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MRNAModerna, Inc.Sell4.4·$81.80+2.56%
SellModerate Confidence
Investment thesis

Below-floor business quality, negative free cash flow, and a share price that has already exceeded its near-term resistance target combine to create an unattractive risk profile, even as a four-quarter earnings beat streak and strong price momentum indicate the story retains near-term speculative interest.

Thesis pillars

  • Quality Deficiency Cash BurnStable
  • Price Exceeded Resistance TargetStable
  • Elevated Short Interest Bearish PositioningStable
  • +1 more pillar — see the Why tab for full reasoning

Full reasoning →

Open full analysis

Moderna, Inc. (MRNA) Stock Analysis

Catalyst-Driven edge

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $81.80: Quality below floor (3.1 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.4/10. Specifically: High short interest: 18%; Below-average business quality; Rich valuation.

Moderna develops mRNA-based vaccines and therapeutics, currently commercializing three respiratory products — Spikevax, mNEXSPIKE (COVID-19), and mRESVIA (RSV) — that generated $1.9 billion in total revenue in 2025. Revenue is earned from product sales to government and... Read more

$81.80+2.6% A.UpsideScore 4.4/10#202 of 253 Biotechnology
QualityF-score4 / 9FCF yield-0.06%
Stop $76.07Target $83.89(resistance)A.R:R -3.3:1
Analyst target$45.85-43.9%20 analysts
$83.89our TP
$81.80price
$45.85mean
$22

Sell if holding. Engine safety override at $81.80: Quality below floor (3.1 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.4/10. Specifically: High short interest: 18%; Below-average business quality; Rich valuation. Chart setup: No clear chart pattern; technical signals are mixed. Score 4.4/10, moderate confidence.

Passes 7/8 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, earnings proximity 25d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: speculative.

10-K grounded · weekly refresh

About Moderna, Inc.

About Moderna, Inc.

Moderna's three commercialized respiratory vaccines — Spikevax and mNEXSPIKE (COVID-19) and mRESVIA (RSV) — generated $1.9 billion in total revenue in 2025, with mNEXSPIKE launched commercially in the third quarter of 2025 and becoming Moderna's leading product in the U.S. retail channel by year-end. Regulatory filings for a seasonal flu+COVID combination vaccine (mRNA-1083) are under review in Europe and Canada, and for a standalone flu vaccine (mRNA-1010) in the United States, Europe, Canada, and Australia, with the FDA assigning mRNA-1010 a PDUFA goal date of August 5, 2026. The company carries a 35-program pipeline, 6 of which are in late-stage development.

Moderna earns revenue primarily from product sales of COVID and RSV vaccines, competing against Pfizer and Sanofi for COVID market share and against Pfizer and GSK in RSV. The company has been excluded from selling COVID vaccines in many European markets due to a competitor's contract with the European Commission that does not lapse until year-end 2026, limiting near-term geographic expansion. Beyond vaccines, the oncology pipeline is anchored by intismeran autogene (mRNA-4157), a personalized neoantigen therapy advancing in collaboration with Merck across eight Phase 2 and Phase 3 trials; in January 2026, five-year Phase 2b data demonstrated sustained improvement in recurrence-free survival in high-risk melanoma patients. The company plans to fund oncology and rare disease investments from cash generated by the infectious disease franchise as it expands toward a planned six approved products.

Show full overview

The most consequential near-term regulatory binary is the FDA review of mRNA-1010 (standalone flu vaccine), PDUFA August 5, 2026. Following a prior Refusal-to-File letter, Moderna submitted an amended BLA seeking full approval for adults 50-64 and accelerated approval for adults 65 and older. Non-approval or a restricted label could delay the company's plan to expand its commercial franchise and may weigh on its ability to reach cash breakeven — a stated near-term strategic goal — by limiting the revenue base available to fund the oncology and rare disease pipeline.

See also: Healthcare · Biotechnology

From Moderna, Inc.'s most recent 10-K filing, extracted June 11, 2026.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-07

Recent Developments — Moderna, Inc.

Generated 2026-07-07T11:31:44Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Fri, Jul 31, 202625d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Target reached (-49.6% upside)
Quality below floor (3.1 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-19.3
Mkt Cap$31.6B
EV/EBITDA-12.1
Profit Mgn-143.6%
ROE-36.6%
Rev Growth260.2%
Beta0.94
DividendNone
Rating analysts30

Quality Signals

Piotroski F4/9MoatNarrow

Options Flow

P/C0.45bullish
IV109%elevated

Concentration Risks(10-K Item 1A)

  • MEDIUMProductCOVID vaccines
    10-K Item 1: 'In 2025, we achieved total revenue of $1.9 billion, largely from sales of our COVID vaccines'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

Show full disclosure ▾

About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

Not investment advice. TrendMatrix is not a registered investment adviser. Our content is for informational and educational purposes only. Consult your own licensed investment adviser, broker, or tax professional before making any investment decision.

Conflicts and positions. The TrendMatrix editorial team frequently holds personal long-term positions in securities discussed. We disclose positions held at the time of publication on each piece. We maintain a trading-window policy: we do not initiate or close positions in the same direction as a TrendMatrix publication within 24 hours before or 72 hours after publication.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers

Priced at a premium — multiples above sector norms. Needs delivery on growth + margins to justify.static

Ps
0.5
Analyst Target
3.0
Expensive valuation
Low model confidence on this dimension (33%).

Clinical-stage biotech: losses expected pre-commercialisation. Quality floor doesn't distinguish R&D investment from operational decay — components above tell the real story.static

Roe
0.0
Roa
0.0
Fcf Quality
0.0
Piotroski F
4.4
Moat
5.8
Current Ratio
8.2
Cash-burning: FCF -1% of revenue
GatesA.R:R -3.3=NEGATIVEMomentum 8.2>=5.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 25d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Speculative
RSI
87 · Overbought
20D MA 50D MA 200D MAGOLDEN CROSSSupport $45.40Resistance $85.60

Price Targets

$76
$84
A.Upside+2.6%
A.R:R-3.3:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Target reached (-49.6% upside)
! Quality below floor (3.1 < 4.0)
! Negative risk/reward — downside exceeds upside

Earnings

B
B
B
B
4/4 beats
Next Earnings2026-07-31 (25d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is MRNA stock a buy right now?

Sell if holding. Engine safety override at $81.80: Quality below floor (3.1 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.4/10. Specifically: High short interest: 18%; Below-average business quality; Rich valuation. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $76.07. Score 4.4/10, moderate confidence.

What is the MRNA stock price target?

Take-profit target: $83.89 (+2.6% upside). Prior stop was $76.07. Stop-loss: $76.07.

What are the risks of investing in MRNA?

Target reached (-49.6% upside); Quality below floor (3.1 < 4.0).

Is MRNA overvalued or undervalued?

Moderna, Inc. trades at a P/E of N/A (forward -19.3). TrendMatrix value score: 2.0/10. Verdict: Sell.

What do analysts say about MRNA?

30 analysts cover MRNA with a consensus score of 2.8/5. Average price target: $46.

What does Moderna, Inc. do?Moderna develops mRNA-based vaccines and therapeutics, currently commercializing three respiratory products — Spikevax,...

Moderna develops mRNA-based vaccines and therapeutics, currently commercializing three respiratory products — Spikevax, mNEXSPIKE (COVID-19), and mRESVIA (RSV) — that generated $1.9 billion in total revenue in 2025. Revenue is earned from product sales to government and commercial channels, with COVID vaccines accounting for the majority of current income and a 35-program pipeline targeting oncology, rare disease, and infectious disease.

Related stocks: INCY (Incyte Corporation) · ARGX (argenx SE) · ONC (BeOne Medicines Ltd.) · ALNY (Alnylam Pharmaceuticals, Inc.) · HALO (Halozyme Therapeutics, Inc.)
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