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Nurix Therapeutics, Inc. (NRIX) Stock Analysis

Range Bound setup

SellVALUE-TRAP 2/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $16.57: Quality below floor (1.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 6.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 19%; Elevated put/call ratio: 2.72; Below-average business quality.

Nurix Therapeutics is a clinical-stage biopharma using AI-integrated protein degradation technology to develop oncology and inflammatory disease treatments. Its three wholly owned clinical assets -- bexobrutideg (Phase 2 pivotal in CLL), zelebrudomide (Phase 1 in B-cell... Read more

$16.57+64.2% A.UpsideScore 4.2/10#144 of 158 Biotechnology
Stop $15.41Target $27.21(analyst − 10%)A.R:R 6.8:1
Analyst target$30.24+82.5%17 analysts
$27.21our TP
$16.57price
$30.24mean
$41

Sell if holding. Engine safety override at $16.57: Quality below floor (1.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 6.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 19%; Elevated put/call ratio: 2.72; Below-average business quality. Chart setup: RSI 55 mid-range, Bollinger mid-band. Score 4.2/10, moderate confidence.

Passes 6/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news boost analyst 0.75, earnings proximity 70d clear, semi cycle peak clear). Fails on weak momentum. Suitability: aggressive.

Thesis

Rewards
Recent Analyst detected in news
Risks
Concentration risk — Pipeline: bexobrutideg
Quality below floor (1.9 < 4.0)
Value-trap signals (2/5): Margin compression (op margin -3.4%), Material insider selling (104 sells, 0.27% of cap)

Key Metrics

P/E (TTM)
P/E (Fwd)-5.8
Mkt Cap$1.7B
EV/EBITDA-4.0
Profit Mgn0.0%
ROE-61.4%
Rev Growth-66.1%
Beta1.98
DividendNone
Rating analysts23

Quality Signals

Piotroski F3/9

Options Flow

P/C2.72bearish
IV101%elevated
Max Pain$8-51.7% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHpipelinebexobrutideg
    10-K Item 1A: 'Our lead drug candidates, bexobrutideg, zelebrudomide and NX-1607, are in the early stages of clinical development and their risk of failure is high.'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers·1 ceiling hit

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
1.1
Growth Rank
1.2
Value Rank
1.8

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
3.3
Moat
5.0
Current Ratio
7.0
Cash-burning: FCF -203% of revenueNo competitive moatWeak Piotroski F-Score: 3/9Quality concerns

Risk profile below the gate floor. Component breakdown shows what dragged the score down.static

Days To Cover
0.0
Put Call
0.0
Implied Vol
0.0
Volatility
1.1
Short Interest
1.6
Max Pain Risk
3.0
Beta
3.4
Debt Equity
9.5
High short interest justified: 19%Elevated put/call: 2.72High IV: 101%Above max pain $8Concentration risks: 1 HIGH (10-K Item 1A — sized via position_sizing, validated via buy_confidence)

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Volume
0.0
Obv
1.0
Macd
3.8
Rsi
5.5
Ma Position
9.0
Volume distribution (falling OBV)Above 200-day MA
GatesMomentum 3.9<4.5A.R:R 6.8 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS BOOST ANALYST 0.75EARNINGS PROXIMITY 70d clearSEMI CYCLE PEAK CLEARRange BoundSuitability: Aggressive
RSI
55 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $15.00Resistance $17.68

Price Targets

$15
$27
A.Upside+64.2%
A.R:R6.8:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.9 < 4.0)
! Value-trap signals (2/5): Margin compression (op margin -3.4%), Material insider selling (104 sells, 0.27% of cap)
! Momentum score 3.9/10 — below 4.5 minimum

Earnings

B
B
M
M
2/4 beats
Next Earnings2026-07-09 (70d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is NRIX stock a buy right now?

Sell if holding. Engine safety override at $16.57: Quality below floor (1.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.2/10 and A.R:R 6.8:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 19%; Elevated put/call ratio: 2.72; Below-average business quality. Chart setup: RSI 55 mid-range, Bollinger mid-band. Prior stop was $15.41. Score 4.2/10, moderate confidence.

What is the NRIX stock price target?

Take-profit target: $27.21 (+64.2% upside). Prior stop was $15.41. Stop-loss: $15.41.

What are the risks of investing in NRIX?

Concentration risk — Pipeline: bexobrutideg; Quality below floor (1.9 < 4.0); Value-trap signals (2/5): Margin compression (op margin -3.4%), Material insider selling (104 sells, 0.27% of cap).

Is NRIX overvalued or undervalued?

Nurix Therapeutics, Inc. trades at a P/E of N/A (forward -5.8). TrendMatrix value score: 5.4/10. Verdict: Sell.

What do analysts say about NRIX?

23 analysts cover NRIX with a consensus score of 4.3/5. Average price target: $30.

What does Nurix Therapeutics, Inc. do?Nurix Therapeutics is a clinical-stage biopharma using AI-integrated protein degradation technology to develop oncology...

Nurix Therapeutics is a clinical-stage biopharma using AI-integrated protein degradation technology to develop oncology and inflammatory disease treatments. Its three wholly owned clinical assets -- bexobrutideg (Phase 2 pivotal in CLL), zelebrudomide (Phase 1 in B-cell malignancies), and NX-1607 (Phase 1) -- are partnered with Gilead, Sanofi, and Pfizer for additional targets.

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