Skip to main content

Natera, Inc. (NTRA) Stock Analysis

Range Bound setup

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Diagnostics & Research

Sell if holding. Momentum 3.7/10 is below the 5.0 floor at $203.70 — engine's falling-knife protection flags exit rather than catching a breakdown. Specifics: Concentration risk — Product: Panorama NIPT, Horizon, and Signatera (majority of revenue); Concentration risk — Counterparty: DNAnexus (sole cloud platform for algorithms).

Natera is a diagnostics company commercializing cfDNA-based tests for oncology (Signatera MRD), women's health (Panorama NIPT, Horizon carrier screening), and organ health (Prospera transplant rejection). Revenue reached $2,306.1M in 2025 ($2,295.8M product revenue), processing... Read more

$203.70+19.8% A.UpsideScore 5.7/10#6 of 26 Diagnostics & Research
QualityF-score8 / 9FCF yield0.49%
Stop $182.32Target $234.80(analyst − 10%)A.R:R 1.7:1
Analyst target$260.89+28.1%18 analysts
$234.80our TP
$203.70price
$260.89mean
$300

Sell if holding. Momentum 3.7/10 is below the 5.0 floor at $203.70 — engine's falling-knife protection flags exit rather than catching a breakdown. Specifics: Concentration risk — Product: Panorama NIPT, Horizon, and Signatera (majority of revenue); Concentration risk — Counterparty: DNAnexus (sole cloud platform for algorithms). Chart setup: RSI 51 mid-range, Bollinger mid-band. Score 5.7/10, moderate confidence.

Passes 6/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity 78d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: aggressive.

Recent Developments — Natera, Inc.

Generated 2026-05-20T20:21:21Z.

Thesis

Rewards
Sector modifier (Healthcare): +0.5
Strong growth profile
Risks
Concentration risk — Product: Panorama NIPT, Horizon, and Signatera (majority of revenue)
Concentration risk — Counterparty: DNAnexus (sole cloud platform for algorithms)
V7 low-quality RISK_OFF penalty: -0.5 (Q=4.7)

Key Metrics

P/E (TTM)
P/E (Fwd)-518.5
Mkt Cap$28.1B
EV/EBITDA-101.8
Profit Mgn-9.0%
ROE-15.0%
Rev Growth38.8%
Beta1.57
DividendNone
Rating analysts28

Quality Signals

Piotroski F8/9MoatNarrow

Options Flow

P/C2.34bearish
IV58%elevated
Max Pain$130-36.2% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHProductPanorama NIPT, Horizon, and Signatera (majority of revenue)
    10-K Item 1A: 'the significant majority of our revenues are derived from sales of our Panorama NIPT, our Horizon carrier screening, or HCS, test, and our Signatera test'
  • HIGHcounterpartyDNAnexus (sole cloud platform for algorithms)
    10-K Item 1: 'We do not have any backup cloud platform, server or other means to host our algorithms, and may be unable to find and implement an alternative platform that is satisfactory for our needs on commercially reasonable terms, in a timely manner, or at all'

Material Events(8-K, last 90d)

  • 2026-04-01Item 5.02LOW
    Eric Rubin appointed as Class I director to the Board effective March 26, 2026; Board expanded from ten to eleven members. Dr. Rubin joins Nominating, Corporate Governance and Compliance Committee. No arrangement cited for selection.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

2 floor-breakers·2 ceiling hits

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Value Rank
0.8
Quality Rank
1.8
Growth Rank
8.5
Industry growth leader

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Macd
0.0
Volume
1.8
Ma Position
2.2
Rsi
4.5
Obv
10.0
Volume accumulation (rising OBV)Below 200-MA but MA still rising (+3.9%/30d) — pullback in uptrend, not confirmed weakness
GatesMomentum 3.7<4.5A.R:R 1.7 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY 78d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Aggressive
RSI
51 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $184.81Resistance $221.56

Price Targets

$182
$235
A.Upside+15.3%
A.R:R1.7:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeRisk-Off

Risk Alerts

! NEWS_MOD=-1: HOLD_IF_HOLDING → SELL_IF_HOLDING
! Momentum score 3.7/10 — below 4.5 minimum

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-06 (78d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is NTRA stock a buy right now?

Sell if holding. Momentum 3.7/10 is below the 5.0 floor at $203.70 — engine's falling-knife protection flags exit rather than catching a breakdown. Specifics: Concentration risk — Product: Panorama NIPT, Horizon, and Signatera (majority of revenue); Concentration risk — Counterparty: DNAnexus (sole cloud platform for algorithms). Chart setup: RSI 51 mid-range, Bollinger mid-band. Prior stop was $182.32. Score 5.7/10, moderate confidence.

What is the NTRA stock price target?

Take-profit target: $234.80 (+19.8% upside). Prior stop was $182.32. Stop-loss: $182.32.

What are the risks of investing in NTRA?

Concentration risk — Product: Panorama NIPT, Horizon, and Signatera (majority of revenue); Concentration risk — Counterparty: DNAnexus (sole cloud platform for algorithms); V7 low-quality RISK_OFF penalty: -0.5 (Q=4.7).

Is NTRA overvalued or undervalued?

Natera, Inc. trades at a P/E of N/A (forward -518.5). TrendMatrix value score: 5.5/10. Verdict: Sell.

What do analysts say about NTRA?

28 analysts cover NTRA with a consensus score of 4.3/5. Average price target: $261.

What does Natera, Inc. do?Natera is a diagnostics company commercializing cfDNA-based tests for oncology (Signatera MRD), women's health...

Natera is a diagnostics company commercializing cfDNA-based tests for oncology (Signatera MRD), women's health (Panorama NIPT, Horizon carrier screening), and organ health (Prospera transplant rejection). Revenue reached $2,306.1M in 2025 ($2,295.8M product revenue), processing approximately 3.5 million tests. The company markets tests through a direct U.S. sales force and 100+ international lab/distribution partners.

Related stocks: VCYT (Veracyte, Inc.) · SHC (Sotera Health Company) · GH (Guardant Health, Inc.) · MEDP (Medpace Holdings, Inc.) · WAT (Waters Corporation)