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ACADIA Pharmaceuticals Inc. (ACAD) Stock Analysis

Recovery setup

SellVALUE-TRAP 3/5Moderate Confidence

Healthcare · Biotechnology

Earnings in 6 days (2026-05-06). Expect elevated volatility around the report — consider waiting for post-earnings price action before new entries.

Sell if holding. Multiple concerning factors at $22.32: Concentration risk — Product: NUPLAZID and DAYBUE; Cyclical risk: PE expanding 2.4x (earnings normalizing).

ACADIA Pharmaceuticals is a biopharmaceutical company commercializing two products: NUPLAZID (pimavanserin) for Parkinson's disease psychosis and DAYBUE (trofinetide) for Rett syndrome, with combined net product sales of $1,071.5 million in 2025. Both are the first and only... Read more

$22.32+28.0% A.UpsideScore 6.2/10#12 of 158 Biotechnology
Stop $21.03Target $28.53(analyst − 10%)A.R:R 4.7:1
Analyst target$31.70+42.0%20 analysts
$28.53our TP
$22.32price
$31.70mean
$17
$45

Sell if holding. Multiple concerning factors at $22.32: Concentration risk — Product: NUPLAZID and DAYBUE; Cyclical risk: PE expanding 2.4x (earnings normalizing). Chart setup: Death cross but MACD improving, RSI 56. Score 6.2/10, moderate confidence.

Passes 5/8 gates (positive momentum, favorable risk/reward ratio, clean insider activity, news events none recent, semi cycle peak clear). Fails on earnings proximity 6d<=7d. Suitability: aggressive.

Thesis

Rewards
Attractive valuation
Strong growth profile
Margin of safety: 36%
Risks
Concentration risk — Product: NUPLAZID and DAYBUE
Cyclical risk: PE expanding 2.4x (earnings normalizing)
Leverage penalty (D/E 4.3): -1.5

Key Metrics

P/E (TTM)9.7
P/E (Fwd)23.3
Mkt Cap$3.8B
EV/EBITDA25.9
Profit Mgn36.5%
ROE39.9%
Rev Growth9.4%
Beta0.83
DividendNone
Rating analysts27

Quality Signals

Piotroski F7/9

Options Flow

P/C0.53bullish
IV71%elevated
Max Pain$13-41.8% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHProductNUPLAZID and DAYBUE
    10-K Item 1A: 'Our prospects are highly dependent on the successful commercialization of our products ... NUPLAZID and DAYBUE'

Material Events(8-K, last 90d)

  • 2026-03-05Item 5.02LOW
    Jonathan M. Poole appointed to Board as Class II director and Audit Committee member effective March 3, 2026. Routine board appointment to fill vacancy.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

10 dimensions · all in-band

GatesEARNINGS PROXIMITY 6d<=7dDeath cross (50MA < 200MA)Executive change: officer departure/appointmentMomentum 5.8>=5.5A.R:R 4.7 ≥ 1.5Insider activity: OKNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARRecoverySuitability: Aggressive
RSI
56 · Neutral
20D MA 50D MA 200D MADEATH CROSSSupport $20.96Resistance $22.86

Price Targets

$21
$29
A.Upside+27.8%
A.R:R4.7:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! EARNINGS_PROXIMITY:6d<=7d

Earnings

B
B
M
M
2/4 beats
Next Earnings2026-05-06 (6d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is ACAD stock a buy right now?

Sell if holding. Multiple concerning factors at $22.32: Concentration risk — Product: NUPLAZID and DAYBUE; Cyclical risk: PE expanding 2.4x (earnings normalizing). Chart setup: Death cross but MACD improving, RSI 56. Prior stop was $21.03. Score 6.2/10, moderate confidence.

What is the ACAD stock price target?

Take-profit target: $28.53 (+28.0% upside). Prior stop was $21.03. Stop-loss: $21.03.

What are the risks of investing in ACAD?

Concentration risk — Product: NUPLAZID and DAYBUE; Cyclical risk: PE expanding 2.4x (earnings normalizing); Leverage penalty (D/E 4.3): -1.5.

Is ACAD overvalued or undervalued?

ACADIA Pharmaceuticals Inc. trades at a P/E of 9.7 (forward 23.3). TrendMatrix value score: 7.2/10. Verdict: Sell.

What do analysts say about ACAD?

27 analysts cover ACAD with a consensus score of 4.0/5. Average price target: $32.

What does ACADIA Pharmaceuticals Inc. do?ACADIA Pharmaceuticals is a biopharmaceutical company commercializing two products: NUPLAZID (pimavanserin) for...

ACADIA Pharmaceuticals is a biopharmaceutical company commercializing two products: NUPLAZID (pimavanserin) for Parkinson's disease psychosis and DAYBUE (trofinetide) for Rett syndrome, with combined net product sales of $1,071.5 million in 2025. Both are the first and only FDA-approved drugs for their respective indications. The pipeline includes remlifanserin (ACP-204) for Alzheimer's disease psychosis in Phase 2 trials.

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