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PRLDPrelude Therapeutics IncorporatHold5.1·$4.97-0.40%
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Prelude Therapeutics Incorporat (PRLD) Stock Analysis

Breakout setup

HoldVALUE-TRAP 3/5QualityModerate Confidence

Healthcare · Biotechnology

Hold if already holding. Not a fresh buy at $4.97, but acceptable to hold if already in. Reasons: Market cap $396M below $400M minimum; Value-trap signals (3/5): Margin compression (op margin -240.5%), Material insider selling (4 sells, 0.03% of cap), Negative free cash flow.

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative... Read more

$4.97+36.8% A.UpsideScore 5.1/10#162 of 255 Biotechnology
QualityF-score5 / 9FCF yield-4.53%
Stop $4.62Target $6.80(analyst − 15%)A.R:R 2.5:1
Analyst target$8.00+61.0%3 analysts
$6.80our TP
$4.97price
$8.00mean
$10

Hold if already holding. Not a fresh buy at $4.97, but acceptable to hold if already in. Reasons: Market cap $396M below $400M minimum; Value-trap signals (3/5): Margin compression (op margin -240.5%), Material insider selling (4 sells, 0.03% of cap), Negative free cash flow. Chart setup: Golden cross, above all MAs, RSI 60, MACD bullish. Market cap $396M below $400M minimum. Not in investable universe. Score 5.1/10, moderate confidence.

Passes 8/9 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 36d clear, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 13, 202636d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Market cap $396M below $400M minimum
Value-trap signals (3/5): Margin compression (op margin -240.5%), Material insider selling (4 sells, 0.03% of cap), Negative free cash flow

Key Metrics

P/E (TTM)
P/E (Fwd)-5.3
Mkt Cap$396M
EV/EBITDA-5.3
Profit Mgn0.0%
ROE-95.2%
Rev Growth
Beta0.95
DividendNone
Rating analysts9

Quality Signals

Piotroski F5/9MoatNarrow

Options Flow

P/C6.00bearish
IV213%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.1
Value Rank
2.5
Growth Rank
5.0

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
5.6
Moat
6.2
Current Ratio
7.1
Gross Margin
10.0
Cash-burning: FCF -107% of revenue
GatesMomentum 4.7<5.5 (soft — BUY_NOW allowed but watch)Momentum 4.7>=4.5A.R:R 2.5 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 36d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARBreakoutSuitability: Speculative
RSI
60 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $3.76Resistance $5.69

Price Targets

$5
$7
A.Upside+36.8%
A.R:R2.5:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Market cap $396M below $400M minimum
! Value-trap signals (3/5): Margin compression (op margin -240.5%), Material insider selling (4 sells, 0.03% of cap), Negative free cash flow

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-08-13 (36d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is PRLD stock a buy right now?

Hold if already holding. Not a fresh buy at $4.97, but acceptable to hold if already in. Reasons: Market cap $396M below $400M minimum; Value-trap signals (3/5): Margin compression (op margin -240.5%), Material insider selling (4 sells, 0.03% of cap), Negative free cash flow. Chart setup: Golden cross, above all MAs, RSI 60, MACD bullish. Market cap $396M below $400M minimum. Not in investable universe. Target $6.80 (+36.8%), stop $4.62 (−7.6%), A.R:R 2.5:1. Score 5.1/10, moderate confidence.

What is the PRLD stock price target?

Take-profit target: $6.80 (+36.8% upside). Target $6.80 (+36.8%), stop $4.62 (−7.6%), A.R:R 2.5:1. Stop-loss: $4.62.

What are the risks of investing in PRLD?

Market cap $396M below $400M minimum; Value-trap signals (3/5): Margin compression (op margin -240.5%), Material insider selling (4 sells, 0.03% of cap), Negative free cash flow.

Is PRLD overvalued or undervalued?

Prelude Therapeutics Incorporat trades at a P/E of N/A (forward -5.3). TrendMatrix value score: 5.4/10. Verdict: Hold.

What do analysts say about PRLD?

9 analysts cover PRLD with a consensus score of 4.2/5. Average price target: $8.

What does Prelude Therapeutics Incorporat do?Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and...

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET. The company has collaboration with AbCellera Biologics to discover, develop, and commercialize novel degrader antibody conjugates. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.

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