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BioNTech SE (BNTX) Stock Analysis

Falling Knife setup

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $88.97: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.1/10 and A.R:R 3.3:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum; Below long-term trend.

BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial,... Read more

$88.97+27.2% A.UpsideScore 4.1/10#146 of 157 Biotechnology
QualityF-score4 / 9FCF yield-1.91%
Stop $85.18Target $113.06(analyst − 10%)A.R:R 3.3:1
Analyst target$125.63+41.2%17 analysts
$113.06our TP
$88.97price
$125.63mean
$76
$157

Sell if holding. Engine safety override at $88.97: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.1/10 and A.R:R 3.3:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum; Below long-term trend. Chart setup: Death cross, below all MAs, RSI 22, MACD bearish. Score 4.1/10, moderate confidence.

Passes 7/9 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 77d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum and death cross (50MA < 200MA). Suitability: aggressive.

Recent Developments — BioNTech SE

Generated 2026-05-20T20:21:21Z.

Thesis

Rewards
No bull case signals
Risks
Quality below floor (2.9 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-16.4
Mkt Cap$22.5B
EV/EBITDA-7.6
Profit Mgn-44.6%
ROE-6.7%
Rev Growth-35.4%
Beta1.37
DividendNone
Rating analysts26

Quality Signals

Piotroski F4/9

Options Flow

P/C0.41bullish
IV52%elevated
Max Pain$75-15.7% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers

Revenue shrinking — -35.4% YoY. Growth thesis broken unless recovery story develops.static

Revenue Growth
0.0
Declining revenue: -35%
Low model confidence on this dimension (33%).

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Macd
0.0
Obv
1.0
Ma Position
1.0
Rsi
3.0
Volume
3.5
Capitulation risk (RSI 22, below 200MA)Volume distribution (falling OBV)Below 200-MA, MA slope -1.7%/30d — confirmed downtrend

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 0B/4M

Unprofitable operations — net margin -44.6%. Quality floor flags this regardless of sector context.static

Roe
0.0
Roa
0.0
Net Margin
0.0
Fcf Quality
0.0
Rule Of 40
3.0
Moat
4.0
Piotroski F
4.4
Current Ratio
5.0
Gross Margin
10.0
Cash-burning: FCF -15% of revenueNo competitive moatRule of 40: -51 (fail)Quality concerns
GatesMomentum 1.7<4.5Death cross (50MA < 200MA)A.R:R 3.3 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 77d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARFalling KnifeSuitability: Aggressive
RSI
22 · Oversold
20D MA 50D MA 200D MADEATH CROSSSupport $87.81Resistance $113.26

Price Targets

$85
$113
A.Upside+27.1%
A.R:R3.3:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (2.9 < 4.0)
! Momentum score 1.7/10 — below 4.5 minimum
! Death cross — 50-day MA below 200-day MA

Earnings

M
M
M
M
0/4 beats
Next Earnings2026-08-04 (77d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is BNTX stock a buy right now?

Sell if holding. Engine safety override at $88.97: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.1/10 and A.R:R 3.3:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum; Below long-term trend. Chart setup: Death cross, below all MAs, RSI 22, MACD bearish. Prior stop was $85.18. Score 4.1/10, moderate confidence.

What is the BNTX stock price target?

Take-profit target: $113.06 (+27.2% upside). Prior stop was $85.18. Stop-loss: $85.18.

What are the risks of investing in BNTX?

Quality below floor (2.9 < 4.0).

Is BNTX overvalued or undervalued?

BioNTech SE trades at a P/E of N/A (forward -16.4). TrendMatrix value score: 7.3/10. Verdict: Sell.

What do analysts say about BNTX?

26 analysts cover BNTX with a consensus score of 4.0/5. Average price target: $126.

What does BioNTech SE do?BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in...

BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer. In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma. Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox. The company was incorporated in 2008 and is headquartered in Mainz, Germany.

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