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GKOSGlaukos CorporationHold5.4·$179.87-1.12%
HoldModerate Confidence
Investment thesis

Glaukos is growing revenue at 41% annually, leads its peer group in growth, and carries positive price momentum with a golden cross technical setup, while analyst sentiment is constructively bullish and news flow is favorable. However, the stock is trading roughly 12% above the entry price where the risk/reward is mathematically attractive—at the current price only 4.5% separates the stock from the analyst target while potential downside is materially wider—and four high-severity revenue concentration risks alongside an expensive valuation (PEG 2.59) argue for waiting rather than chasing.

Thesis pillars

  • Industry Leading Revenue GrowthStable
  • Rich Valuation Limited Margin Of ErrorStable
  • Four High Severity Concentration RisksDeteriorating
  • +2 more pillars — see the Why tab for full reasoning

Full reasoning →

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Glaukos Corporation (GKOS) Stock Analysis

Range Bound setup

HoldVALUE-TRAP 2/5GrowthModerate Confidence

Healthcare · Medical Devices

Hold if already holding. Not a fresh buy at $179.87, but acceptable to hold if already in. Reasons: Concentration risk — Geographic: U.S. customers (74.0%); Concentration risk — Product: iStent family and iDose TR glaucoma franchise (83.0%).

Glaukos develops and sells ophthalmic devices and pharmaceuticals for glaucoma, corneal disorders, and retinal disease, with 74% of 2025 net sales from U.S. customers. The glaucoma franchise — iStent devices and iDose TR — accounted for approximately 83% of net sales; iLink... Read more

$179.87-4.6% A.UpsideScore 5.4/10#33 of 61 Medical Devices
QualityF-score6 / 9FCF yield0.14%
Stop $167.63Target $187.79(resistance)A.R:R -0.7:1
Analyst target$197.15+9.6%13 analysts
$187.79our TP
$179.87price
$197.15mean
$172
$225

Hold if already holding. Not a fresh buy at $179.87, but acceptable to hold if already in. Reasons: Concentration risk — Geographic: U.S. customers (74.0%); Concentration risk — Product: iStent family and iDose TR glaucoma franchise (83.0%). Chart setup: RSI 48 mid-range, Bollinger mid-band. Multiple concerning factors. Consider reducing position. | News modifier +2 (SELL_IF_HOLDING → HOLD_IF_HOLDING) Score 5.4/10, moderate confidence.

Passes 6/8 gates (clean insider activity, no SEC red flags, news events none recent, earnings proximity 61d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum and favorable risk/reward ratio. Suitability: moderate.

10-K grounded · weekly refresh

About Glaukos Corporation

About Glaukos Corporation

Glaukos' glaucoma franchise — the iStent family (first FDA-cleared in 2012) and the iDose TR intracameral travoprost implant (FDA-approved December 2023) — accounted for approximately 83% of 2025 net sales, with the iLink corneal cross-linking platform contributing approximately 17%. U.S. customers represented 74% of net sales in 2025 and international customers 26%, with no single customer exceeding 10% of total net sales. Epioxa, an epi-on corneal cross-linking therapy, received FDA approval in October 2025 with commercial launch planned for early 2026.

Glaukos generates revenue through a U.S. direct sales force targeting ambulatory surgery centers, hospitals, and private practices, and through direct subsidiaries and distribution partners in Australia, Brazil, Canada, Germany, Japan, and the United Kingdom. The iStent family and iDose TR are reimbursed by Medicare and major private payers; physician fee reimbursement for iDose TR continues to be standardized across Medicare Administrative Contractors via temporary CPT codes. Manufacturing for the iStent and iDose product lines is concentrated at a sole campus in San Clemente, California, and the company relies on sole-source third-party suppliers for certain device and drug components. Glaukos competes in glaucoma primarily against Alcon, AbbVie, Sight Sciences, and Iantrek, and holds the only FDA-approved bio-activated pharmaceutical for keratoconus.

Show full overview

Local coverage determinations finalized by five of seven Medicare Administrative Contractors in November 2024 confirmed non-coverage for surgical MIGS procedures performed in combination with other surgical MIGS procedures, disrupting traditional ordering patterns and potentially weighing on U.S. glaucoma revenue through 2025 and beyond. The iDose platform's longer-term trajectory depends on Phase 2b/3 trial outcomes for the second-generation iDose TREX and the Phase 3 iDose TRIO program; if those trials fail to support expanded indications, the franchise may remain confined to the first-generation travoprost implant in open-angle glaucoma and ocular hypertension.

See also: Healthcare · Medical Devices

From Glaukos Corporation's most recent 10-K filing, extracted June 10, 2026.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-08-29

Recent Developments — Glaukos Corporation

Generated 2026-08-29T09:07:27Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Wed, Oct 28, 202661d to earnings· next earnings call

Thesis

Rewards
Strong earnings beat streak (3/4)
Positive news sentiment (+0.67)
Strong growth profile
Risks
Concentration risk — Geographic: U.S. customers (74.0%)
Concentration risk — Product: iStent family and iDose TR glaucoma franchise (83.0%)
Analyst target reached - limited upside remaining

Key Metrics

P/E (TTM)
P/E (Fwd)360.7
Mkt Cap$10.7B
EV/EBITDA-284.8
Profit Mgn-30.7%
ROE-26.0%
Rev Growth49.5%
Beta0.76
DividendNone
Rating analysts21

Quality Signals

Piotroski F6/9MoatNarrow

Options Flow

P/C1.18bearish
IV48%normal

Concentration Risks(10-K Item 1A)

  • HIGHGeographicU.S. customers74%
    10-K Item 1: 'sales to U.S. and international customers accounted for 74% and 26% of our net sales, respectively'
  • HIGHProductiStent family and iDose TR glaucoma franchise83%
    10-K Item 1: 'our iStent family of products, iDose TR, and related glaucoma accessories accounted for approximately 83% of our net sales'
  • HIGHSuppliersole manufacturing campus in San Clemente
    10-K Item 1A: 'Our sole manufacturing location for our iStent and iDose products is an approximately 120,000 square foot campus located in San Clemente, California'
  • HIGHSuppliersole third-party component suppliers
    10-K Item 1A: 'we rely on a limited number of third-party suppliers, in some cases sole suppliers, to supply components for the iStent, the iStent inject models, the iStent infinite, the iDose TR'

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Not investment advice. TrendMatrix is not a registered investment adviser. Our content is for informational and educational purposes only. Consult your own licensed investment adviser, broker, or tax professional before making any investment decision.

Conflicts and positions. The TrendMatrix editorial team frequently holds personal long-term positions in securities discussed. We disclose positions held at the time of publication on each piece. We maintain a trading-window policy: we do not initiate or close positions in the same direction as a TrendMatrix publication within 24 hours before or 72 hours after publication.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

2 floor-breakers·1 ceiling hit

Priced at a premium — multiples above sector norms. Needs delivery on growth + margins to justify.static

Ps
0.0
Peg Ratio
3.6
Analyst Target
4.0
PEG: 3.13Expensive valuation

Momentum below the gate floor. Component breakdown shows what dragged the score down.static

Macd
0.0
Obv
1.0
Volume
2.1
Rsi
5.5
Ma Position
6.0
Volume distribution (falling OBV)Above 200-day MA
GatesMomentum 2.9<4.5A.R:R -0.7=NEGATIVEInsider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 61d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Moderate
RSI
48 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $167.64Resistance $191.62

Price Targets

$168
$188
A.Upside-4.6%
A.R:R-0.7:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Target reached (-4.6% upside)
! News modifier +2: SELL_IF_HOLDING → HOLD_IF_HOLDING
! momentum at 2.9 (below the engine's 4.5 threshold)

Earnings

B
B
B
M
3/4 beats
Next Earnings2026-10-28 (61d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is GKOS stock a buy right now?

Hold if already holding. Not a fresh buy at $179.87, but acceptable to hold if already in. Reasons: Concentration risk — Geographic: U.S. customers (74.0%); Concentration risk — Product: iStent family and iDose TR glaucoma franchise (83.0%). Chart setup: RSI 48 mid-range, Bollinger mid-band. Multiple concerning factors. Consider reducing position. | News modifier +2 (SELL_IF_HOLDING → HOLD_IF_HOLDING) Target $187.79 (+4.4%), stop $167.63 (−7.3%), A.R:R -0.7:1. Score 5.4/10, moderate confidence.

What is the GKOS stock price target?

Take-profit target: $187.79 (-4.6% upside). Target $187.79 (+4.4%), stop $167.63 (−7.3%), A.R:R -0.7:1. Stop-loss: $167.63.

What are the risks of investing in GKOS?

Concentration risk — Geographic: U.S. customers (74.0%); Concentration risk — Product: iStent family and iDose TR glaucoma franchise (83.0%); Analyst target reached - limited upside remaining.

Is GKOS overvalued or undervalued?

Glaukos Corporation trades at a P/E of N/A (forward 360.7). TrendMatrix value score: 2.3/10. Verdict: Hold.

What do analysts say about GKOS?

21 analysts cover GKOS with a consensus score of 4.2/5. Average price target: $197.

What does Glaukos Corporation do?Glaukos develops and sells ophthalmic devices and pharmaceuticals for glaucoma, corneal disorders, and retinal disease,...

Glaukos develops and sells ophthalmic devices and pharmaceuticals for glaucoma, corneal disorders, and retinal disease, with 74% of 2025 net sales from U.S. customers. The glaucoma franchise — iStent devices and iDose TR — accounted for approximately 83% of net sales; iLink corneal cross-linking therapies contributed approximately 17%. iDose TR was FDA-approved in December 2023; Epioxa, approved in October 2025, is planned for commercial launch in early 2026.

Related stocks: GMED (Globus Medical, Inc.) · PODD (Insulet Corporation) · LIVN (LivaNova PLC) · ATEC (Alphatec Holdings, Inc.) · DXCM (DexCom, Inc.)
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