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STROSutro Biopharma, Inc.Sell4.9·$30.43+0.63%
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Sutro Biopharma, Inc. (STRO) Stock Analysis

Range Bound setup · Inst Constrain edge

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $30.43: Quality below floor (3.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 2.4:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality.

Sutro Biopharma, Inc. operates as an oncology company. The company develops site-specific and novel-format antibody drug conjugates (ADCs) that enables its proprietary integrated cell-free protein synthesis platform, XpressCF; and site-specific conjugation platform, XpressCF+.... Read more

$30.43+36.5% A.UpsideScore 4.9/10#166 of 258 Biotechnology
QualityF-score2 / 9FCF yield-21.12%
Stop $28.30Target $41.54(analyst − 13%)A.R:R 2.4:1
Analyst target$47.75+56.9%12 analysts
$41.54our TP
$30.43price
$47.75mean
$10
$61

Sell if holding. Engine safety override at $30.43: Quality below floor (3.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 2.4:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality. Chart setup: RSI 60 mid-range, Bollinger mid-band. Score 4.9/10, moderate confidence.

Passes 8/8 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity no date, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

Thesis

Rewards
No bull case signals
Risks
Quality below floor (3.2 < 4.0)
Value-trap signals (2/5): Margin compression (op margin -33.1%), Material insider selling (3 sells, 0.02% of cap)

Key Metrics

P/E (TTM)
P/E (Fwd)-4.4
Mkt Cap$504M
EV/EBITDA-3.9
Profit Mgn-154.2%
ROE
Rev Growth-16.5%
Beta1.52
DividendNone
Rating analysts20

Quality Signals

Piotroski F2/9

Options Flow

P/C0.25bullish
IV188%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

3 floor-breakers

Revenue shrinking — -16.5% YoY. Growth thesis broken unless recovery story develops.static

Revenue Growth
0.0
Declining revenue: -16%
Low model confidence on this dimension (33%).

Unprofitable operations — net margin -154.2%. Quality floor flags this regardless of sector context.static

Roa
0.0
Fcf Quality
0.0
Piotroski F
2.2
Moat
3.8
Current Ratio
9.9
Cash-burning: FCF -107% of revenueNo competitive moatWeak Piotroski F-Score: 2/9

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.0
Growth Rank
2.8
Value Rank
7.4
GatesMomentum 7.5>=5.5A.R:R 2.4 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY NO DATESEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Speculative
RSI
60 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $24.39Resistance $34.05

Price Targets

$28
$42
A.Upside+36.5%
A.R:R2.4:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (3.2 < 4.0)
! Value-trap signals (2/5): Margin compression (op margin -33.1%), Material insider selling (3 sells, 0.02% of cap)

Earnings

B
B
M
M
2/4 beats

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is STRO stock a buy right now?

Sell if holding. Engine safety override at $30.43: Quality below floor (3.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 2.4:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality. Chart setup: RSI 60 mid-range, Bollinger mid-band. Prior stop was $28.30. Score 4.9/10, moderate confidence.

What is the STRO stock price target?

Take-profit target: $41.54 (+36.5% upside). Prior stop was $28.30. Stop-loss: $28.30.

What are the risks of investing in STRO?

Quality below floor (3.2 < 4.0); Value-trap signals (2/5): Margin compression (op margin -33.1%), Material insider selling (3 sells, 0.02% of cap).

Is STRO overvalued or undervalued?

Sutro Biopharma, Inc. trades at a P/E of N/A (forward -4.4). TrendMatrix value score: 8.2/10. Verdict: Sell.

What do analysts say about STRO?

20 analysts cover STRO with a consensus score of 4.1/5. Average price target: $48.

What does Sutro Biopharma, Inc. do?Sutro Biopharma, Inc. operates as an oncology company. The company develops site-specific and novel-format antibody...

Sutro Biopharma, Inc. operates as an oncology company. The company develops site-specific and novel-format antibody drug conjugates (ADCs) that enables its proprietary integrated cell-free protein synthesis platform, XpressCF; and site-specific conjugation platform, XpressCF+. Its lead product candidate includes STRO-004, a tissue factor (TF) targeting ADC for the treatment of TF-expressing solid tumors, including non-small cell lung cancer, head and neck squamous cell carcinoma, cervical cancer, colorectal cancer, pancreatic ductal adenocarcinoma, endometrial cancer, and bladder cancer. The company also develops VAX-24 and Vax-31 pneumococcal conjugate vaccine candidates that is in Phase II/III clinical trials for the treatment of invasive pneumococcal disease in adults and adults and infants; and STRO-003, an ADC directed against an anti-receptor tyrosine kinase-like orphan receptor 1 (ROR1) for the treatment of solid tumors, such as triple negative breast cancer, non-small cell lung cancer, and ovarian cancer, as well as hematological cancers. Sutro Biopharma, Inc. has collaboration and license agreements with Vaxcyte to discover and develop vaccine candidates for the treatment or prophylaxis of infectious diseases; Tasly Biopharmaceuticals Co., Ltd. to develop and commercialize STRO-002 in Greater China; Ipsen to develop and commercialize STRO-003, an ADC targeting ROR1; and Astellas Pharma Inc. to develop immunostimulatory ADC. The company was formerly known as Fundamental Applied Biology, Inc. Sutro Biopharma, Inc. was incorporated in 2003 and is headquartered in South San Francisco, California.

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