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NGNENeurogene Inc.Sell5.2·$35.20+3.90%
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Neurogene Inc. (NGNE) Stock Analysis

Inst Constrain edge

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $35.20: Quality below floor (1.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 6.6:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 28%; Below-average business quality.

Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The company's product candidates include NGN-401 that is packaged in an adeno-associated virus 9, which is in Phase 1/2 clinical trial for the treatment of Rett... Read more

$35.20+99.4% A.UpsideScore 5.2/10#118 of 258 Biotechnology
QualityF-score2 / 9FCF yield-6.79%
Stop $32.87Target $70.47(analyst − 13%)A.R:R 6.6:1
Analyst target$81.00+130.1%7 analysts
$70.47our TP
$35.20price
$81.00mean
$180

Sell if holding. Engine safety override at $35.20: Quality below floor (1.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 6.6:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 28%; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Score 5.2/10, moderate confidence.

Passes 7/7 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity 38d clear, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-05

Recent Developments — Neurogene Inc.

Generated 2026-07-05T07:10:31Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Aug 11, 202638d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Quality below floor (1.2 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-6.5
Mkt Cap$704M
EV/EBITDA-3.0
Profit Mgn0.0%
ROE-37.3%
Rev Growth
Beta1.96
DividendNone
Rating analysts15

Quality Signals

Piotroski F2/9

Options Flow

P/C0.63bullish
IV118%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

3 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
2.2
Moat
3.2
Current Ratio
5.0
Cash-burning (FCF negative)No competitive moatWeak Piotroski F-Score: 2/9Quality concerns

Volatile — 5.9% daily ATR makes tight stops impractical. Position-size conservatively.static

Days To Cover
0.0
Volatility
0.0
Implied Vol
0.0
Short Interest
0.7
Debt Equity
1.2
Beta
3.5
News Risk
5.5
Put Call
9.1
High short interest justified: 28%High IV: 118%

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.0
Support Resistance
0.3
52w Position
9.0
GatesMomentum 7.9>=5.5A.R:R 6.6 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY 38d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Speculative
RSI
74 · Overbought
20D MA 50D MA 200D MAGOLDEN CROSSSupport $24.91Resistance $35.71

Price Targets

$33
$70
A.Upside+100.2%
A.R:R6.6:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.2 < 4.0)

Earnings

B
B
M
M
2/4 beats
Next Earnings2026-08-11 (38d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is NGNE stock a buy right now?

Sell if holding. Engine safety override at $35.20: Quality below floor (1.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 6.6:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 28%; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $32.87. Score 5.2/10, moderate confidence.

What is the NGNE stock price target?

Take-profit target: $70.47 (+99.4% upside). Prior stop was $32.87. Stop-loss: $32.87.

What are the risks of investing in NGNE?

Quality below floor (1.2 < 4.0).

Is NGNE overvalued or undervalued?

Neurogene Inc. trades at a P/E of N/A (forward -6.5). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about NGNE?

15 analysts cover NGNE with a consensus score of 4.3/5. Average price target: $81.

What does Neurogene Inc. do?Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The...

Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The company's product candidates include NGN-401 that is packaged in an adeno-associated virus 9, which is in Phase 1/2 clinical trial for the treatment of Rett syndrome; and NGN-101, a conventional gene therapy candidate that is in Phase 1/2 clinical trial to treat CLN5 Batten disease. It has a license agreement with The University of Edinburgh, Virovek, Inc., Sigma-Aldrich Co. LLC., and Leland Stanford Junior University. The company was founded in 2018 and is headquartered in New York, New York.

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