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Rapport Therapeutics, Inc. (RAPP) Stock Analysis

SellModerate Confidence

Healthcare · Biotechnology

Earnings in 7 days (2026-05-07). Expect elevated volatility around the report — consider waiting for post-earnings price action before new entries.

Sell if holding. Engine safety override at $33.12: Quality below floor (1.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.8/10 and A.R:R 3.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 11%; Below-average business quality; Negative price momentum.

Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. The company's lead product candidate... Read more

$33.12+40.6% A.UpsideScore 4.8/10#97 of 158 Biotechnology
Stop $30.85Target $46.63(analyst − 13%)A.R:R 3.4:1
Analyst target$53.60+61.8%10 analysts
$46.63our TP
$33.12price
$53.60mean
$80

Sell if holding. Engine safety override at $33.12: Quality below floor (1.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.8/10 and A.R:R 3.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 11%; Below-average business quality; Negative price momentum. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Score 4.8/10, moderate confidence.

Passes 5/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear). Fails on weak momentum and earnings proximity 7d<=7d. Suitability: aggressive.

Thesis

Rewards
No bull case signals
Risks
Quality below floor (1.4 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-7.9
Mkt Cap$1.6B
EV/EBITDA-8.8
Profit Mgn0.0%
ROE-28.2%
Rev Growth
Beta
DividendNone
Rating analysts16

Quality Signals

Piotroski F2/9

Options Flow

P/C1.11bearish
IV110%elevated
Max Pain$13-62.3% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

3 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
2.2
Current Ratio
5.0
Moat
5.0
Cash-burning (FCF negative)No competitive moatWeak Piotroski F-Score: 2/9Quality concerns

Volatile — 6.0% daily ATR makes tight stops impractical. Position-size conservatively.static

Days To Cover
0.0
Volatility
0.0
Implied Vol
0.0
Debt Equity
2.6
Max Pain Risk
3.0
Short Interest
4.3
Put Call
5.9
High IV: 110%Above max pain $12

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Volume
0.0
Obv
1.0
Rsi
5.5
Ma Position
6.0
Volume distribution (falling OBV)Above 200-day MA
GatesMomentum 2.5<4.5EARNINGS PROXIMITY 7d<=7dA.R:R 3.4 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARSuitability: Aggressive
RSI
46 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $30.74Resistance $40.92

Price Targets

$31
$47
A.Upside+40.8%
A.R:R3.4:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.4 < 4.0)
! Momentum score 2.5/10 — below 4.5 minimum
! EARNINGS_PROXIMITY:7d<=7d

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-05-07 (7d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is RAPP stock a buy right now?

Sell if holding. Engine safety override at $33.12: Quality below floor (1.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.8/10 and A.R:R 3.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 11%; Below-average business quality; Negative price momentum. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Prior stop was $30.85. Score 4.8/10, moderate confidence.

What is the RAPP stock price target?

Take-profit target: $46.63 (+40.6% upside). Prior stop was $30.85. Stop-loss: $30.85.

What are the risks of investing in RAPP?

Quality below floor (1.4 < 4.0).

Is RAPP overvalued or undervalued?

Rapport Therapeutics, Inc. trades at a P/E of N/A (forward -7.9). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about RAPP?

16 analysts cover RAPP with a consensus score of 4.3/5. Average price target: $54.

What does Rapport Therapeutics, Inc. do?Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and...

Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. The company's lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. It also develops nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and migraine; and a9a10 nAChR for the treatment of hearing/vestibular disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts.

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