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NUVBNuvation Bio Inc.Sell5.2·$5.04+2.44%
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Nuvation Bio Inc. (NUVB) Stock Analysis

Recovery setup

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $5.04: Risk below floor (2.5 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 7.5:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Elevated put/call ratio: 2.50; Below-average business quality.

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It... Read more

$5.04+113.1% A.UpsideScore 5.2/10#86 of 157 Biotechnology
QualityF-score6 / 9FCF yield-5.84%
Stop $4.68Target $10.73(analyst − 13%)A.R:R 7.5:1
Analyst target$12.33+144.7%9 analysts
$10.73our TP
$5.04price
$12.33mean
$20

Sell if holding. Engine safety override at $5.04: Risk below floor (2.5 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 7.5:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Elevated put/call ratio: 2.50; Below-average business quality. Chart setup: Death cross but MACD improving, RSI 58. Score 5.2/10, moderate confidence.

Passes 8/8 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 52d clear, semi cycle peak clear, materials cycle peak clear). Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-15
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 6, 202652d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Risk below floor (2.5 < 3.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-82.0
Mkt Cap$1.7B
EV/EBITDA-9.4
Profit Mgn-102.1%
ROE-39.5%
Rev Growth2598.7%
Beta1.56
DividendNone
Rating analysts17

Quality Signals

Piotroski F6/9MoatNarrow

Options Flow

P/C2.50bearish
IV85%elevated
Max Pain$18+247.2% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers

Volatile — 7.7% daily ATR makes tight stops impractical. Position-size conservatively.static

Days To Cover
0.0
Volatility
0.0
Put Call
0.0
Implied Vol
0.0
Short Interest
0.9
Beta
4.8
Debt Equity
6.9
Max Pain Risk
7.0
High short interest justified: 26%Elevated put/call: 2.50High IV: 84%

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

52w Position
0.3
Bollinger
2.0
Support Resistance
3.9
Gap
5.0
GatesMomentum 5.8>=5.5A.R:R 7.5 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 52d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRecoverySuitability: Aggressive
RSI
58 · Neutral
20D MA 50D MA 200D MADEATH CROSSSupport $4.07Resistance $5.64

Price Targets

$5
$11
A.Upside+112.9%
A.R:R7.5:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Risk below floor (2.5 < 3.0)

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-06 (52d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is NUVB stock a buy right now?

Sell if holding. Engine safety override at $5.04: Risk below floor (2.5 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 7.5:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Elevated put/call ratio: 2.50; Below-average business quality. Chart setup: Death cross but MACD improving, RSI 58. Prior stop was $4.68. Score 5.2/10, moderate confidence.

What is the NUVB stock price target?

Take-profit target: $10.73 (+113.1% upside). Prior stop was $4.68. Stop-loss: $4.68.

What are the risks of investing in NUVB?

Risk below floor (2.5 < 3.0).

Is NUVB overvalued or undervalued?

Nuvation Bio Inc. trades at a P/E of N/A (forward -82.0). TrendMatrix value score: 6.2/10. Verdict: Sell.

What do analysts say about NUVB?

17 analysts cover NUVB with a consensus score of 4.1/5. Average price target: $12.

What does Nuvation Bio Inc. do?Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer...

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1-mutant astrocytoma with safusidenib against placebo. The company was founded in 2018 and is headquartered in New York, New York.

Related stocks: AUPH (Aurinia Pharmaceuticals Inc) · HALO (Halozyme Therapeutics, Inc.) · AAPG (Ascentage Pharma Group Internat) · INVA (Innoviva, Inc.) · ADMA (ADMA Biologics Inc)
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