Skip to main content

BillionToOne, Inc. (BLLN) Stock Analysis

Range Bound setup

Buy WaitModerate Confidence

Healthcare · Diagnostics & Research

Wait — supporting gate not met yet. Price is at or below entry $80.25 but weak momentum still blocks BUY_NOW. Key risks: Concentration risk — Product: molecular diagnostic tests; Concentration risk — Counterparty: third-party payors (90.0%).

BillionToOne provides single-molecule next-generation sequencing (smNGS) diagnostic tests for prenatal genetic screening (UNITY suite) and oncology liquid biopsy (Northstar Select, Northstar Response). Revenue comes primarily from third-party payor reimbursement for its... Read more

$79.87+27.2% A.UpsideScore 5.6/10#8 of 26 Diagnostics & Research
QualityF-score9 / 9FCF yield0.44%
Entry $80.25(Ma50 Sticky)Stop $63.00Target $102.41(analyst − 13%)A.R:R 1.7:1Setup A.R:R 3.9:1
Analyst target$117.71+47.4%7 analysts
$102.41our TP
$79.87price
$117.71mean
$145

Wait — supporting gate not met yet. Price is at or below entry $80.25 but weak momentum still blocks BUY_NOW. Key risks: Concentration risk — Product: molecular diagnostic tests; Concentration risk — Counterparty: third-party payors (90.0%). Chart setup: RSI 54 mid-range, Bollinger mid-band. Maintain position. Not compelling to add more. | News modifier +1 (HOLD_IF_HOLDING → STRONG_BUY_WAIT) Score 5.6/10, moderate confidence.

Passes 7/8 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news boost analyst 0.70, earnings proximity 77d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: aggressive.

Recent Developments — BillionToOne, Inc.

Generated 2026-05-20T20:21:21Z.

Thesis

Rewards
Sector modifier (Healthcare): +0.5
Positive news sentiment (+0.56)
Strong growth profile
Risks
Concentration risk — Product: molecular diagnostic tests
Concentration risk — Counterparty: third-party payors (90.0%)
Negative momentum

Key Metrics

P/E (TTM)152.4
P/E (Fwd)79.9
Mkt Cap$3.8B
EV/EBITDA78.8
Profit Mgn7.0%
ROE8.7%
Rev Growth83.8%
Beta
DividendNone
Rating analysts14

Quality Signals

Piotroski F9/9MoatWide

Options Flow

P/C5.00bearish
IV81%elevated
Max Pain$40-49.9% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHProductmolecular diagnostic tests
    10-K Item 1A: 'We primarily generate revenue from sales of our molecular diagnostic tests and we are highly dependent on them for our success'
  • HIGHcounterpartythird-party payors90%
    10-K Item 1A: 'Reimbursement from third-party payors for our tests represented more than 90% of our revenue for each of the years ended December 31, 2025 and 2024'

Material Events(8-K, last 90d)

  • 2026-03-04Item 5.02LOW
    Board approved the BillionToOne Annual Incentive Plan effective January 1, 2026, to attract, retain, and motivate top performing employees. Compensatory arrangement only; no officer departures or appointments reported.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

2 floor-breakers·1 ceiling hit

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Volume
0.0
Obv
1.0
Rsi
4.5
Ma Position
4.5
Volume distribution (falling OBV)

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Value Rank
0.6
Quality Rank
4.5
Growth Rank
9.2
Industry growth leader
GatesMomentum 2.0<4.5A.R:R 1.7 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS BOOST ANALYST 0.70EARNINGS PROXIMITY 77d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Aggressive
RSI
54 · Neutral
20D MA 50D MA 200D MASupport $70.81Resistance $107.00

Price Targets

$63
$80
$102
A.Upside+28.2%
A.R:R1.7:1

Position Sizing

ConvictionMedium conviction
Suggested %0.5%
Max %1%
RegimeRisk-Off

Risk Alerts

! NEWS_MOD=+1: HOLD_IF_HOLDING → STRONG_BUY_WAIT
! Momentum score 2.0/10 — below 4.5 minimum

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-05 (77d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is BLLN stock a buy right now?

Wait — supporting gate not met yet. Price is at or below entry $80.25 but weak momentum still blocks BUY_NOW. Key risks: Concentration risk — Product: molecular diagnostic tests; Concentration risk — Counterparty: third-party payors (90.0%). Chart setup: RSI 54 mid-range, Bollinger mid-band. Maintain position. Not compelling to add more. | News modifier +1 (HOLD_IF_HOLDING → STRONG_BUY_WAIT) Target $102.41 (+28.2%), stop $63.00 (−26.8%), Setup A.R:R 3.9:1. Score 5.6/10, moderate confidence.

What is the BLLN stock price target?

Take-profit target: $102.41 (+27.2% upside). Target $102.41 (+28.2%), stop $63.00 (−26.8%), Setup A.R:R 3.9:1. Stop-loss: $63.00.

What are the risks of investing in BLLN?

Concentration risk — Product: molecular diagnostic tests; Concentration risk — Counterparty: third-party payors (90.0%); Negative momentum.

Is BLLN overvalued or undervalued?

BillionToOne, Inc. trades at a P/E of 152.4 (forward 79.9). TrendMatrix value score: 4.1/10. Verdict: Buy (Wait for Entry).

What do analysts say about BLLN?

14 analysts cover BLLN with a consensus score of 4.2/5. Average price target: $118.

What does BillionToOne, Inc. do?BillionToOne provides single-molecule next-generation sequencing (smNGS) diagnostic tests for prenatal genetic...

BillionToOne provides single-molecule next-generation sequencing (smNGS) diagnostic tests for prenatal genetic screening (UNITY suite) and oncology liquid biopsy (Northstar Select, Northstar Response). Revenue comes primarily from third-party payor reimbursement for its molecular diagnostic tests, with >90% from third-party payors in both 2024 and 2025. The patented QCT platform enables single-DNA-molecule sensitivity, differentiating it from conventional NGS.

Related stocks: NEO (NeoGenomics, Inc.) · VCYT (Veracyte, Inc.) · SHC (Sotera Health Company) · WGS (GeneDx Holdings Corp.) · WAT (Waters Corporation)