Skip to main content

Relay Therapeutics, Inc. (RLAY) Stock Analysis

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Biotechnology

Earnings in 5 days (2026-05-05). Expect elevated volatility around the report — consider waiting for post-earnings price action before new entries.

Sell if holding. Engine safety override at $12.92: Quality below floor (1.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.1/10 and A.R:R 2.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 18%; Below-average business quality; Negative price momentum.

Relay Therapeutics is a clinical-stage precision oncology company using its Dynamo Motion-Based Drug Design platform to develop small molecule inhibitors for cancer. The lead candidate zovegalisib (RLY-2608) is the first allosteric pan-mutant PI3Ka inhibitor, granted FDA... Read more

$12.92+41.4% A.UpsideScore 5.1/10#72 of 158 Biotechnology
Stop $12.02Target $18.27(analyst − 13%)A.R:R 2.8:1
Analyst target$21.00+62.5%12 analysts
$18.27our TP
$12.92price
$21.00mean
$25

Sell if holding. Engine safety override at $12.92: Quality below floor (1.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.1/10 and A.R:R 2.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 18%; Below-average business quality; Negative price momentum. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Score 5.1/10, moderate confidence.

Passes 5/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news boost analyst cluster(7), semi cycle peak clear). Fails on weak momentum and earnings proximity 5d<=7d. Suitability: aggressive.

Thesis

Rewards
Recent Analyst Cluster(7) detected in news
Risks
Concentration risk — Pipeline: zovegalisib
Quality below floor (1.5 < 4.0)
Value-trap signals (2/5): Material insider selling (17 sells, 0.06% of cap), Negative free cash flow

Key Metrics

P/E (TTM)
P/E (Fwd)-8.0
Mkt Cap$2.4B
EV/EBITDA-5.8
Profit Mgn0.0%
ROE-41.1%
Rev Growth
Beta1.58
DividendNone
Rating analysts18

Quality Signals

Piotroski F2/9

Options Flow

P/C0.48bullish
IV158%elevated
Max Pain$2-84.5% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHpipelinezovegalisib
    10-K Item 1A: 'We intend to develop zovegalisib and may develop our other current product candidates and future product candidates'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
2.2
Current Ratio
5.0
Moat
5.0
Cash-burning: FCF -929% of revenueNo competitive moatWeak Piotroski F-Score: 2/9Quality concerns

Volatile — 8.3% daily ATR makes tight stops impractical. Position-size conservatively.static

Volatility
0.0
Implied Vol
0.0
Debt Equity
0.0
Short Interest
1.7
Days To Cover
1.7
Max Pain Risk
3.0
Beta
4.7
Put Call
10.0
High short interest justified: 18%High IV: 158%Above max pain $2Concentration risks: 1 HIGH (10-K Item 1A — sized via position_sizing, validated via buy_confidence)

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Volume
0.0
Obv
1.0
Ma Position
6.0
Rsi
7.7
Uptrend pullback (RSI 38) - buy opportunityVolume distribution (falling OBV)Above 200-day MA

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
3.4
Value Rank
5.0
Growth Rank
5.0
GatesMomentum 2.9<4.5EARNINGS PROXIMITY 5d<=7dA.R:R 2.8 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS BOOST ANALYST CLUSTER(7)SEMI CYCLE PEAK CLEARSuitability: Aggressive
RSI
38 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $10.48Resistance $17.32

Price Targets

$12
$18
A.Upside+41.4%
A.R:R2.8:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.5 < 4.0)
! Value-trap signals (2/5): Material insider selling (17 sells, 0.06% of cap), Negative free cash flow
! Momentum score 2.9/10 — below 4.5 minimum

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-05-05 (5d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is RLAY stock a buy right now?

Sell if holding. Engine safety override at $12.92: Quality below floor (1.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.1/10 and A.R:R 2.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 18%; Below-average business quality; Negative price momentum. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Prior stop was $12.02. Score 5.1/10, moderate confidence.

What is the RLAY stock price target?

Take-profit target: $18.27 (+41.4% upside). Prior stop was $12.02. Stop-loss: $12.02.

What are the risks of investing in RLAY?

Concentration risk — Pipeline: zovegalisib; Quality below floor (1.5 < 4.0); Value-trap signals (2/5): Material insider selling (17 sells, 0.06% of cap), Negative free cash flow.

Is RLAY overvalued or undervalued?

Relay Therapeutics, Inc. trades at a P/E of N/A (forward -8.0). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about RLAY?

18 analysts cover RLAY with a consensus score of 4.4/5. Average price target: $21.

What does Relay Therapeutics, Inc. do?Relay Therapeutics is a clinical-stage precision oncology company using its Dynamo Motion-Based Drug Design platform to...

Relay Therapeutics is a clinical-stage precision oncology company using its Dynamo Motion-Based Drug Design platform to develop small molecule inhibitors for cancer. The lead candidate zovegalisib (RLY-2608) is the first allosteric pan-mutant PI3Ka inhibitor, granted FDA Breakthrough Therapy Designation in February 2026, with a global Phase 3 registrational trial (ReDiscover-2) underway for HR+/HER2- advanced breast cancer. The company has no approved products and no revenue from product sales.

Related stocks: INCY (Incyte Corporation) · HRMY (Harmony Biosciences Holdings, I) · AUPH (Aurinia Pharmaceuticals Inc) · NVAX (Novavax, Inc.) · CPRX (Catalyst Pharmaceuticals, Inc.)