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RAREUltragenyx Pharmaceutical Inc.Sell5.3·$24.85-2.09%
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Ultragenyx Pharmaceutical Inc. (RARE) Stock Analysis

Recovery setup

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $24.85: Quality below floor (2.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10 and A.R:R 6.3:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Elevated put/call ratio: 2.80; Below-average business quality.

Ultragenyx is a late-stage biopharmaceutical company focused on rare genetic diseases, with four approved therapies (Crysvita for XLH/TIO, Mepsevii for MPS VII, Dojolvi for LC-FAOD, Evkeeza for HoFH) and multiple Phase 3 pipeline programs. Revenue comes from product sales and... Read more

$24.85+88.5% A.UpsideScore 5.3/10#79 of 157 Biotechnology
QualityF-score3 / 9FCF yield-8.76%
Stop $23.11Target $46.85(analyst − 10%)A.R:R 6.3:1
Analyst target$52.05+109.5%19 analysts
$46.85our TP
$24.85price
$52.05mean
$96

Sell if holding. Engine safety override at $24.85: Quality below floor (2.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10 and A.R:R 6.3:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Elevated put/call ratio: 2.80; Below-average business quality. Chart setup: Death cross but MACD improving, RSI 57. Score 5.3/10, moderate confidence.

Passes 8/9 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 49d clear, semi cycle peak clear, materials cycle peak clear). Suitability: aggressive.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-06-17

Recent Developments — Ultragenyx Pharmaceutical Inc.

Generated 2026-06-17T12:41:50Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Aug 4, 202649d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Quality below floor (2.4 < 4.0)
Value-trap signals (2/5): Revenue declining (-11.6% YoY), Margin compression (op margin 1.5%)

Key Metrics

P/E (TTM)
P/E (Fwd)26.3
Mkt Cap$2.5B
EV/EBITDA-6.6
Profit Mgn-90.9%
ROE
Rev Growth-2.2%
Beta0.38
DividendNone
Rating analysts25

Quality Signals

Piotroski F3/9

Options Flow

P/C2.80bearish
IV71%elevated
Max Pain$23-9.5% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

4 floor-breakers

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.9
52w Position
1.7
Support Resistance
1.9

Unprofitable operations — net margin -90.9%. Quality floor flags this regardless of sector context.static

Roa
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
3.3
Moat
3.8
Current Ratio
7.1
Cash-burning: FCF -33% of revenueNo competitive moatWeak Piotroski F-Score: 3/9Quality concerns

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/3M

Risk profile below the gate floor. Component breakdown shows what dragged the score down.static

Put Call
0.0
Volatility
0.6
Days To Cover
1.2
Implied Vol
1.5
Short Interest
2.0
Max Pain Risk
3.0
Beta
10.0
High short interest justified: 15%Elevated put/call: 2.80High IV: 71%Above max pain $22
GatesDeath cross (50MA < 200MA)Momentum 7.7>=5.5A.R:R 6.2 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 49d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRecoverySuitability: Aggressive
RSI
57 · Neutral
20D MA 50D MA 200D MADEATH CROSSSupport $21.33Resistance $25.66

Price Targets

$23
$47
A.Upside+88.5%
A.R:R6.3:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (2.4 < 4.0)
! Value-trap signals (2/5): Revenue declining (-11.6% YoY), Margin compression (op margin 1.5%)

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-04 (49d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is RARE stock a buy right now?

Sell if holding. Engine safety override at $24.85: Quality below floor (2.4 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10 and A.R:R 6.3:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Elevated put/call ratio: 2.80; Below-average business quality. Chart setup: Death cross but MACD improving, RSI 57. Prior stop was $23.11. Score 5.3/10, moderate confidence.

What is the RARE stock price target?

Take-profit target: $46.85 (+88.5% upside). Prior stop was $23.11. Stop-loss: $23.11.

What are the risks of investing in RARE?

Quality below floor (2.4 < 4.0); Value-trap signals (2/5): Revenue declining (-11.6% YoY), Margin compression (op margin 1.5%).

Is RARE overvalued or undervalued?

Ultragenyx Pharmaceutical Inc. trades at a P/E of N/A (forward 26.3). TrendMatrix value score: 7.9/10. Verdict: Sell.

What do analysts say about RARE?

25 analysts cover RARE with a consensus score of 4.2/5. Average price target: $52.

What does Ultragenyx Pharmaceutical Inc. do?Ultragenyx is a late-stage biopharmaceutical company focused on rare genetic diseases, with four approved therapies...

Ultragenyx is a late-stage biopharmaceutical company focused on rare genetic diseases, with four approved therapies (Crysvita for XLH/TIO, Mepsevii for MPS VII, Dojolvi for LC-FAOD, Evkeeza for HoFH) and multiple Phase 3 pipeline programs. Revenue comes from product sales and collaboration payments from Kyowa Kirin (KKC) and Gilead; as of December 31, 2025, available cash was $737M. The company is implementing a 10% workforce reduction (~130 employees) and ~$50M in restructuring charges in H1 2026 following UX143 Phase 3 failures.

Related stocks: INCY (Incyte Corporation) · AUPH (Aurinia Pharmaceuticals Inc) · HALO (Halozyme Therapeutics, Inc.) · ADMA (ADMA Biologics Inc) · KRYS (Krystal Biotech, Inc.)
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