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CBIOCrescent Biopharma, Inc.Sell4.8·$17.09+0.06%
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Crescent Biopharma, Inc. (CBIO) Stock Analysis

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $17.09: Risk below floor (2.4 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.8/10 and A.R:R 3.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 28%; Below-average business quality; Negative price momentum.

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002,... Read more

$17.09+57.8% A.UpsideScore 4.8/10#175 of 258 Biotechnology
QualityF-score4 / 9FCF yield
Stop $16.00Target $26.97(analyst − 13%)A.R:R 3.9:1
Analyst target$31.00+81.4%5 analysts
$26.97our TP
$17.09price
$31.00mean
$35

Sell if holding. Engine safety override at $17.09: Risk below floor (2.4 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.8/10 and A.R:R 3.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 28%; Below-average business quality; Negative price momentum. Chart setup: No clear chart pattern; technical signals are mixed. Score 4.8/10, moderate confidence.

Passes 6/8 gates (favorable risk/reward ratio, no SEC red flags, news events none recent, earnings proximity no date, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-05

Recent Developments — Crescent Biopharma, Inc.

Latest news

Generated 2026-07-05T09:50:25Z.

Thesis

Rewards
No bull case signals
Risks
Risk below floor (2.4 < 3.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-5.8
Mkt Cap$471M
EV/EBITDA
Profit Mgn0.0%
ROE
Rev Growth
Beta
DividendNone
Rating analysts15

Quality Signals

Piotroski F4/9MoatNarrow

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

3 floor-breakers

Volatile — 7.4% daily ATR makes tight stops impractical. Position-size conservatively.static

Short Interest
0.0
Days To Cover
0.0
Volatility
0.0
Debt Equity
6.0
News Risk
6.0
High short interest: 28%

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Surprise Avg
0.0
Earnings History
1.1
Erm
5.0
News Activity
5.0
Earnings concerns: 1B/2M

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Obv
1.0
Volume
1.7
Macd
3.9
Ma Position
4.0
Rsi
7.6
Uptrend pullback (RSI 39) - buy opportunityVolume distribution (falling OBV)Above 200-day MA
GatesMomentum 3.6<4.5INSIDER 0.26%=MODERATEA.R:R 3.9 ≥ 1.5No SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY NO DATESEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Speculative
RSI
39 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $16.50Resistance $19.21

Price Targets

$16
$27
A.Upside+57.8%
A.R:R3.9:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Risk below floor (2.4 < 3.0)
! momentum at 3.6 (below the engine's 4.5 threshold)

Earnings

B
M
M
M
1/4 beats

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is CBIO stock a buy right now?

Sell if holding. Engine safety override at $17.09: Risk below floor (2.4 < 3.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.8/10 and A.R:R 3.9:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 28%; Below-average business quality; Negative price momentum. Chart setup: No clear chart pattern; technical signals are mixed. Prior stop was $16.00. Score 4.8/10, moderate confidence.

What is the CBIO stock price target?

Take-profit target: $26.97 (+57.8% upside). Prior stop was $16.00. Stop-loss: $16.00.

What are the risks of investing in CBIO?

Risk below floor (2.4 < 3.0).

Is CBIO overvalued or undervalued?

Crescent Biopharma, Inc. trades at a P/E of N/A (forward -5.8). TrendMatrix value score: 5.4/10. Verdict: Sell.

What do analysts say about CBIO?

15 analysts cover CBIO with a consensus score of 4.3/5. Average price target: $31.

What does Crescent Biopharma, Inc. do?Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United...

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. for the development and commercialization of oncology therapeutics. The company was formerly known as GlycoMimetics, Inc. The company was founded in 2024 and is headquartered in Waltham, Massachusetts.

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Latest News

Benzinga4d ago