Regeneron has beaten earnings estimates in all four of the last four quarters with an average surprise of 22%, trades at a forward price-to-earnings of 11.4x with 22% analyst upside, and maintains strong net margins of 30% — but faces declining earnings estimates, weak revenue growth, and near-term technical weakness from a death cross, creating a fundamentally sound but momentum-challenged setup.
Thesis pillars
- Strong Margins And Financial Health→Stable
- Perfect Earnings Beat Streak Quality→Stable
- Attractive Valuation Versus Peers→Stable
- +1 more pillar — see the Why tab for full reasoning
Regeneron Pharmaceuticals, Inc. (REGN) Stock Analysis
Recovery setup
Healthcare · Biotechnology
Sell if holding. Multiple concerning factors at $636.00: Leverage penalty (D/E 8.6): -1.5; Earnings estimates trending DOWN.
Regeneron Pharmaceuticals generated $14.3 billion in total revenues in 2025, driven by U.S. EYLEA HD and EYLEA net product sales (31% of revenues) and Sanofi collaboration revenue from Dupixent (41% of revenues). The company has multiple approved products spanning ophthalmology,... Read more
Sell if holding. Multiple concerning factors at $636.00: Leverage penalty (D/E 8.6): -1.5; Earnings estimates trending DOWN. Chart setup: Death cross but MACD improving, RSI 64. Score 5.9/10, moderate confidence.
Passes 7/7 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity 31d clear, semi cycle peak clear, materials cycle peak clear). Suitability: moderate.
Recent developments
updated 2026-06-29Recent Developments — Regeneron Pharmaceuticals, Inc.
Latest news
- NEWS Regeneron Stock Tumbles on Earnings. Upcoming Data Matter More for the Stock. - Barron's — Barron's negative
- NEWS Regeneron Slumps On An Unexpected Setback For Its Bread-And-Butter Drug - Investor's Business Daily — Investor's Business Daily negative
- NEWS Regeneron Slumps On Unexpected Eylea Setback - Investor's Business Daily — Investor's Business Daily negative
- NEWS Regeneron Pharmaceuticals Inc Stock (REGN) Moved Down by 7.82% on Apr 29: Facts Behind the Movement - TradingKey — TradingKey negative
- NEWS Earnings call transcript: Regeneron Q1 2026 beats estimates, stock dips - Investing.com — Investing.com positive
Generated 2026-06-30T00:04:05Z.
Upcoming dated catalysts
Thesis
Key Metrics
Quality Signals
Options Flow
Concentration Risks(10-K Item 1A)
- MEDIUMProductEYLEA HD and EYLEA31%10-K Item 1A: 'our aggregate EYLEA HD and EYLEA net product sales in the United States represented 31%...of our total revenues'
- MEDIUMcounterpartySanofi41%10-K Item 1A: 'Sanofi collaboration revenue (most of which is attributable to our share of profits from the commercialization of Dupixent) represented 41%...of our total revenues'
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.
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Rating Breakdown
2 floor-breakers
Technicals below the gate floor. Component breakdown shows what dragged the score down.static
Growth below the gate floor. Component breakdown shows what dragged the score down.static
Price Targets
Position Sizing
Analyst Consensus
Earnings
Verdict History
Frequently Asked Questions
Sell if holding. Multiple concerning factors at $636.00: Leverage penalty (D/E 8.6): -1.5; Earnings estimates trending DOWN. Chart setup: Death cross but MACD improving, RSI 64. Prior stop was $602.25. Score 5.9/10, moderate confidence.
Take-profit target: $749.98 (+18.7% upside). Prior stop was $602.25. Stop-loss: $602.25.
Leverage penalty (D/E 8.6): -1.5; Earnings estimates trending DOWN; Weak growth.
Regeneron Pharmaceuticals, Inc. trades at a P/E of 15.5 (forward 11.8). TrendMatrix value score: 7.2/10. Verdict: Sell.
38 analysts cover REGN with a consensus score of 3.9/5. Average price target: $833.
What does Regeneron Pharmaceuticals, Inc. do?Regeneron Pharmaceuticals generated $14.3 billion in total revenues in 2025, driven by U.S. EYLEA HD and EYLEA net...
Regeneron Pharmaceuticals generated $14.3 billion in total revenues in 2025, driven by U.S. EYLEA HD and EYLEA net product sales (31% of revenues) and Sanofi collaboration revenue from Dupixent (41% of revenues). The company has multiple approved products spanning ophthalmology, immunology, oncology, and rare diseases, partnering with Sanofi and Bayer for select commercialization outside the US.