take-profit target: $38.60 (+14.1% upside). Target $38.60 (+13.7%), stop $31.46 (−7.9%), A.R:R 1.1:1. Stop-loss: $31.46.

What are the risks of investing in HRMY?

Concentration risk — Product: WAKIX; Concentration risk — Supplier: sole-source suppliers and manufacturers; Consecutive earnings misses (3).

Is HRMY overvalued or undervalued?

Harmony Biosciences Holdings, I trades at a P/E of 13.8 (forward 6.1). TrendMatrix value score: 8.5/10. Verdict: Hold.

What do analysts say about HRMY?

17 analysts cover HRMY with a consensus score of 3.8/5. Average price target: $44.

What does Harmony Biosciences Holdings, I do?Harmony Biosciences commercializes WAKIX (pitolisant), the only FDA-approved non-scheduled narcolepsy treatment,...

Harmony Biosciences commercializes WAKIX (pitolisant), the only FDA-approved non-scheduled narcolepsy treatment, cleared for excessive daytime sleepiness and cataplexy in adult and pediatric patients. WAKIX generated $868.5 million in net product revenue in fiscal 2025 from a U.S. narcolepsy market valued at approximately $3.1 billion. The company holds an exclusive U.S. license from Bioprojet and relies entirely on third-party contract manufacturers, including certain sole-source suppliers.

Related stocks: AUPH (Aurinia Pharmaceuticals Inc) · HALO (Halozyme Therapeutics, Inc.) · ADMA (ADMA Biologics Inc) · KRYS (Krystal Biotech, Inc.) · AAPG (Ascentage Pharma Group Internat)
Home Stocks HRMY

Latest news

Latest News

Business Wire21d ago
Investing.com UK56d agoAnalyst
Simplywall.st56d ago
GuruFocus63d ago
Seeking Alpha34d agoEarnings
GuruFocus42d agoEarnings
MSN50d agoLegal
GuruFocus57d ago
MarketBeat57d ago
Seeking Alpha57d agoLegal
Seeking Alpha57d agoProduct
GuruFocus64d ago
Investing.com Australia64d agoLeadership Change
Marketscreener.com64d ago
Marketscreener.com64d agoLeadership Change
TipRanks64d agoLeadership Change
Yahoo Finance64d agoProduct
Insider Monkey36d agoEarnings
Stocktwits8d ago
Benzinga71d ago
Loading more...