Monopar Therapeutics Inc. (MNPR) Stock Analysis
Healthcare · Biotechnology
Sell if holding. Engine safety override at $97.79: Quality below floor (1.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.0/10. Specifically: High short interest: 34%; Below-average business quality.
Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary... Read more
Sell if holding. Engine safety override at $97.79: Quality below floor (1.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.0/10. Specifically: High short interest: 34%; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Score 5.0/10, moderate confidence.
Passes 7/8 gates (positive momentum, clean insider activity, no SEC red flags, news boost analyst 0.60, earnings proximity 40d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: speculative.
Recent developments
updated 2026-07-05Recent Developments — Monopar Therapeutics Inc.
Latest news
- NEWS Monopar Says FDA Grants Rare Pediatric Disease Designation To ALXN1840, Late-Stage Candidate For Treatment Of Wilson Dis — benzinga Jun 30, 2026 positive
- NEWS BTIG Maintains Buy on Monopar Therapeutics, Raises Price Target to $117 — benzinga Jun 30, 2026 positive
- NEWS HC Wainwright & Co. Reiterates Buy on Monopar Therapeutics, Maintains $105 Price Target — benzinga Jun 29, 2026 positive
Generated 2026-07-05T09:50:25Z.
Upcoming dated catalysts
Thesis
Key Metrics
Quality Signals
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.
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Rating Breakdown
2 floor-breakers
Quality below the gate floor. Component breakdown shows what dragged the score down.static
Technicals below the gate floor. Component breakdown shows what dragged the score down.static
Price Targets
Position Sizing
Risk Alerts
Earnings
Verdict History
Frequently Asked Questions
Sell if holding. Engine safety override at $97.79: Quality below floor (1.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.0/10. Specifically: High short interest: 34%; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $90.94. Score 5.0/10, moderate confidence.
Take-profit target: $98.85 (+1.1% upside). Prior stop was $90.94. Stop-loss: $90.94.
Target reached (1.1% upside); Quality below floor (1.6 < 4.0); Value-trap signals (2/5): Margin compression (op margin -140.3%), High leverage (D/E 4.1).
Monopar Therapeutics Inc. trades at a P/E of N/A (forward -31.2). TrendMatrix value score: 5.0/10. Verdict: Sell.
19 analysts cover MNPR with a consensus score of 4.2/5. Average price target: $114.
What does Monopar Therapeutics Inc. do?Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the...
Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary humanized monoclonal antibody that is conjugated with different radioisotopes for the treatment of advanced solid tumors expressing urokinase plasminogen activator receptor; and MNPR-101-Zr, which is in phase 1 imaging and dosimetry clinical trial, a radiopharmaceutical imaging agent comprised of MNPR-101 conjugated to zirconium-89. It develops MNPR-101-Lu, a Phase1a stage radiotherapeutic comprised of MNPR-101 conjugated to actinium-225. The company has collaborations NorthStar to develop radio-immuno-therapeutics targeting severe COVID-19; Excel Diagnostics and Nuclear Oncology Center, for the investigational imaging agent MNPR-101-Zr and investigational therapeutic agent MNPR-101-Lu; license agreement with Alexion to develop and commercialize ALXN1840, a drug candidate for Wilson disease. The company was founded in 2014 and is headquartered in Wilmette, Illinois.