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Scholar Rock Holding Corporatio (SRRK) Stock Analysis

SellModerate Confidence

Healthcare · Biotechnology

Earnings in 7 days (2026-05-07). Expect elevated volatility around the report — consider waiting for post-earnings price action before new entries.

Sell if holding. Engine safety override at $46.02: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.3/10 and A.R:R 1.7:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Elevated put/call ratio: 32.19; Below-average business quality.

Scholar Rock is a pre-commercial biopharmaceutical company developing anti-myostatin antibodies for rare neuromuscular diseases, led by apitegromab for spinal muscular atrophy (SMA). The company submitted a BLA to the FDA in January 2025 but received a Complete Response Letter... Read more

$46.02+13.0% A.UpsideScore 4.3/10#139 of 158 Biotechnology
Stop $43.89Target $51.96(analyst − 10%)A.R:R 1.7:1
Analyst target$57.73+25.5%15 analysts
$51.96our TP
$46.02price
$57.73mean
$70

Sell if holding. Engine safety override at $46.02: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.3/10 and A.R:R 1.7:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Elevated put/call ratio: 32.19; Below-average business quality. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Score 4.3/10, moderate confidence.

Passes 5/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear). Fails on weak momentum and earnings proximity 7d<=7d. Suitability: moderate.

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Product: apitegromab
Quality below floor (1.7 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-21.6
Mkt Cap$5.5B
EV/EBITDA-13.2
Profit Mgn0.0%
ROE-123.1%
Rev Growth
Beta0.69
DividendNone
Rating analysts22

Quality Signals

Piotroski F4/9

Options Flow

P/C32.19bearish
IV74%elevated
Max Pain$30-34.8% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHProductapitegromab
    10-K Item 1A: 'We have never commercialized a product and are in the process of building and scaling our business for potential commercialization of apitegromab in the United States and Europe'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
4.4
Moat
5.0
Current Ratio
6.0
Cash-burning (FCF negative)No competitive moatQuality concerns

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.0
Value Rank
5.0
Growth Rank
5.0

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Volume
0.0
Obv
1.0
Ma Position
4.0
Rsi
8.5
Oversold in uptrend (RSI 22)Volume distribution (falling OBV)Above 200-day MA

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Surprise Avg
0.0
Earnings History
1.1
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/2MEarnings in 7 days
GatesMomentum 2.7<4.5EARNINGS PROXIMITY 7d<=7dA.R:R 1.7 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARSuitability: Moderate
RSI
22 · Oversold
20D MA 50D MA 200D MAGOLDEN CROSSSupport $45.25Resistance $51.62

Price Targets

$44
$52
A.Upside+12.9%
A.R:R1.7:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.7 < 4.0)
! Momentum score 2.7/10 — below 4.5 minimum
! EARNINGS_PROXIMITY:7d<=7d

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-05-07 (7d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is SRRK stock a buy right now?

Sell if holding. Engine safety override at $46.02: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.3/10 and A.R:R 1.7:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Elevated put/call ratio: 32.19; Below-average business quality. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Prior stop was $43.89. Score 4.3/10, moderate confidence.

What is the SRRK stock price target?

Take-profit target: $51.96 (+13.0% upside). Prior stop was $43.89. Stop-loss: $43.89.

What are the risks of investing in SRRK?

Concentration risk — Product: apitegromab; Quality below floor (1.7 < 4.0).

Is SRRK overvalued or undervalued?

Scholar Rock Holding Corporatio trades at a P/E of N/A (forward -21.6). TrendMatrix value score: 6.0/10. Verdict: Sell.

What do analysts say about SRRK?

22 analysts cover SRRK with a consensus score of 4.4/5. Average price target: $58.

What does Scholar Rock Holding Corporatio do?Scholar Rock is a pre-commercial biopharmaceutical company developing anti-myostatin antibodies for rare neuromuscular...

Scholar Rock is a pre-commercial biopharmaceutical company developing anti-myostatin antibodies for rare neuromuscular diseases, led by apitegromab for spinal muscular atrophy (SMA). The company submitted a BLA to the FDA in January 2025 but received a Complete Response Letter in September 2025 due to a third-party fill-finish facility GMP deficiency, delaying potential US commercialization.

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