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AUTLAutolus Therapeutics plcSell5.3·$1.50-1.32%
SellModerate Confidence
Investment thesis

Autolus is a small, cell-therapy biotech with quality metrics below the engine's floor and a rejected analyst target, leaving flat momentum near 52-week lows and a recent earnings-miss pattern as the dominant near-term signals.

Thesis pillars

  • Quality Below Engine FloorStable
  • Rejected Implausible Analyst TargetStable
  • Flat Momentum Near LowsImproving
  • +2 more pillars — see the Why tab for full reasoning

Full reasoning →

Open full analysis

Autolus Therapeutics plc (AUTL) Stock Analysis

Range Bound setup · Inst Constrain edge

SellValueModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $1.50: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10. Specifically: Below-average business quality; Below long-term trend.

Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory B-cell precursor acute lymphoblastic leukemia, approved by the FDA in November 2024 and launched in the U.S. in January 2025, with the UK's MHRA and the European... Read more

$1.50+14.0% A.UpsideScore 5.3/10#112 of 254 Biotechnology
QualityF-score3 / 9FCF yield
Stop $1.40Target $1.71(resistance)A.R:R 0.0:1
Analyst target$8.55+470.0%8 analysts
$1.71our TP
$1.50price
$8.55mean
$11

Sell if holding. Engine safety override at $1.50: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10. Specifically: Below-average business quality; Below long-term trend. Chart setup: RSI 41 mid-range, Bollinger mid-band. Score 5.3/10, moderate confidence.

Passes 5/8 gates (clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: speculative.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Fri, Aug 7, 202613d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
DATA_ISSUE: analyst_target_implausible (raw $8.55 vs price $1.50 — ratio 5.7×). Rejected, falling back to technical TP.
Quality below floor (1.7 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-2.5
Mkt Cap$405M
EV/EBITDA2.3
Profit Mgn0.0%
ROE-29.6%
Rev Growth
Beta
DividendNone
Rating analysts16

Quality Signals

Piotroski F3/9

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

3 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Net Margin
0.0
Piotroski F
3.3
Moat
3.8
Current Ratio
5.0
No competitive moatWeak Piotroski F-Score: 3/9Quality concerns

Volatile — 6.7% daily ATR makes tight stops impractical. Position-size conservatively.static

Days To Cover
0.0
Volatility
0.0
Short Interest
6.4

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/3MEarnings in 13 days
GatesMomentum 4.1<4.5A.R:R UPSIDE_EXHAUSTED (upside=0.0%)EARNINGS PROXIMITY 13d<=14d (soft)Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Speculative
RSI
41 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $1.38Resistance $1.75

Price Targets

$1
$2
A.R:R0.0:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! DATA_ISSUE: analyst_target_implausible (raw $8.55 vs price $1.50 — ratio 5.7×). Rejected, falling back to technical TP.
! Quality below floor (1.7 < 4.0)
! momentum at 4.1 (below the engine's 4.5 threshold)

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-07 (13d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AUTL stock a buy right now?

Sell if holding. Engine safety override at $1.50: Quality below floor (1.7 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.3/10. Specifically: Below-average business quality; Below long-term trend. Chart setup: RSI 41 mid-range, Bollinger mid-band. Prior stop was $1.40. Score 5.3/10, moderate confidence.

What is the AUTL stock price target?

Take-profit target: $1.71 (+14.0% upside). Prior stop was $1.40. Stop-loss: $1.40.

What are the risks of investing in AUTL?

DATA_ISSUE: analyst_target_implausible (raw $8.55 vs price $1.50 — ratio 5.7×). Rejected, falling back to technical TP.; Quality below floor (1.7 < 4.0).

Is AUTL overvalued or undervalued?

Autolus Therapeutics plc trades at a P/E of N/A (forward -2.5). TrendMatrix value score: 10.0/10. Verdict: Sell.

What do analysts say about AUTL?

16 analysts cover AUTL with a consensus score of 4.3/5. Average price target: $9.

What does Autolus Therapeutics plc do?Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory...

Autolus Therapeutics markets AUCATZYL (obe-cel), a CD19-targeted CAR T cell therapy for adult relapsed or refractory B-cell precursor acute lymphoblastic leukemia, approved by the FDA in November 2024 and launched in the U.S. in January 2025, with the UK's MHRA and the European Commission granting conditional and full marketing authorizations since. The company posted a $287.5 million net loss in 2025 against a $1,386.8 million accumulated deficit, and expects AUCATZYL to generate substantially all of its product revenue for the foreseeable future.

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