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RXRXRecursion Pharmaceuticals, Inc.Sell4.2·$3.96+4.21%
SellModerate Confidence
Investment thesis

Recursion Pharmaceuticals is an artificial intelligence-driven drug discovery company with analyst targets implying 102% upside and 3 of the last 4 quarters showing positive earnings surprises, but a confirmed death cross, 33% short interest, and near-zero quality scores reflect deep fundamental concerns about the pre-revenue business model.

Thesis pillars

  • Analyst Upside And Ai Discovery PlatformStable
  • Improving Earnings Surprise TrendStable
  • Death Cross Confirmed DowntrendStable
  • +1 more pillar — see the Why tab for full reasoning

Full reasoning →

Open full analysis

Recursion Pharmaceuticals, Inc. (RXRX) Stock Analysis

Recovery setup

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $3.96: Quality below floor (1.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 3.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 37%; Below-average business quality; Below long-term trend.

Recursion Pharmaceuticals is a clinical-stage TechBio company with an AI-native drug discovery platform (Recursion OS) and five wholly-owned clinical programs, with no products approved for commercial sale. Revenue derives from collaboration agreements with Roche, Genentech,... Read more

$3.96+46.0% A.UpsideScore 4.2/10#228 of 253 Biotechnology
QualityF-score2 / 9FCF yield-8.82%
Stop $3.68Target $5.78(analyst − 13%)A.R:R 3.1:1
Analyst target$6.64+67.7%7 analysts
$5.78our TP
$3.96price
$6.64mean
$3
$10

Sell if holding. Engine safety override at $3.96: Quality below floor (1.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 3.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 37%; Below-average business quality; Below long-term trend. Chart setup: Death cross but MACD improving, RSI 80. Score 4.2/10, moderate confidence.

Passes 7/9 gates (positive momentum, favorable risk/reward ratio, clean insider activity, news events none recent, earnings proximity 31d clear, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

10-K grounded · weekly refresh

About Recursion Pharmaceuticals, Inc.

About Recursion Pharmaceuticals, Inc.

Recursion Pharmaceuticals reported an accumulated deficit of $2.1 billion as of December 31, 2025, reflecting its entirely pre-commercial stage: no products are approved for sale. The clinical pipeline includes five wholly-owned programs, with the Phase 1b/2 MEK1/2 inhibitor REC-4881 in familial adenomatous polyposis (FAP) representing the first clinical validation of the Recursion OS platform. The company has received over $500 million in partner payments from Roche, Genentech, Sanofi, Bayer, and Merck KGaA to date.

Recursion generates revenue through funded research and development collaboration agreements rather than product sales. Operating revenue has primarily come from agreements with Roche and Genentech ($213 million in upfront and milestone payments), Sanofi ($134 million including a $4 million fifth milestone achieved in February 2026), Takeda, and Bayer. The collaboration model provides near-term cash flows while the company advances internal programs across oncology and rare disease and builds pipelines for partners in oncology, neuroscience, and immunology. The Recursion OS synthesizes phenomics data from over 2 million experiments per week, AI-driven generative chemistry design — synthesizing approximately 90% fewer compounds than the industry average — and clinical development intelligence. Through the Roche and Genentech collaboration, six Phenomaps have been accepted, including a $30 million Microglia Map milestone in October 2025.

Show full overview

The binary risk in Recursion's portfolio centers on REC-4881, which delivered the first clinical validation of the Recursion OS with a median 43% polyp burden reduction at week 13 and 53% at week 25 in FAP patients. The company plans to engage with the FDA in the first half of 2026 to define a registration path while further optimizing dosing schedule in the ongoing TUPELO trial. In March 2026, Vicki Goodman, M.D. became Chief Medical Officer, succeeding David Mauro, M.D., Ph.D. — a transition disclosed via Form 8-K on March 25, 2026 — with Dr. Mauro continuing in an advisory capacity through May 2026, a leadership change that could affect clinical execution during this pivotal FDA engagement period.

See also: Healthcare · Biotechnology

From Recursion Pharmaceuticals, Inc.'s most recent 10-K filing, extracted June 16, 2026.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-07

Recent Developments — Recursion Pharmaceuticals, Inc.

Generated 2026-07-07T13:32:10Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Wed, Aug 5, 202631d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Quality below floor (1.5 < 4.0)
Value-trap signals (2/5): High leverage (D/E 3.6), Material insider selling (3 sells, 15.11% of cap)

Key Metrics

P/E (TTM)
P/E (Fwd)-4.3
Mkt Cap$2.0B
EV/EBITDA-2.9
Profit Mgn0.0%
ROE-57.2%
Rev Growth-56.1%
Beta0.99
DividendNone
Rating analysts14

Quality Signals

Piotroski F2/9

Options Flow

P/C0.38bullish
IV110%elevated
Max Pain$1-87.4% vs spot

Concentration Risks(10-K Item 1A)

  • MEDIUMpipelineREC-4881
    10-K Item 1: 'the first clinical validation of the Recursion OS, with positive Phase 1b/2 results from our REC-4881 MEK1/2 inhibitor program in FAP'

Material Events(8-K, last 90d)

  • 2026-04-30Item 5.02LOW
    Christopher Gibson, Ph.D., Chair of the Board, informed the company on April 28, 2026 that he will not stand for re-election as a Class II Director at the 2026 Annual Meeting. No disagreement cited. No successor named; Dr. Gibson will continue as Chair until his term expires.
    SEC filing →
  • 2026-03-25Item 5.02MEDIUM
    CMO transition effective April 6, 2026: Vicki Goodman, M.D. appointed as Chief Medical Officer; David Mauro, M.D., Ph.D. departing. Successor named. Dr. Mauro to continue in advisory capacity until May 29, 2026. No disagreement cited.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

4 floor-breakers

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.0
52w Position
1.0
Support Resistance
1.1

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
2.2
Moat
2.5
Current Ratio
7.5
Cash-burning: FCF -268% of revenueNo competitive moatWeak Piotroski F-Score: 2/9Quality concerns

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Growth Rank
1.7
Value Rank
1.9
Quality Rank
2.1

Volatile — 6.3% daily ATR makes tight stops impractical. Position-size conservatively.static

Short Interest
0.0
Volatility
0.0
Implied Vol
0.0
Debt Equity
0.0
Days To Cover
1.5
Max Pain Risk
3.0
Beta
7.0
Put Call
10.0
High short interest justified: 37%High IV: 110%Above max pain $0
GatesDeath cross (50MA < 200MA)Executive change: officer departure/appointmentMomentum 6.8>=5.5A.R:R 3.1 ≥ 1.5Insider activity: OKNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 31d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRecoverySuitability: Speculative
RSI
80 · Overbought
20D MA 50D MA 200D MADEATH CROSSSupport $2.95Resistance $4.09

Price Targets

$4
$6
A.Upside+46.0%
A.R:R3.1:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.5 < 4.0)
! Value-trap signals (2/5): High leverage (D/E 3.6), Material insider selling (3 sells, 15.11% of cap)

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-08-05 (31d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is RXRX stock a buy right now?

Sell if holding. Engine safety override at $3.96: Quality below floor (1.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 3.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 37%; Below-average business quality; Below long-term trend. Chart setup: Death cross but MACD improving, RSI 80. Prior stop was $3.68. Score 4.2/10, moderate confidence.

What is the RXRX stock price target?

Take-profit target: $5.78 (+46.0% upside). Prior stop was $3.68. Stop-loss: $3.68.

What are the risks of investing in RXRX?

Quality below floor (1.5 < 4.0); Value-trap signals (2/5): High leverage (D/E 3.6), Material insider selling (3 sells, 15.11% of cap).

Is RXRX overvalued or undervalued?

Recursion Pharmaceuticals, Inc. trades at a P/E of N/A (forward -4.3). TrendMatrix value score: 5.4/10. Verdict: Sell.

What do analysts say about RXRX?

14 analysts cover RXRX with a consensus score of 3.7/5. Average price target: $7.

What does Recursion Pharmaceuticals, Inc. do?Recursion Pharmaceuticals is a clinical-stage TechBio company with an AI-native drug discovery platform (Recursion OS)...

Recursion Pharmaceuticals is a clinical-stage TechBio company with an AI-native drug discovery platform (Recursion OS) and five wholly-owned clinical programs, with no products approved for commercial sale. Revenue derives from collaboration agreements with Roche, Genentech, Sanofi, Bayer, and Merck KGaA, having received over $500 million in partner payments to date against an accumulated deficit of $2.1 billion as of December 31, 2025.

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