TransMedics Group, Inc. (TMDX) Stock Analysis
Recovery setup
Healthcare · Medical Devices
Sell if holding. Multiple concerning factors at $74.77: Leverage penalty (D/E 1.7): -1.0; Earnings estimates trending DOWN.
TransMedics develops the Organ Care System (OCS), the only FDA-approved portable multi-organ warm perfusion platform for heart, lung, and liver transplants, and provides the National OCS Program (NOP) as a turnkey outsourced procurement and logistics service. Revenue of $605.5M... Read more
Sell if holding. Multiple concerning factors at $74.77: Leverage penalty (D/E 1.7): -1.0; Earnings estimates trending DOWN. Chart setup: Death cross but MACD improving, RSI 62. Score 5.4/10, moderate confidence.
Passes 8/10 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 45d clear, semi cycle peak clear, materials cycle peak clear). Fails on death cross (50MA < 200MA). Suitability: aggressive.
About TransMedics Group, Inc.
About TransMedics Group, Inc.
Three FDA Pre-Market Approval (PMA)-cleared devices—OCS Heart, OCS Lung, and OCS Liver—form the commercial foundation of TransMedics Group, each approved for both donated-after-brain-death and donated-after-circulatory-death organ preservation. TransMedics generated $605.5 million in total revenue during 2025, up 37.1% from 2024, with substantially all revenue sourced from U.S. transplant centers. The company employed 898 people at December 31, 2025.
TransMedics commercializes the OCS through two channels: the National OCS Program (NOP), launched in 2021, which provides transplant centers with outsourced organ procurement, OCS perfusion management, and logistics via trained organ procurement surgeons and a fleet of 22 owned fixed-wing aircraft; and a direct acquisition model for a small number of U.S. centers and all international customers. Revenue is predominantly recurring—single-use OCS Perfusion Sets and OCS Solutions are required for every transplant using the platform—and Medicare reimburses the OCS under the organ acquisition cost mechanism on a reasonable cost basis, with nearly half of U.S. lung, heart, and liver transplants covered by Medicare and Medicaid. The company is developing OCS Kidney on a third-generation platform and enrolled two next-generation clinical trials for OCS Lung and OCS Heart in 2025. TransMedics reported net income of $190.3 million in 2025 and $35.5 million in 2024, after years of prior operating losses.
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TransMedics' entire manufacturing output flows through a single facility in Andover, Massachusetts. Simultaneously, all OCS disposable sets require third-party ethylene oxide sterilization before sale; the 10-K warns that regulatory restrictions on ethylene oxide, combined with limited sterilization alternatives, could halt product sales entirely until a qualified alternative vendor is secured, and notes that transitioning sterilization methods may not be possible in a timely or cost-effective manner, or at all. A disruption at either node could simultaneously shut down all product supply.
See also: Healthcare · Medical Devices
From TransMedics Group, Inc.'s most recent 10-K filing, extracted June 16, 2026.
Recent developments
updated 2026-06-15Recent Developments — TransMedics Group, Inc.
Latest news
- NEWS TransMedics (TMDX) Enters Agreement to Invest in PAD Aviation fo - GuruFocus — GuruFocus positive
- NEWS M&T Bank Corp Grows Stock Holdings in TransMedics Group, Inc. $TMDX - MarketBeat — MarketBeat neutral
- NEWS TransMedics Group Inc (TMDX) Shares Fall 6.3% -- What GF Score o - GuruFocus — GuruFocus negative
- NEWS TransMedics Group (TMDX) to Release Quarterly Earnings on Tuesday - MarketBeat — MarketBeat neutral
- NEWS Why TransMedics (TMDX) Is Up 8.2% After Record OCS Volumes And First Full Year Cash Flow - simplywall.st — simplywall.st positive
Generated 2026-06-17T09:12:26Z.
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Rating Breakdown
2 floor-breakers
Technicals below the gate floor. Component breakdown shows what dragged the score down.static
Growth below the gate floor. Component breakdown shows what dragged the score down.static
Price Targets
Position Sizing
Risk Alerts
Earnings
Verdict History
Frequently Asked Questions
Sell if holding. Multiple concerning factors at $74.77: Leverage penalty (D/E 1.7): -1.0; Earnings estimates trending DOWN. Chart setup: Death cross but MACD improving, RSI 62. Prior stop was $69.53. Score 5.4/10, moderate confidence.
Take-profit target: $101.60 (+35.9% upside). Prior stop was $69.53. Stop-loss: $69.53.
Leverage penalty (D/E 1.7): -1.0; Earnings estimates trending DOWN; Weak growth.
TransMedics Group, Inc. trades at a P/E of 16.7 (forward 22.1). TrendMatrix value score: 6.5/10. Verdict: Sell.
19 analysts cover TMDX with a consensus score of 4.0/5. Average price target: $117.
What does TransMedics Group, Inc. do?TransMedics develops the Organ Care System (OCS), the only FDA-approved portable multi-organ warm perfusion platform...
TransMedics develops the Organ Care System (OCS), the only FDA-approved portable multi-organ warm perfusion platform for heart, lung, and liver transplants, and provides the National OCS Program (NOP) as a turnkey outsourced procurement and logistics service. Revenue of $605.5M in 2025 (37% growth) is largely recurring from single-use OCS disposable sets.