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AUTLAutolus Therapeutics plcHold5.8·$1.38
HoldModerate Confidence
Investment thesis

Autolus is growing revenue 118% YoY from a small base but burns cash at -171% of revenue, trades in a downtrend near $1.54, and has no usable analyst target after the raw figure was rejected as implausible.

Thesis pillars

  • Cash Burn Funding Risk→Stable
  • Rapid Revenue Growth→Stable
  • Downtrend Pullback↓Deteriorating
  • +2 more pillars — see the Why tab for full reasoning

Pillars as of Oct 24, 2026, based on the 10-K filed Mar 27, 2026

Full reasoning →

Open full analysis

Autolus Therapeutics plc (AUTL) Stock Analysis

Oversold Bounce setup · Inst Constrain edge

HoldVALUE-TRAP 1/5GrowthModerate Confidence

Healthcare · Biotechnology

Earnings in 5 days (2026-11-10). Expect elevated volatility around the report — consider waiting for post-earnings price action before new entries.

Hold if already holding. Not a fresh buy at $1.38, but acceptable to hold if already in. Reasons: DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.38 — ratio 6.3×). Rejected, falling back to technical TP.; Market cap $367M below $400M minimum.

Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory B-cell precursor acute lymphoblastic leukemia, approved by the FDA in November 2024 and launched in the U.S. in January 2025, with the UK's MHRA and the European... Read more

$1.38+29.0% Upside to targetScore 5.8/10#63 of 241 Biotechnology
QualityF-score3 / 9FCF yield-54.77%
Stop $1.29Resistance target $1.78A.R:R 0.0:1
Analyst consensus$8.75+534.1%8 analysts with price targets
$1.78Resistance target
$1.38price
$8.75mean
$11

Hold if already holding. Not a fresh buy at $1.38, but acceptable to hold if already in. Reasons: DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.38 — ratio 6.3×). Rejected, falling back to technical TP.; Market cap $367M below $400M minimum. Chart setup: Oversold RSI 25, near Bollinger lower, volume surge. Market cap $367M below $400M minimum. Not in investable universe. Score 5.8/10, moderate confidence.

Passes 5/8 gates (clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum and earnings proximity 5d<=7d. Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated Nov 4, 2026
TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Nov 10, 20265d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.38 — ratio 6.3×). Rejected, falling back to technical TP.
Market cap $367M below $400M minimum

Key Metrics

P/E (TTM)—
P/E (Fwd)-2.2
Mkt Cap$367M
EV/EBITDA-2.3
Profit Mgn-238.7%
ROE-133.0%
Rev Growth118.4%
Beta2.35
DividendNone
Analysts with ratings16

Quality Signals

Piotroski F3/9

Options Flow

P/C5.00bearish

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Editorial policy

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About TrendMatrix. TrendMatrix is a publisher of general securities research and market commentary. We publish on a regular schedule. All content is the same for every subscriber in a tier — we do not provide personalized investment advice and we do not take into account any individual subscriber's financial situation, investment objectives, risk tolerance, tax situation, or holdings.

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Conflicts and positions. People who build TrendMatrix, or entities they control, may hold positions, long or short, in securities it covers, and may trade them at any time. Positions are not disclosed individually. Verdicts are generated by an automated model applied by the same rules to every covered stock, and are not adjusted for any position held by the people who build TrendMatrix. We do not accept payment from issuers for coverage.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

4 floor-breakers·2 ceiling hits

Clinical-stage biotech: losses expected pre-commercialisation. Quality floor doesn't distinguish R&D investment from operational decay — components above tell the real story.static

Roe
0.0
Roa
0.0
Operating Margin
0.0
Fcf Quality
0.0
Piotroski F
3.3
Moat
4.2
Current Ratio
8.1
Cash-burning: FCF -171% of revenueNo competitive moatWeak Piotroski F-Score: 3/9Quality concerns

Volatile — 7.1% daily ATR makes tight stops impractical. Position-size conservatively.static

Volatility
0.0
Put Call
0.0
Debt Equity
0.1
Beta
2.2
Max Pain Risk
3.0
Days To Cover
4.9
Short Interest
7.4
Elevated put/call: 5.00Above max pain $0

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Obv
1.0
Ma Position
2.2
Rsi
3.0
Macd
3.8
Volume
5.6
Capitulation risk (RSI 25, below 200MA)Volume distribution (falling OBV)Below 200-MA but MA still rising (+0.2%/30d) — pullback in uptrend, not confirmed weakness

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
News Activity
8.0
Earnings concerns: 0B/3MEarnings in 5 days
GatesMomentum 3.1<4.5EARNINGS PROXIMITY 5d<=7dA.R:R UPSIDE_EXHAUSTED (upside=0.0%)Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEAROversold BounceSuitability: Speculative
RSI
25 · Oversold
↓ 20D MA↓ 50D MA↓ 200D MAGOLDEN CROSSSupport $1.33Resistance $1.82

Price Targets

$1
$2
A.R:R0.0:1

Position Sizing

ConvictionNone
Suggested %0%
Max %0%
RegimeSteady

Risk Alerts

! DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.38 — ratio 6.3×). Rejected, falling back to technical TP.
! Market cap $367M below $400M minimum
! momentum at 3.1 (below the engine's 4.5 threshold)

Earnings

M
M
M
M
0/4 beats
Next Earnings2026-11-10 (5d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AUTL stock a buy right now?

Hold if already holding. Not a fresh buy at $1.38, but acceptable to hold if already in. Reasons: DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.38 — ratio 6.3×). Rejected, falling back to technical TP.; Market cap $367M below $400M minimum. Chart setup: Oversold RSI 25, near Bollinger lower, volume surge. Market cap $367M below $400M minimum. Not in investable universe. Resistance target $1.78 (+29.0%), stop $1.29 (−7.0%), A.R:R 0.0:1. Score 5.8/10, moderate confidence.

What is the AUTL stock price target?

Resistance target: $1.78 (+29.0% upside). Resistance target $1.78 (+29.0%), stop $1.29 (−7.0%), A.R:R 0.0:1. Stop-loss: $1.29.

What are the risks of investing in AUTL?

DATA_ISSUE: analyst_target_implausible (raw $8.75 vs price $1.38 — ratio 6.3×). Rejected, falling back to technical TP.; Market cap $367M below $400M minimum.

Is AUTL overvalued or undervalued?

Autolus Therapeutics plc trades at a P/E of N/A (forward -2.2). TrendMatrix value score: 8.2/10. Verdict: Hold.

What do analysts say about AUTL?

16 analysts rate AUTL, with a consensus score of 4.3/5. 8 analysts publish price targets averaging $9.

What does Autolus Therapeutics plc do?Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory...

Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory B-cell precursor acute lymphoblastic leukemia, approved by the FDA in November 2024 and launched in the U.S. in January 2025, with the UK's MHRA and the European Commission granting conditional and full marketing authorizations since. The company posted a $287.5 million net loss in 2025 against a $1,386.8 million accumulated deficit, and expects AUCATZYL to generate substantially all of its product revenue for the foreseeable future.

Related stocks: HRMY (Harmony Biosciences Holdings, I) · ZVRA (Zevra Therapeutics, Inc.) · CRMD (CorMedix Inc.) · PHAT (Phathom Pharmaceuticals, Inc.) · INVA (Innoviva, Inc.)
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