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XERSXeris Biopharma Holdings, Inc.Sell6.3·$8.34+4.28%
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Xeris Biopharma Holdings, Inc. (XERS) Stock Analysis

Recovery setup

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Drug Manufacturers - Specialty & Generic

Sell if holding. At $8.34, A.R:R 1.2:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Leverage penalty (D/E 19.9): -1.5; Overbought (RSI 89).

Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe... Read more

QualityF-score8 / 9FCF yield2.95%
Stop $7.74Target $9.82(analyst − 13%)A.R:R 1.2:1
Analyst target$11.29+35.3%7 analysts
$9.82our TP
$8.34price
$11.29mean
$18

Sell if holding. At $8.34, A.R:R 1.2:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Leverage penalty (D/E 19.9): -1.5; Overbought (RSI 89). Chart setup: Death cross but MACD improving, RSI 89. Score 6.3/10, moderate confidence.

Passes 7/9 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, earnings proximity 33d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: aggressive.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 6, 202633d to earnings· next earnings call

Thesis

Rewards
Strong growth profile
Positive momentum
Risks
Leverage penalty (D/E 19.9): -1.5
Overbought (RSI 89)
Value-trap signals (2/5): High leverage (D/E 19.9), Material insider selling (6 sells, 0.04% of cap)

Key Metrics

P/E (TTM)118.3
P/E (Fwd)21.0
Mkt Cap$1.4B
EV/EBITDA32.8
Profit Mgn3.8%
ROE
Rev Growth38.3%
Beta0.85
DividendNone
Rating analysts13

Quality Signals

Piotroski F8/9MoatNarrow

Options Flow

P/C0.33bullish
IV105%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers·1 ceiling hit

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.1
Support Resistance
0.4
52w Position
6.4

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Value Rank
1.7
Quality Rank
4.9
Growth Rank
7.9
GatesA.R:R 1.2 < 1.5@spotDeath cross (50MA < 200MA)Momentum 7.5>=5.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 33d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRecoverySuitability: Aggressive
RSI
89 · Overbought
20D MA 50D MA 200D MADEATH CROSSSupport $5.93Resistance $8.38

Price Targets

$8
$10
A.Upside+17.7%
A.R:R1.2:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! asymmetry at 1.2 (below the engine's 1.5 threshold)@spot

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-06 (33d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is XERS stock a buy right now?

Sell if holding. At $8.34, A.R:R 1.2:1 is below the 1.5:1 minimum. Reward from here is too thin for a buy — the engine flags exit. Additional concerns: Leverage penalty (D/E 19.9): -1.5; Overbought (RSI 89). Chart setup: Death cross but MACD improving, RSI 89. Prior stop was $7.74. Score 6.3/10, moderate confidence.

What is the XERS stock price target?

Take-profit target: $9.82 (+18.6% upside). Prior stop was $7.74. Stop-loss: $7.74.

What are the risks of investing in XERS?

Leverage penalty (D/E 19.9): -1.5; Overbought (RSI 89); Value-trap signals (2/5): High leverage (D/E 19.9), Material insider selling (6 sells, 0.04% of cap).

Is XERS overvalued or undervalued?

Xeris Biopharma Holdings, Inc. trades at a P/E of 118.3 (forward 21.0). TrendMatrix value score: 5.7/10. Verdict: Sell.

What do analysts say about XERS?

13 analysts cover XERS with a consensus score of 4.2/5. Average price target: $11.

What does Xeris Biopharma Holdings, Inc. do?Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing...

Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase 3 clinical trial for the treatment of hypothyroidism. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.

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