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ERASErasca, Inc.Sell4.4·$18.97+2.71%
SellModerate Confidence
Investment thesis

Erasca is a cash-burning early-stage biotechnology company with all value concentrated in two Phase 1 clinical programs and a quality profile well below the minimum acceptable floor; the stock has broken out technically — above all key moving averages with a golden cross, RSI at 70, and rising institutional interest — and offers 26.6% headroom to the analyst target at a roughly 3.8-to-1 favorable risk/reward, but the absence of commercial operations, negative free cash flow, and a large recent earnings miss mean quality risk dominates the setup.

Thesis pillars

  • Favorable Upside AsymmetryStable
  • Quality Below Minimum FloorStable
  • Clinical Pipeline ConcentrationStable
  • +1 more pillar — see the Why tab for full reasoning

Full reasoning →

Open full analysis

Erasca, Inc. (ERAS) Stock Analysis

SellVALUE-TRAP 3/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $18.97: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 4.4/10. Specifically: High short interest: 11%; Below-average business quality.

Erasca is a clinical-stage precision oncology company targeting RAS/MAPK pathway-driven cancers, with two Phase 1 clinical programs — ERAS-0015 (pan-RAS molecular glue) and ERAS-4001 (pan-KRAS inhibitor) — and no approved products or revenue. The company reported a net loss of... Read more

$18.97-1.8% A.UpsideScore 4.4/10#201 of 253 Biotechnology
QualityF-score4 / 9FCF yield-3.70%
Stop $17.53Target $18.51(resistance)A.R:R -0.2:1
Analyst target$21.00+10.7%10 analysts
$18.51our TP
$18.97price
$21.00mean
$12
$30

Sell if holding. Engine safety override at $18.97: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 4.4/10. Specifically: High short interest: 11%; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Score 4.4/10, moderate confidence.

Passes 7/8 gates (positive momentum, clean insider activity, no SEC red flags, news events none recent, earnings proximity 38d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-07

Recent Developments — Erasca, Inc.

Generated 2026-07-07T11:21:38Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Wed, Aug 12, 202638d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Pipeline: ERAS-0015 and ERAS-4001 Phase 1 programs
Target reached (-3.1% upside)
Quality below floor (1.6 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-32.1
Mkt Cap$5.7B
EV/EBITDA-42.4
Profit Mgn0.0%
ROE-69.9%
Rev Growth
Beta0.67
DividendNone
Rating analysts17

Quality Signals

Piotroski F4/9

Options Flow

P/C0.18bullish
IV110%elevated

Concentration Risks(10-K Item 1A)

  • HIGHpipelineERAS-0015 and ERAS-4001 Phase 1 programs
    10-K Item 1A: 'AURORAS-1 and BOREALIS-1 Phase 1 trials for ERAS-0015 and ERAS-4001 ... all of our other programs are still in the preclinical or discovery stage'
  • MEDIUMSupplierJoyo
    10-K Item 1: 'ERAS-0015, which we license from Guangzhou Joyo Pharmatech Co., Ltd. (Joyo)'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

Not investment advice. TrendMatrix is not a registered investment adviser. Our content is for informational and educational purposes only. Consult your own licensed investment adviser, broker, or tax professional before making any investment decision.

Conflicts and positions. The TrendMatrix editorial team frequently holds personal long-term positions in securities discussed. We disclose positions held at the time of publication on each piece. We maintain a trading-window policy: we do not initiate or close positions in the same direction as a TrendMatrix publication within 24 hours before or 72 hours after publication.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

4 floor-breakers

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
4.4
Moat
4.8
Current Ratio
5.0
Cash-burning (FCF negative)No competitive moatQuality concerns

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Support Resistance
0.1
Bollinger
0.6
52w Position
5.5

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
1.1
Value Rank
5.0
Growth Rank
5.0
GatesA.R:R -0.2=NEGATIVEMomentum 7.0>=5.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 38d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Speculative
RSI
78 · Overbought
20D MA 50D MA 200D MAGOLDEN CROSSSupport $11.80Resistance $18.89

Price Targets

$18
$19
A.Upside-2.4%
A.R:R-0.2:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Target reached (-3.1% upside)
! Quality below floor (1.6 < 4.0)
! Value-trap signals (3/5): Margin compression (op margin -8.2%), Material insider selling (3 sells, 0.03% of cap), Negative free cash flow

Earnings

M
M
M
M
0/4 beats
Next Earnings2026-08-12 (38d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is ERAS stock a buy right now?

Sell if holding. Engine safety override at $18.97: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 4.4/10. Specifically: High short interest: 11%; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $17.53. Score 4.4/10, moderate confidence.

What is the ERAS stock price target?

Take-profit target: $18.51 (-1.8% upside). Prior stop was $17.53. Stop-loss: $17.53.

What are the risks of investing in ERAS?

Concentration risk — Pipeline: ERAS-0015 and ERAS-4001 Phase 1 programs; Target reached (-3.1% upside); Quality below floor (1.6 < 4.0).

Is ERAS overvalued or undervalued?

Erasca, Inc. trades at a P/E of N/A (forward -32.1). TrendMatrix value score: 4.0/10. Verdict: Sell.

What do analysts say about ERAS?

17 analysts cover ERAS with a consensus score of 4.1/5. Average price target: $21.

What does Erasca, Inc. do?Erasca is a clinical-stage precision oncology company targeting RAS/MAPK pathway-driven cancers, with two Phase 1...

Erasca is a clinical-stage precision oncology company targeting RAS/MAPK pathway-driven cancers, with two Phase 1 clinical programs — ERAS-0015 (pan-RAS molecular glue) and ERAS-4001 (pan-KRAS inhibitor) — and no approved products or revenue. The company reported a net loss of $124.5 million for 2025 and an accumulated deficit of $892.2 million as of December 31, 2025.

Related stocks: CRMD (CorMedix Inc.) · ZVRA (Zevra Therapeutics, Inc.) · AUPH (Aurinia Pharmaceuticals Inc) · INCY (Incyte Corporation) · HRMY (Harmony Biosciences Holdings, I)
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