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AURAAura Biosciences, Inc.Sell4.9·$7.05-2.08%
SellModerate Confidence
Investment thesis

Aura Biosciences offers high modeled upside and strong momentum ahead of binary clinical catalysts, but a quality score below the engine's floor, extreme insider selling, and sky-high implied volatility mark it as a highly speculative position.

Thesis pillars

  • Quality Below Engine FloorStable
  • Extreme Insider Selling Gate FailedStable
  • High Modeled UpsideImproving
  • +2 more pillars — see the Why tab for full reasoning

Full reasoning →

Open full analysis

Aura Biosciences, Inc. (AURA) Stock Analysis

Breakout setup · Inst Constrain edge

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $7.05: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 13.1:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality.

Aura Biosciences is a clinical-stage biotechnology company developing virus-like drug conjugates (VDCs) to treat solid tumors while preserving organ function. Its lead candidate, bel-sar, is in a global Phase 3 trial for early choroidal melanoma and in earlier-stage development... Read more

$7.05+132.0% A.UpsideScore 4.9/10#181 of 254 Biotechnology
QualityF-score4 / 9FCF yield-7.07%
Stop $6.56Target $16.36(analyst − 13%)A.R:R 13.1:1
Analyst target$18.80+166.7%5 analysts
$16.36our TP
$7.05price
$18.80mean
$24

Sell if holding. Engine safety override at $7.05: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 13.1:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality. Chart setup: Golden cross, above all MAs, RSI 49, MACD bullish. Score 4.9/10, moderate confidence.

Passes 5/8 gates (favorable risk/reward ratio, news events none recent, earnings proximity 19d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum and clean insider activity. Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-25

Recent Developments — Aura Biosciences, Inc.

Generated 2026-07-25T14:12:23Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 13, 202619d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Pipeline: bel-sar
Quality below floor (1.7 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-3.5
Mkt Cap$729M
EV/EBITDA-5.4
Profit Mgn0.0%
ROE-95.6%
Rev Growth
Beta0.40
DividendNone
Rating analysts12

Quality Signals

Piotroski F4/9

Options Flow

P/C1.00neutral

Concentration Risks(10-K Item 1A)

  • HIGHpipelinebel-sar
    10-K Item 1A: 'We are heavily dependent on the success of bel-sar, our only product candidate to date.'

Material Events(8-K, last 90d)

  • 2026-05-04Item 5.02MEDIUM
    Founder Dr. Elisabet de los Pinos departed as CEO, President, and director effective April 30, 2026. The Board appointed Natalie Holles, former CEO of Third Harmonic Bio, as successor CEO, President, and Class I director effective the same date. No reason for departure cited.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

3 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
4.4
Moat
4.8
Current Ratio
5.9
Cash-burning (FCF negative)No competitive moatQuality concerns

Insiders leaning net-seller recently. Could be diversification/taxes rather than view, but the signal is not supportive.static

Materiality
2.0
Insider Conviction
2.0
Heavy insider selling — $39,127,317 (5.366% of mkt cap)

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.1
Value Rank
5.0
Growth Rank
5.0
GatesMomentum 4.5<4.5INSIDER 5.37%=EXTREMEExecutive change: officer departure/appointmentA.R:R 13.1 ≥ 1.5NEWS EVENTS NONE RECENTEARNINGS PROXIMITY 19d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARBreakoutSuitability: Speculative
RSI
49 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $6.53Resistance $7.87

Price Targets

$7
$16
A.Upside+132.0%
A.R:R13.1:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.7 < 4.0)
! momentum at 4.5 (below the engine's 4.5 threshold)
! Insider activity: 5.37%=extreme

Earnings

B
B
M
M
2/4 beats
Next Earnings2026-08-13 (19d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AURA stock a buy right now?

Sell if holding. Engine safety override at $7.05: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.9/10 and A.R:R 13.1:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality. Chart setup: Golden cross, above all MAs, RSI 49, MACD bullish. Prior stop was $6.56. Score 4.9/10, moderate confidence.

What is the AURA stock price target?

Take-profit target: $16.36 (+132.0% upside). Prior stop was $6.56. Stop-loss: $6.56.

What are the risks of investing in AURA?

Concentration risk — Pipeline: bel-sar; Quality below floor (1.7 < 4.0).

Is AURA overvalued or undervalued?

Aura Biosciences, Inc. trades at a P/E of N/A (forward -3.5). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about AURA?

12 analysts cover AURA with a consensus score of 4.2/5. Average price target: $19.

What does Aura Biosciences, Inc. do?Aura Biosciences is a clinical-stage biotechnology company developing virus-like drug conjugates (VDCs) to treat solid...

Aura Biosciences is a clinical-stage biotechnology company developing virus-like drug conjugates (VDCs) to treat solid tumors while preserving organ function. Its lead candidate, bel-sar, is in a global Phase 3 trial for early choroidal melanoma and in earlier-stage development for metastases to the choroid, ocular-surface cancers, and non-muscle invasive bladder cancer. The company has no approved products or product revenue and reported a $106.2 million net loss in 2025 with an accumulated deficit of $480.4 million.

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