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SOPHSOPHiA GENETICS SASell5.7·$7.57-0.53%
SellModerate Confidence
Investment thesis

SOPHiA GENETICS shows a confirmed technical breakout and favorable risk/reward asymmetry, but persistent cash burn, a Rule of 40 failure, and heavy insider selling activity weigh against the bullish technical setup.

Thesis pillars

  • Elevated Options HedgingImproving
  • Technical Breakout Golden CrossImproving
  • Cash Burn Rule Of 40 FailureImproving
  • +2 more pillars — see the Why tab for full reasoning

Full reasoning →

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SOPHiA GENETICS SA (SOPH) Stock Analysis

Breakout setup

SellVALUE-TRAP 1/5GrowthQualityModerate Confidence

Healthcare · Health Information Services

Sell if holding. Engine safety override at $7.57: Quality below floor (3.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: Below-average business quality.

SOPHiA GENETICS SA operates as a cloud-native software technology company in the healthcare space. It offers SOPHiA DDM platform, a cloud-native software platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM... Read more

$7.57+9.5% A.UpsideScore 5.7/10#11 of 22 Health Information Services
QualityF-score6 / 9FCF yield-4.02%
Stop $7.04Target $8.29(analyst − 15%)A.R:R 0.6:1
Analyst target$9.75+28.8%4 analysts
$8.29our TP
$7.57price
$9.75mean
$14

Sell if holding. Engine safety override at $7.57: Quality below floor (3.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: Below-average business quality. Chart setup: Golden cross, above all MAs, RSI 69, MACD bullish. Score 5.7/10, moderate confidence.

Passes 6/9 gates (positive momentum, no SEC red flags, news events none recent, earnings proximity 82d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-08-13
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Nov 3, 202682d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Quality below floor (3.5 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-15.2
Mkt Cap$638M
EV/EBITDA-8.4
Profit Mgn-93.9%
ROE-101.2%
Rev Growth27.2%
Beta0.92
DividendNone
Rating analysts11

Quality Signals

Piotroski F6/9MoatNarrow

Options Flow

P/C1.00neutral

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers·1 ceiling hit

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.0
Value Rank
1.8
Growth Rank
8.2
Industry growth leader

Unprofitable operations — net margin -93.9%. Quality floor flags this regardless of sector context.static

Roe
0.0
Roa
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Rule Of 40
3.0
Moat
6.5
Piotroski F
6.7
Current Ratio
9.1
Gross Margin
9.3
Cash-burning: FCF -30% of revenueRule of 40: -3 (fail)
GatesA.R:R 0.6 < 1.5@spotMomentum 5.3<5.5 (soft — BUY_NOW allowed but watch)INSIDER 0.26%=MODERATEMomentum 5.3>=4.5No SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 82d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARBreakoutSuitability: Aggressive
RSI
69 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $5.42Resistance $7.88

Price Targets

$7
$8
A.Upside+9.5%
A.R:R0.6:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (3.5 < 4.0)
! asymmetry at 0.6 (below the engine's 1.5 threshold)@spot

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-11-03 (82d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is SOPH stock a buy right now?

Sell if holding. Engine safety override at $7.57: Quality below floor (3.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10. Specifically: Below-average business quality. Chart setup: Golden cross, above all MAs, RSI 69, MACD bullish. Prior stop was $7.04. Score 5.7/10, moderate confidence.

What is the SOPH stock price target?

Take-profit target: $8.29 (+9.5% upside). Prior stop was $7.04. Stop-loss: $7.04.

What are the risks of investing in SOPH?

Quality below floor (3.5 < 4.0).

Is SOPH overvalued or undervalued?

SOPHiA GENETICS SA trades at a P/E of N/A (forward -15.2). TrendMatrix value score: 5.7/10. Verdict: Sell.

What do analysts say about SOPH?

11 analysts cover SOPH with a consensus score of 4.3/5. Average price target: $10.

What does SOPHiA GENETICS SA do?SOPHiA GENETICS SA operates as a cloud-native software technology company in the healthcare space. It offers SOPHiA DDM...

SOPHiA GENETICS SA operates as a cloud-native software technology company in the healthcare space. It offers SOPHiA DDM platform, a cloud-native software platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM platform and related solutions, applications, products, and services are used by hospitals, laboratories, and biopharmaceutical companies through its own sales force as well as distributors and industry collaborators in Switzerland, France, Italy, rest of Europe, North America, the United States, Latin America, and the Asia-pacific. The company has a partnership with Synnovis to bring blood-based cancer testing to patients in the United Kingdom and a collaboration with AstraZeneca to develop, validate, and deploy two companion diagnostics (CDx) supporting precision oncology therapies. The company was incorporated in 2011 and is based in Rolle, Switzerland.

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