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Charles River Laboratories Inte (CRL) Stock Analysis

Falling Knife setup

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Diagnostics & Research

Sell if holding. Engine safety override at $149.93: Quality below floor (3.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 2.2:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum; Below long-term trend.

Charles River Laboratories is a full-service drug development partner serving pharmaceutical and biotech companies through three segments: RMS (21.1% of 2025 revenue), DSA (59.8%), and Manufacturing Solutions (19.1%). Total revenue was $4.0 billion in 2025, with the company... Read more

$149.93+25.3% A.UpsideScore 4.9/10#22 of 26 Diagnostics & Research
QualityF-score6 / 9FCF yield7.06%
Stop $144.94Target $187.92(analyst − 10%)A.R:R 2.2:1
Analyst target$208.80+39.3%15 analysts
$187.92our TP
$149.93price
$208.80mean
$135
$265

Sell if holding. Engine safety override at $149.93: Quality below floor (3.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 2.2:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum; Below long-term trend. Chart setup: Death cross, below all MAs, RSI 37, MACD bearish. Score 4.9/10, moderate confidence.

Passes 6/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity 78d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: aggressive.

Recent Developments — Charles River Laboratories Inte

Generated 2026-05-20T21:06:21Z.

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Supplier: non-human primate supply
Quality below floor (3.4 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)12.2
Mkt Cap$7.2B
EV/EBITDA11.4
Profit Mgn-4.6%
ROE-5.9%
Rev Growth1.2%
Beta1.45
DividendNone
Rating analysts24

Quality Signals

Piotroski F6/9

Options Flow

P/C0.54bullish
IV54%elevated
Max Pain$125-16.6% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHSuppliernon-human primate supply
    10-K Item 1A: 'Several of our product and service offerings, including our non-human primate supply, are dependent on a limited source of supply that, when interrupted, adversely affects our business.'

Material Events(8-K, last 90d)

  • 2026-02-18Item 5.02MEDIUM
    Glenn Coleman appointed as Corporate EVP and CFO with tentative start date April 6, 2026. Joins from Premier, Inc. where he served as CFO and Chief Administrative Officer. Named successor with start date; prior CFO not mentioned.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Growth Rank
0.4
Quality Rank
2.5
Value Rank
8.1

Growth below the gate floor. Component breakdown shows what dragged the score down.static

Revenue Growth
2.8
Low model confidence on this dimension (33%).

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Macd
0.0
Obv
1.0
Ma Position
2.2
Rsi
3.5
Volume
8.7
Volume distribution (falling OBV)Below 200-MA but MA still rising (+1.2%/30d) — pullback in uptrend, not confirmed weakness

Unprofitable operations — net margin -4.6%. Quality floor flags this regardless of sector context.static

Roe
0.0
Net Margin
0.0
Roa
2.8
Gross Margin
2.9
Moat
3.1
Current Ratio
5.1
Operating Margin
6.4
Piotroski F
6.7
No competitive moat
GatesMomentum 3.1<4.5A.R:R 2.2 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY 78d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARFalling KnifeSuitability: Aggressive
RSI
37 · Neutral
20D MA 50D MA 200D MADEATH CROSSSupport $149.42Resistance $194.57

Price Targets

$145
$188
A.Upside+25.3%
A.R:R2.2:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (3.4 < 4.0)
! Momentum score 3.1/10 — below 4.5 minimum

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-08-05 (78d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is CRL stock a buy right now?

Sell if holding. Engine safety override at $149.93: Quality below floor (3.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 2.2:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum; Below long-term trend. Chart setup: Death cross, below all MAs, RSI 37, MACD bearish. Prior stop was $144.94. Score 4.9/10, moderate confidence.

What is the CRL stock price target?

Take-profit target: $187.92 (+25.3% upside). Prior stop was $144.94. Stop-loss: $144.94.

What are the risks of investing in CRL?

Concentration risk — Supplier: non-human primate supply; Quality below floor (3.4 < 4.0).

Is CRL overvalued or undervalued?

Charles River Laboratories Inte trades at a P/E of N/A (forward 12.2). TrendMatrix value score: 8.4/10. Verdict: Sell.

What do analysts say about CRL?

24 analysts cover CRL with a consensus score of 3.9/5. Average price target: $209.

What does Charles River Laboratories Inte do?Charles River Laboratories is a full-service drug development partner serving pharmaceutical and biotech companies...

Charles River Laboratories is a full-service drug development partner serving pharmaceutical and biotech companies through three segments: RMS (21.1% of 2025 revenue), DSA (59.8%), and Manufacturing Solutions (19.1%). Total revenue was $4.0 billion in 2025, with the company serving most global pharmaceutical companies and biotechnology clients. It is the largest provider of outsourced non-clinical safety assessment services worldwide.

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