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Intellia Therapeutics, Inc. (NTLA) Stock Analysis

Range Bound setup

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Biotechnology

Earnings in 7 days (2026-05-07). Expect elevated volatility around the report — consider waiting for post-earnings price action before new entries.

Sell if holding. Engine safety override at $13.64: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 5.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 37%; Elevated put/call ratio: 6.83; Below-average business quality.

Intellia Therapeutics is a clinical-stage biopharmaceutical company developing CRISPR gene editing therapies, with two lead programs in Phase 3: lonvo-z for hereditary angioedema and nex-z for ATTR amyloidosis. Revenue comes from collaborations, primarily with Regeneron. The... Read more

$13.64+77.0% A.UpsideScore 5.2/10#64 of 158 Biotechnology
Stop $12.70Target $24.17(analyst − 10%)A.R:R 5.1:1
Analyst target$26.86+96.9%21 analysts
$24.17our TP
$13.64price
$26.86mean
$106

Sell if holding. Engine safety override at $13.64: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 5.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 37%; Elevated put/call ratio: 6.83; Below-average business quality. Chart setup: RSI 51 mid-range, Bollinger mid-band. Score 5.2/10, moderate confidence.

Passes 5/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear). Fails on weak momentum and earnings proximity 7d<=7d. Suitability: aggressive.

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Pipeline: nex-z (NTLA-2001)
Concentration risk — Pipeline: lonvo-z (NTLA-2002)
Quality below floor (2.2 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-4.3
Mkt Cap$1.5B
EV/EBITDA-2.6
Profit Mgn0.0%
ROE-53.5%
Rev Growth78.8%
Beta1.99
DividendNone
Rating analysts30

Quality Signals

Piotroski F4/9

Options Flow

P/C6.83bearish
IV99%elevated
Max Pain$5-63.3% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHpipelinenex-z (NTLA-2001)
    10-K Item 1A: 'we cannot predict when we will resume the MAGNITUDE Phase 3 clinical trial for nex-z, and there is a risk that we may not be able to resume the trial at all'
  • HIGHpipelinelonvo-z (NTLA-2002)
    10-K Item 1A: 'clinical trials for nex-z (pending resolution of the clinical hold on the IND for the MAGNITUDE clinical trial) and for lonvo-z'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers·1 ceiling hit

Volatile — 9.6% daily ATR makes tight stops impractical. Position-size conservatively.static

Short Interest
0.0
Days To Cover
0.0
Volatility
0.0
Put Call
0.0
Implied Vol
0.0
Max Pain Risk
3.0
Beta
3.4
Debt Equity
9.4
High short interest justified: 37%Elevated put/call: 6.83High IV: 99%Above max pain $5Concentration risks: 2 HIGH (10-K Item 1A — sized via position_sizing, validated via buy_confidence)

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
4.4
Moat
5.0
Current Ratio
7.9
Cash-burning: FCF -345% of revenueNo competitive moatQuality concerns

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
1.8
Value Rank
2.3
Growth Rank
7.7

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Obv
1.0
Volume
3.9
Rsi
5.5
Ma Position
6.0
Volume distribution (falling OBV)Above 200-day MA
GatesMomentum 3.3<4.5EARNINGS PROXIMITY 7d<=7dA.R:R 5.1 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARRange BoundSuitability: Aggressive
RSI
51 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $11.76Resistance $16.97

Price Targets

$13
$24
A.Upside+77.2%
A.R:R5.1:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (2.2 < 4.0)
! Value-trap signals (2/5): Margin compression (op margin -3.4%), Material insider selling (104 sells, 0.27% of cap)
! Momentum score 3.3/10 — below 4.5 minimum

Earnings

B
B
B
B
4/4 beats
Next Earnings2026-05-07 (7d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is NTLA stock a buy right now?

Sell if holding. Engine safety override at $13.64: a dimension score below its floor triggers a hard block regardless of the otherwise-positive setup — overall score 5.2/10 and A.R:R 5.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 37%; Elevated put/call ratio: 6.83; Below-average business quality. Chart setup: RSI 51 mid-range, Bollinger mid-band. Prior stop was $12.70. Score 5.2/10, moderate confidence.

What is the NTLA stock price target?

Take-profit target: $24.17 (+77.0% upside). Prior stop was $12.70. Stop-loss: $12.70.

What are the risks of investing in NTLA?

Concentration risk — Pipeline: nex-z (NTLA-2001); Concentration risk — Pipeline: lonvo-z (NTLA-2002); Quality below floor (2.2 < 4.0).

Is NTLA overvalued or undervalued?

Intellia Therapeutics, Inc. trades at a P/E of N/A (forward -4.3). TrendMatrix value score: 5.4/10. Verdict: Sell.

What do analysts say about NTLA?

30 analysts cover NTLA with a consensus score of 3.7/5. Average price target: $27.

What does Intellia Therapeutics, Inc. do?Intellia Therapeutics is a clinical-stage biopharmaceutical company developing CRISPR gene editing therapies, with two...

Intellia Therapeutics is a clinical-stage biopharmaceutical company developing CRISPR gene editing therapies, with two lead programs in Phase 3: lonvo-z for hereditary angioedema and nex-z for ATTR amyloidosis. Revenue comes from collaborations, primarily with Regeneron. The company is preparing for a potential commercial launch of lonvo-z in the first half of 2027.

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