SOPHiA GENETICS shows a confirmed technical breakout and favorable risk/reward asymmetry, but persistent cash burn, a Rule of 40 failure, and heavy insider selling activity weigh against the bullish technical setup.
Thesis pillars
- Elevated Options Hedging↑Improving
- Technical Breakout Golden Cross→Stable
- Cash Burn Rule Of 40 Failure→Stable
- +2 more pillars — see the Why tab for full reasoning
SOPHiA GENETICS SA (SOPH) Stock Analysis
Breakout setup · Inst Constrain edge
Healthcare · Health Information Services
Sell if holding. Engine safety override at $5.77: Quality below floor (3.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.5/10 and A.R:R 2.5:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum.
SOPHiA GENETICS SA operates as a cloud-native software technology company in the healthcare space. It offers SOPHiA DDM platform, a cloud-native software platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM... Read more
Sell if holding. Engine safety override at $5.77: Quality below floor (3.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.5/10 and A.R:R 2.5:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum. Chart setup: Golden cross, above all MAs, RSI 58, MACD bullish. Score 5.5/10, moderate confidence.
Passes 5/8 gates (favorable risk/reward ratio, no SEC red flags, news events none recent, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum and clean insider activity. Suitability: aggressive.
Recent developments
updated 2026-07-25Recent Developments — SOPHiA GENETICS SA
Latest news
- NEWS This Charles Schwab Analyst Is No Longer Bullish; Here Are Top 5 Downgrades For Monday — benzinga Jul 20, 2026 neutral
- NEWS This Urban Outfitters Analyst Turns Bullish; Here Are Top 5 Upgrades For Monday — benzinga Jul 20, 2026 neutral
- NEWS This Crane Analyst Begins Coverage On A Bullish Note; Here Are Top 5 Initiations For Monday — benzinga Jul 20, 2026 positive
- NEWS HC Wainwright & Co. Initiates Coverage On Sophia Genetics with Buy Rating, Announces Price Target of $12 — benzinga Jul 20, 2026 positive
Generated 2026-07-25T14:18:07Z.
Upcoming dated catalysts
Thesis
Key Metrics
Quality Signals
Options Flow
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.
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Rating Breakdown
3 floor-breakers
Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static
Unprofitable operations — net margin -99.7%. Quality floor flags this regardless of sector context.static
Momentum below the gate floor. Component breakdown shows what dragged the score down.static
Price Targets
Position Sizing
Risk Alerts
Earnings
Verdict History
Frequently Asked Questions
Sell if holding. Engine safety override at $5.77: Quality below floor (3.0 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.5/10 and A.R:R 2.5:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum. Chart setup: Golden cross, above all MAs, RSI 58, MACD bullish. Prior stop was $5.32. Score 5.5/10, moderate confidence.
Take-profit target: $7.65 (+33.7% upside). Prior stop was $5.32. Stop-loss: $5.32.
Quality below floor (3.0 < 4.0).
SOPHiA GENETICS SA trades at a P/E of N/A (forward -10.2). TrendMatrix value score: 7.9/10. Verdict: Sell.
10 analysts cover SOPH with a consensus score of 4.3/5. Average price target: $9.
What does SOPHiA GENETICS SA do?SOPHiA GENETICS SA operates as a cloud-native software technology company in the healthcare space. It offers SOPHiA DDM...
SOPHiA GENETICS SA operates as a cloud-native software technology company in the healthcare space. It offers SOPHiA DDM platform, a cloud-native software platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM platform and related solutions, applications, products, and services are used by hospitals, laboratories, and biopharmaceutical companies through its own sales force as well as distributors and industry collaborators in Switzerland, France, Italy, rest of Europe, North America, the United States, Latin America, and the Asia-pacific. The company has a partnership with Synnovis to bring blood-based cancer testing to patients in the United Kingdom. The company was incorporated in 2011 and is based in Rolle, Switzerland.