HIGHBuilt-inPipeline
palazestrant
“10-K Item 1A: 'We are substantially dependent on the success of our lead product candidate, palazestrant, which is currently in clinical development.'”
OLMA · Concentration risk · 10-K extracted
Olema Pharmaceuticals (OLMA) concentration risks
Updated
The most significant concentration Olema Pharmaceuticals discloses is palazestrant, classified HIGH by disclosed size. Below: the full set from the latest 10-K — verbatim quotes, filing references, and a synthesis of what these exposures mean together.
Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.
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Source: Olema Pharmaceuticals’s SEC Form 10-K filed — view the filing on SEC EDGAR ↗
At a glance
Disclosed-size breakdown · 1 disclosed concentration
HIGH1
MEDIUM0
LOW0
Disclosed concentrations
Each card carries a disclosed-size chip (HIGH / MEDIUM / LOW — how large the exposure is as a share of revenue, not how dangerous it is) and a nature tag: Built-in(the company’s own model, geography, or products) or Outside party (an external customer, supplier, or distributor it relies on).
TrendMatrix Research · concentration synthesis
What these concentrations mean together
updated 2026-07-06Olema Pharmaceuticals' investment case rests on a single asset: the company states it is substantially dependent on the success of its lead product candidate, palazestrant, which is currently in clinical development. This is a high, structural concentration typical of a clinical-stage biopharmaceutical company with one lead program — value is not diversified across multiple approved products or revenue streams but instead hinges on the clinical, regulatory, and eventual commercial outcome of this single candidate. With no other concentration disclosed, palazestrant's development trajectory is effectively the entire thesis: positive trial results, regulatory progress, or a partnership could move the stock meaningfully in either direction, and there is no secondary program or revenue source to offset a setback. This is a common and expected profile for a company at this stage, but it does mean that clinical and regulatory catalysts around palazestrant specifically — rather than broader company-level diversification — are what will determine outcomes here.
For the engine’s reasoning on OLMA’s current verdict — including which dimensions drove the score — see the per-dimension breakdown.
Industry peers · Biotechnology
Peer concentration profile
| Symbol | Name | HIGH | MEDIUM | LOW | Total |
|---|---|---|---|---|---|
| ACAD | ACADIA Pharmaceuticals Inc. | 2 | 0 | 0 | 2 |
| ABUS | Arbutus Biopharma Corporation | 1 | 1 | 0 | 2 |
| ABSI | Absci Corporation | 1 | 0 | 0 | 1 |
| OLMA● | Olema Pharmaceuticals, Inc. | 1 | 0 | 0 | 1 |
| ABCL | AbCellera Biologics Inc. | 0 | 0 | 0 | 0 |
| ACHV | Achieve Life Sciences, Inc. | 0 | 0 | 0 | 0 |
Concentration counts reflect items disclosed in each peer’s most recent 10-K; disclosed-size classification uses TrendMatrix’s internal 10-K extraction taxonomy.