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ZVRAZevra Therapeutics, Inc.Buy Wait7.3·$9.53-23.88%
ZVRA · Concentration risk · 10-K extracted

Zevra Therapeutics (ZVRA) concentration risks

Updated

The most significant concentration Zevra Therapeutics discloses is MIPLYFFA at 82%, classified HIGH by disclosed size. Below: the full set from the latest 10-K — verbatim quotes, filing references, and a synthesis of what these exposures mean together.

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Source: Zevra Therapeutics’s SEC Form 10-K filed view the filing on SEC EDGAR ↗

At a glance

Disclosed-size breakdown · 1 disclosed concentration

HIGH1
MEDIUM0
LOW0
Disclosed concentrations

Each card carries a disclosed-size chip (HIGH / MEDIUM / LOW — how large the exposure is as a share of revenue, not how dangerous it is) and a nature tag: Built-in(the company’s own model, geography, or products) or Outside party (an external customer, supplier, or distributor it relies on).

HIGHBuilt-in & outside partyProduct / Revenue mix
82%

MIPLYFFA

10-K Item 1A: 'For the year ended December 31, 2025 we derived approximately 82% of our revenues from commercial sales of MIPLYFFA'
SEC 10-K · filed Mar 2026
TrendMatrix Research · concentration synthesis

What these concentrations mean together

updated 2026-07-06

Zevra Therapeutics' revenue is heavily concentrated in a single commercial product: approximately 82% of 2025 revenues were derived from commercial sales of MIPLYFFA, a high-share exposure with a mixed character, combining the structural fact of a single-product commercial base with the dependency-like sensitivity of that revenue to ongoing demand, pricing, and reimbursement dynamics for one drug. Because MIPLYFFA accounts for such a large share of the top line, any disruption to its commercial trajectory — whether from competitive entry, reimbursement changes, or manufacturing issues — would flow through to reported revenue with little offsetting diversification from other products. This single exposure is therefore the primary variable most capable of moving the verdict on Zevra, since there is no comparably sized second product disclosed here to cushion a shortfall. Investors evaluating Zevra should treat MIPLYFFA's continued commercial performance as effectively synonymous with the company's near-term revenue trajectory, recognizing that the 82% concentration is a feature of an early-stage commercial launch rather than a diversified, multi-product revenue base.

For the engine’s reasoning on ZVRA’s current verdict — including which dimensions drove the score — see the per-dimension breakdown.

Industry peers · Biotechnology

Peer concentration profile

SymbolNameHIGHMEDIUMLOWTotal
ACADACADIA Pharmaceuticals Inc.2002
ABUSArbutus Biopharma Corporation1102
ABSIAbsci Corporation1001
ZVRAZevra Therapeutics, Inc.1001
ABCLAbCellera Biologics Inc.0000
ACHVAchieve Life Sciences, Inc.0000

Concentration counts reflect items disclosed in each peer’s most recent 10-K; disclosed-size classification uses TrendMatrix’s internal 10-K extraction taxonomy.

Concentration disclosures are extracted verbatim from SEC 10-K filings; the disclosed-size classification and the synthesis above are engine-derived. Size reflects how large each exposure is against fixed share thresholds (HIGH >50%, MEDIUM 25–50%, LOW <25% or an explicit diversification statement), not a judgment of how dangerous it is, and is not a buy/sell rating, a price target, or a view on the stock. Not a complete list of risk factors — see the full filing.

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