MIPLYFFA
“10-K Item 1A: 'For the year ended December 31, 2025 we derived approximately 82% of our revenues from commercial sales of MIPLYFFA'”
Updated
The most significant concentration Zevra Therapeutics discloses is MIPLYFFA at 82%, classified HIGH by disclosed size. Below: the full set from the latest 10-K — verbatim quotes, filing references, and a synthesis of what these exposures mean together.
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.
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Source: Zevra Therapeutics’s SEC Form 10-K filed — view the filing on SEC EDGAR ↗
Each card carries a disclosed-size chip (HIGH / MEDIUM / LOW — how large the exposure is as a share of revenue, not how dangerous it is) and a nature tag: Built-in(the company’s own model, geography, or products) or Outside party (an external customer, supplier, or distributor it relies on).
“10-K Item 1A: 'For the year ended December 31, 2025 we derived approximately 82% of our revenues from commercial sales of MIPLYFFA'”
Zevra Therapeutics' revenue is heavily concentrated in a single commercial product: approximately 82% of 2025 revenues were derived from commercial sales of MIPLYFFA, a high-share exposure with a mixed character, combining the structural fact of a single-product commercial base with the dependency-like sensitivity of that revenue to ongoing demand, pricing, and reimbursement dynamics for one drug. Because MIPLYFFA accounts for such a large share of the top line, any disruption to its commercial trajectory — whether from competitive entry, reimbursement changes, or manufacturing issues — would flow through to reported revenue with little offsetting diversification from other products. This single exposure is therefore the primary variable most capable of moving the verdict on Zevra, since there is no comparably sized second product disclosed here to cushion a shortfall. Investors evaluating Zevra should treat MIPLYFFA's continued commercial performance as effectively synonymous with the company's near-term revenue trajectory, recognizing that the 82% concentration is a feature of an early-stage commercial launch rather than a diversified, multi-product revenue base.
For the engine’s reasoning on ZVRA’s current verdict — including which dimensions drove the score — see the per-dimension breakdown.
| Symbol | Name | HIGH | MEDIUM | LOW | Total |
|---|---|---|---|---|---|
| ACAD | ACADIA Pharmaceuticals Inc. | 2 | 0 | 0 | 2 |
| ABUS | Arbutus Biopharma Corporation | 1 | 1 | 0 | 2 |
| ABSI | Absci Corporation | 1 | 0 | 0 | 1 |
| ZVRA● | Zevra Therapeutics, Inc. | 1 | 0 | 0 | 1 |
| ABCL | AbCellera Biologics Inc. | 0 | 0 | 0 | 0 |
| ACHV | Achieve Life Sciences, Inc. | 0 | 0 | 0 | 0 |
Concentration counts reflect items disclosed in each peer’s most recent 10-K; disclosed-size classification uses TrendMatrix’s internal 10-K extraction taxonomy.