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GYREGyre Therapeutics, Inc.Sell5.3·$7.34+12.58%
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Gyre Therapeutics, Inc. (GYRE) Stock Analysis

Recovery setup

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Multiple concerning factors at $7.34: Value-trap signals (2/5): Margin compression (op margin -30.2%), Material insider selling (18 sells, 0.12% of cap); Below 200-MA, MA slope -3.2%/30d (confirmed downtrend).

Gyre Therapeutics, Inc., a pharmaceutical company, engages in the development and commercialization of small-molecule, anti-inflammatory, and anti-fibrotic drugs targeting organ fibrosis. The company offers ETUARY (Pirfenidone), an anti-fibrotic drug approved for the treatment... Read more

$7.34+116.2% A.UpsideScore 5.3/10#78 of 258 Biotechnology
QualityF-score9 / 9FCF yield1.17%
Stop $6.83Target $15.87(analyst − 15%)A.R:R 7.7:1
Analyst target$18.67+154.3%3 analysts
$15.87our TP
$7.34price
$18.67mean
$20

Sell if holding. Multiple concerning factors at $7.34: Value-trap signals (2/5): Margin compression (op margin -30.2%), Material insider selling (18 sells, 0.12% of cap); Below 200-MA, MA slope -3.2%/30d (confirmed downtrend). Chart setup: Death cross but MACD improving, RSI 74. Score 5.3/10, moderate confidence.

Passes 8/9 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 37d clear, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Mon, Aug 10, 202637d to earnings· next earnings call

Thesis

Rewards
Analyst upside: 116%
Risks
Below 200-MA, MA slope -3.2%/30d (confirmed downtrend)
Value-trap signals (2/5): Margin compression (op margin -30.2%), Material insider selling (18 sells, 0.12% of cap)

Key Metrics

P/E (TTM)
P/E (Fwd)122.3
Mkt Cap$818M
EV/EBITDA129.6
Profit Mgn-5.4%
ROE-3.1%
Rev Growth2.1%
Beta4.78
DividendNone
Rating analysts9

Quality Signals

Piotroski F9/9

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

1 floor-breaker

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.0
Support Resistance
0.1
Gap
5.0
52w Position
5.6
GatesDeath cross (50MA < 200MA)Momentum 6.0>=5.5A.R:R 7.7 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 37d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRecoverySuitability: Speculative
RSI
74 · Overbought
20D MA 50D MA 200D MADEATH CROSSSupport $5.71Resistance $7.36

Price Targets

$7
$16
A.Upside+116.2%
A.R:R7.7:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Analyst Consensus

Analysts9
Consensus4.2/5
Avg Target$19

Earnings

B
B
M
M
2/4 beats
Next Earnings2026-08-10 (37d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is GYRE stock a buy right now?

Sell if holding. Multiple concerning factors at $7.34: Value-trap signals (2/5): Margin compression (op margin -30.2%), Material insider selling (18 sells, 0.12% of cap); Below 200-MA, MA slope -3.2%/30d (confirmed downtrend). Chart setup: Death cross but MACD improving, RSI 74. Prior stop was $6.83. Score 5.3/10, moderate confidence.

What is the GYRE stock price target?

Take-profit target: $15.87 (+116.2% upside). Prior stop was $6.83. Stop-loss: $6.83.

What are the risks of investing in GYRE?

Below 200-MA, MA slope -3.2%/30d (confirmed downtrend); Value-trap signals (2/5): Margin compression (op margin -30.2%), Material insider selling (18 sells, 0.12% of cap).

Is GYRE overvalued or undervalued?

Gyre Therapeutics, Inc. trades at a P/E of N/A (forward 122.3). TrendMatrix value score: 6.0/10. Verdict: Sell.

What do analysts say about GYRE?

9 analysts cover GYRE with a consensus score of 4.2/5. Average price target: $19.

What does Gyre Therapeutics, Inc. do?Gyre Therapeutics, Inc., a pharmaceutical company, engages in the development and commercialization of small-molecule,...

Gyre Therapeutics, Inc., a pharmaceutical company, engages in the development and commercialization of small-molecule, anti-inflammatory, and anti-fibrotic drugs targeting organ fibrosis. The company offers ETUARY (Pirfenidone), an anti-fibrotic drug approved for the treatment of idiopathic pulmonary fibrosis; and under Phase 3 trials for the treatment of pneumoconiosis. It is also involved in the development of F351 (Hydronidone), a structural derivative of ETUARY under Phase 3 trials for the treatment of chronic hepatitis B (CHB)-associated liver fibrosis; and completed Phase 1 trials for the treatment of liver fibrosis associated with metabolic dysfunction-associated steatohepatitis. In addition, the company develops F573, which is in Phase 2 clinical trials for the treatment of acute/acute-on-chronic liver failure. Further, its preclinical products include F230 for the treatment of pulmonary arterial hypertension; and F528 to treat chronic obstructive pulmonary disease. Gyre Therapeutics, Inc. was founded in 2002 and is headquartered in San Diego, California. Gyre Therapeutics, Inc. operates as a subsidiary of GNI USA, Inc.

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