BlossomHill is a pre-revenue, loss-making biotech whose case rests on heavy insider buying and a 128% gap to the analyst target, offset by weak quality, falling momentum and a near-term earnings event.
Thesis pillars
- Large Analyst Target Upside↓Deteriorating
- Weak Quality And Losses→Stable
- Heavy Insider Buying Conviction↓Deteriorating
- +2 more pillars — see the Why tab for full reasoning
Pillars as of Nov 8, 2026
BlossomHill Therapeutics, Inc. (BLSM) Stock Analysis
Range Bound setup · Inst Constrain edge
Healthcare · Biotechnology
Sell if holding. Engine safety override at $13.50: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10 and A.R:R 8.5:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum.
BlossomHill Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecule medicines that address medical needs in cancer treatment. Its pipeline includes BH-30643, an OMNI-EGFR inhibitor in clinical development for advanced EGFR-mutant non-small cell... Read more
Sell if holding. Engine safety override at $13.50: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10 and A.R:R 8.5:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum. Chart setup: RSI 47 mid-range, Bollinger mid-band. Score 5.3/10, moderate confidence.
Passes 6/8 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum and earnings proximity 7d<=7d. Suitability: speculative.
Recent developments
updated Nov 4, 2026Recent Developments — BlossomHill Therapeutics, Inc.
Latest news
- NEWS BlossomHill Therapeutics Announces Upcoming Poster Presentation for BH-30236 at ASH Annual Meeting — fiscal.ai Nov 4, 2026
- NEWS BlossomHill Therapeutics to Participate in Guggenheim's 3rd Annual Healthcare Innovations Conference — fiscal.ai Nov 3, 2026
- NEWS BlossomHill Therapeutics Announces Collaboration with Foundation Medicine to Develop First Companion Diagnostic for BH-3 — fiscal.ai Oct 22, 2026 positive
- NEWS BlossomHill Therapeutics Collaborates With Foundation Medicine To Develop Companion Diagnostic Assay For EGFR C797S Resi — benzinga Oct 22, 2026 positive
- NEWS BlossomHill Therapeutics Presents Preclinical Data On BH-501284 At AACR Conference On Pancreatic Cancer; Targets IND Fil — benzinga Sep 28, 2026 positive
Latest item Nov 4, 2026 · Generated 2026-11-09T11:52:55Z.
Upcoming dated catalysts
Thesis
Key Metrics
Quality Signals
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Editorial policy
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Rating Breakdown
3 floor-breakers·1 ceiling hit
No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static
Quality below the gate floor. Component breakdown shows what dragged the score down.static
Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static
Price Targets
Position Sizing
Risk Alerts
Earnings
Verdict History
Frequently Asked Questions
Sell if holding. Engine safety override at $13.50: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10 and A.R:R 8.5:1 is above the 1.5:1 BUY gate. Specifically: Below-average business quality; Negative price momentum. Chart setup: RSI 47 mid-range, Bollinger mid-band. Prior stop was $12.56. Score 5.3/10, moderate confidence.
Analyst target: $30.80 (+128.1% upside). Prior stop was $12.56. Stop-loss: $12.56.
Quality below floor (2.9 < 4.0); Value-trap signals (2/5): Margin compression (op margin -39.6%), Material insider selling (19 sells, 0.99% of cap).
BlossomHill Therapeutics, Inc. trades at a P/E of N/A (forward -3.4). TrendMatrix value score: 9.0/10. Verdict: Sell.
11 analysts rate BLSM, with a consensus score of 4.3/5. 5 analysts publish price targets averaging $35.
What does BlossomHill Therapeutics, Inc. do?BlossomHill Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecule medicines that...
BlossomHill Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecule medicines that address medical needs in cancer treatment. Its pipeline includes BH-30643, an OMNI-EGFR inhibitor in clinical development for advanced EGFR-mutant non-small cell lung cancer (NSCLC), BH-501284, and BH-30236, a macrocyclic CLK (Cdc2-like kinase) inhibitor being evaluated in patients with relapsed or refractory acute myeloid leukemia (R/R AML) and higher-risk myelodysplastic syndrome (HR-MDS). BlossomHill Therapeutics, Inc. was incorporated in 2020 and is based in San Diego, California.