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Kymera Therapeutics, Inc. (KYMR) Stock Analysis

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $78.14: Quality below floor (1.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10 and A.R:R 3.6:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Below-average business quality; Negative price momentum.

Kymera Therapeutics is a clinical-stage biopharmaceutical company using targeted protein degradation (TPD) to develop oral medicines for immune-inflammatory diseases. Its lead programs target STAT6 (KT-621, Phase 2b in atopic dermatitis and asthma), IRF5 (KT-579, Phase 1), and... Read more

$78.14+36.2% A.UpsideScore 5.7/10#34 of 157 Biotechnology
QualityF-score3 / 9FCF yield-2.13%
Stop $74.56Target $106.45(analyst − 10%)A.R:R 3.6:1
Analyst target$118.27+51.4%22 analysts
$106.45our TP
$78.14price
$118.27mean
$140

Sell if holding. Engine safety override at $78.14: Quality below floor (1.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10 and A.R:R 3.6:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Below-average business quality; Negative price momentum. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Score 5.7/10, moderate confidence.

Passes 6/7 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity 83d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: aggressive.

Recent Developments — Kymera Therapeutics, Inc.

Generated 2026-05-20T20:21:21Z.

Thesis

Rewards
No bull case signals
Risks
Quality below floor (1.6 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-18.2
Mkt Cap$6.6B
EV/EBITDA-17.2
Profit Mgn0.0%
ROE-27.1%
Rev Growth55.5%
Beta2.06
DividendNone
Rating analysts29

Quality Signals

Piotroski F3/9

Options Flow

P/C0.38bullish
IV63%elevated

Material Events(8-K, last 90d)

  • 2026-02-26Item 1.01LOW
    Kymera entered at-the-market Sales Agreement with TD Cowen for up to $500M common stock offering. TD Cowen receives up to 3.0% commission. Company not obligated to sell; program active on Nasdaq.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers·2 ceiling hits

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
3.3
Moat
4.2
Current Ratio
5.0
Cash-burning: FCF -271% of revenueNo competitive moatWeak Piotroski F-Score: 3/9Quality concerns

Risk profile below the gate floor. Component breakdown shows what dragged the score down.static

Days To Cover
0.0
Volatility
0.0
Debt Equity
0.0
Short Interest
2.0
Implied Vol
2.8
Beta
3.1
Put Call
10.0
High short interest justified: 15%High IV: 63%

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Obv
1.0
Ma Position
4.0
Volume
4.3
Rsi
5.5
Volume distribution (falling OBV)Above 200-day MA

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
News Activity
5.0
Earnings concerns: 1B/3M
GatesMomentum 3.0<4.5A.R:R 3.6 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY 83d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Aggressive
RSI
43 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $76.87Resistance $90.10

Price Targets

$75
$106
A.Upside+36.2%
A.R:R3.6:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.6 < 4.0)
! Momentum score 3.0/10 — below 4.5 minimum

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-10 (83d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is KYMR stock a buy right now?

Sell if holding. Engine safety override at $78.14: Quality below floor (1.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.7/10 and A.R:R 3.6:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 15%; Below-average business quality; Negative price momentum. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Prior stop was $74.56. Score 5.7/10, moderate confidence.

What is the KYMR stock price target?

Take-profit target: $106.45 (+36.2% upside). Prior stop was $74.56. Stop-loss: $74.56.

What are the risks of investing in KYMR?

Quality below floor (1.6 < 4.0).

Is KYMR overvalued or undervalued?

Kymera Therapeutics, Inc. trades at a P/E of N/A (forward -18.2). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about KYMR?

29 analysts cover KYMR with a consensus score of 4.3/5. Average price target: $118.

What does Kymera Therapeutics, Inc. do?Kymera Therapeutics is a clinical-stage biopharmaceutical company using targeted protein degradation (TPD) to develop...

Kymera Therapeutics is a clinical-stage biopharmaceutical company using targeted protein degradation (TPD) to develop oral medicines for immune-inflammatory diseases. Its lead programs target STAT6 (KT-621, Phase 2b in atopic dermatitis and asthma), IRF5 (KT-579, Phase 1), and IRAK4 (KT-485 via Sanofi collaboration). The company has no product revenue and had $1.6B cash as of Dec 31, 2025.

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