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ALNYAlnylam Pharmaceuticals, Inc.Sell6.7·$224.03
ALNY · Decision

Should you buy Alnylam Pharmaceuticals (ALNY)?

Updated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Editorial policy

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Methodology · Editorial policy & full disclaimer

Verdict
SELL
Score
6.7/10
Price
$224.03
Entry / Take Profit (TP) / Stop Loss (SL)
— / $331.83 / $209.00

Engine methodology range

$224.03
Bear
$159
Base
$227
Bull
$295

ALNY currently trades below the base anchor, in the lower half of the engine methodology range.

Engine methodology range — mechanically derived from pipeline gate outputs + peer-multiple inputs. Not an analyst price target. JSON-LD emission gated pending counsel review.

What the engine is tracking

  • Wide Moat Elite Growth Quality→Stable
  • Confirmed Downtrend Blocks Entry↓Deteriorating
  • Leverage Adds Downside Cushion Risk↑Improving
  • +1 more pillar — see the Why tab for full reasoning

→ Full pillar scorecard with all 4 pillars + per-dimension breakdown

When this thesis breaks

Falsifiable conditions per pillar — any one trip warrants review independent of price action. Engine-derived; not personalized advice.

Falsifying conditions — when triggered, the corresponding pillar's thesis is invalidated.

  • P1Wide Moat Elite Growth Quality

    Trip ifRevenue growth decelerates below 30% year-over-year for 2 consecutive quarters.

  • P2Confirmed Downtrend Blocks Entry

    Trip ifPrice closes above the 200-day moving average and on-balance volume turns positive for 20 or more consecutive sessions.

  • P3Leverage Adds Downside Cushion Risk

    Trip ifDebt-to-equity ratio falls below 1.5 within 4 consecutive quarters.

  • P4Earnings Large Consistent Surprises

    Trip ifEPS surprise falls below 0% in 2 of the next 3 reported quarters.

How the engine reached this verdict

1. Direct answer

TrendMatrix's engine output for Alnylam Pharmaceuticals, Inc. (ALNY) is SELL_IF_HOLDING with medium conviction, score 6.7/10 at $224.03. The C-path quality+growth combination cleared its gates — quality 8.2 and growth 10.0 — with 6.93 asymmetric R:R supporting the read.

2. Entry, target, and stop

The engine's exit framework anchors to a tactical sell band near $224.03, with structural invalidation at $209.00. The asymmetric R:R against a reversal hypothesis is 6.93 — the upside scenario exists, but it requires multiple structural gates to flip; the downside scenario requires only one more disappointment. The engine's sizing output: AVOID at this asymmetry level (no fresh-capital deployment).

3. What the engine sees

On the bull side: V7 flight-to-quality bonus: +0.5 (Q=8.2 in RISK_OFF); Sector modifier (Healthcare): +0.5; High-quality business. On the bear side: Leverage penalty (D/E 2.2): -1.5; Earnings in 6 days (event risk); Consecutive earnings misses (2). Active engine warnings: L3:NEWS_MOD=-2: STRONG_BUY_WAIT → SELL_IF_HOLDING, V9 Gate Failed: MOMENTUM:3.1<4.5, V9 Gate Failed: DEATH_CROSS:HARD_BLOCK.

4. What would change the verdict

The dominant failed gate is momentum at 3.1 vs threshold 4.5 (with co-failures: death cross, earnings proximity). SELL flips back toward HOLD if momentum recovers above its threshold AND a co-failing gate also clears. The strongest-cleared gate today is ASYMMETRY:6.9>=1.5.

For the full 10-dimension breakdown + V9 gate detail: Why TrendMatrix rates ALNY — 10-dimension breakdown →

Bull case

  • ▸V7 flight-to-quality bonus: +0.5 (Q=8.2 in RISK_OFF)
  • ▸Sector modifier (Healthcare): +0.5
  • ▸High-quality business

Bear case

  • ▸Leverage penalty (D/E 2.2): -1.5
  • ▸Earnings in 6 days (event risk)
  • ▸Consecutive earnings misses (2)
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