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JBIOJade Biosciences, Inc.Sell5.5·$21.51-1.38%
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Jade Biosciences, Inc. (JBIO) Stock Analysis

Inst Constrain edge

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $21.51: Quality below floor (2.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.5/10 and A.R:R 6.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 10%; Elevated put/call ratio: 32.75; Below-average business quality.

Jade Biosciences, Inc. operates as a biotechnology company that develops therapies for inflammation and immunology indications in patients living with autoimmune diseases. It develops JADE101, a monoclonal antibody to block the A PRoliferation Inducing Ligand protein, which is... Read more

$21.51+96.2% A.UpsideScore 5.5/10#60 of 258 Biotechnology
QualityF-score4 / 9FCF yield
Stop $20.00Target $42.20(analyst − 13%)A.R:R 6.4:1
Analyst target$48.50+125.5%8 analysts
$42.20our TP
$21.51price
$48.50mean
$74

Sell if holding. Engine safety override at $21.51: Quality below floor (2.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.5/10 and A.R:R 6.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 10%; Elevated put/call ratio: 32.75; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Score 5.5/10, moderate confidence.

Passes 7/7 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity 40d clear, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-05

Recent Developments — Jade Biosciences, Inc.

Generated 2026-07-05T10:00:59Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 13, 202640d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Quality below floor (2.5 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-9.4
Mkt Cap$1.3B
EV/EBITDA
Profit Mgn0.0%
ROE
Rev Growth
Beta
DividendNone
Rating analysts16

Quality Signals

Piotroski F4/9MoatNarrow

Options Flow

P/C32.75bearish
IV115%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

3 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Piotroski F
4.4
Current Ratio
5.0
Moat
5.5
Quality concerns

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
News Activity
5.0
Earnings concerns: 1B/3M

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Support Resistance
2.1
Bollinger
2.5
Gap
5.0
52w Position
5.4
GatesMomentum 5.9>=5.5A.R:R 6.4 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY 40d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Speculative
RSI
77 · Overbought
20D MA 50D MA 200D MAGOLDEN CROSSSupport $14.28Resistance $23.49

Price Targets

$20
$42
A.Upside+96.2%
A.R:R6.4:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (2.5 < 4.0)

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-13 (40d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is JBIO stock a buy right now?

Sell if holding. Engine safety override at $21.51: Quality below floor (2.5 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.5/10 and A.R:R 6.4:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 10%; Elevated put/call ratio: 32.75; Below-average business quality. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $20.00. Score 5.5/10, moderate confidence.

What is the JBIO stock price target?

Take-profit target: $42.20 (+96.2% upside). Prior stop was $20.00. Stop-loss: $20.00.

What are the risks of investing in JBIO?

Quality below floor (2.5 < 4.0).

Is JBIO overvalued or undervalued?

Jade Biosciences, Inc. trades at a P/E of N/A (forward -9.4). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about JBIO?

16 analysts cover JBIO with a consensus score of 4.4/5. Average price target: $49.

What does Jade Biosciences, Inc. do?Jade Biosciences, Inc. operates as a biotechnology company that develops therapies for inflammation and immunology...

Jade Biosciences, Inc. operates as a biotechnology company that develops therapies for inflammation and immunology indications in patients living with autoimmune diseases. It develops JADE101, a monoclonal antibody to block the A PRoliferation Inducing Ligand protein, which is in phase 1 clinical trial. The company also develops JADE201 and JADE-003, which are in preclinical development stage. Jade Biosciences, Inc. has a collaboration agreement with Paragon Therapeutics, Inc. Jade Biosciences, Inc. is based in Waltham, Massachusetts.

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