Cencora, Cardinal Health, and McKesson
“10-K Item 1A: 'Cencora, Inc., Cardinal Health, Inc., and McKesson Corporation...collectively accounted for more than 76% of our total product revenue in 2025'”
Updated
The most significant concentration Supernus Pharmaceuticals discloses is Cencora, Cardinal Health, and McKesson at 76%, classified HIGH by disclosed size. Below: the full set from the latest 10-K — verbatim quotes, filing references, and a synthesis of what these exposures mean together.
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Source: Supernus Pharmaceuticals’s SEC Form 10-K filed — view the filing on SEC EDGAR ↗
Each card carries a disclosed-size chip (HIGH / MEDIUM / LOW — how large the exposure is as a share of revenue, not how dangerous it is) and a nature tag: Built-in(the company’s own model, geography, or products) or Outside party (an external customer, supplier, or distributor it relies on).
“10-K Item 1A: 'Cencora, Inc., Cardinal Health, Inc., and McKesson Corporation...collectively accounted for more than 76% of our total product revenue in 2025'”
“10-K Item 1A: 'Qelbree®...represented approximately 49%...of our total net revenues for the year ended December 31, 2025'”
“10-K Item 1A: 'GOCOVRI®...represented approximately...23%...of our total net revenues for the year ended December 31, 2025'”
The company's disclosed concentration profile combines a high-share distributor dependency and two product-level exposures of differing scale. On the customer side, three specialty pharmaceutical distributors — Cencora, Cardinal Health, and McKesson — collectively accounted for more than 76% of total product revenue in 2025, a high-share dependency. This channel concentration is characteristic of the U.S. specialty pharmaceutical market, where the "Big Three" wholesalers control the dominant share of distribution. The dependency character means that changes in purchasing terms, inventory management practices, or contract arrangements with any of these distributors could affect revenue timing and visibility. On the product side, Qelbree represented approximately 49% of total net revenues for the year ended December 31, 2025, a moderate-share, mixed-character exposure. As the company's largest product by revenue share, Qelbree's prescription volume, reimbursement dynamics, and competitive position are the single most important product-level driver of results. GOCOVRI contributed approximately 23% of total net revenues for the same period, a lower-share, mixed-character exposure that provides some product diversification but at a scale where a market share shift or generic entry would have a more limited aggregate impact than a similar event affecting Qelbree. The three exposures interact: the distributor concentration is the channel through which both Qelbree and GOCOVRI reach the market, meaning the company's revenue from its top two products flows almost entirely through three wholesale relationships. Any disruption — at the distributor, the product, or both — compounds given the lack of channel diversification.
For the engine’s reasoning on SUPN’s current verdict — including which dimensions drove the score — see the per-dimension breakdown.
| Symbol | Name | HIGH | MEDIUM | LOW | Total |
|---|---|---|---|---|---|
| ANIP | ANI Pharmaceuticals, Inc. | 2 | 1 | 0 | 3 |
| AMLX | Amylyx Pharmaceuticals, Inc. | 2 | 0 | 0 | 2 |
| SUPN● | Supernus Pharmaceuticals, Inc. | 1 | 1 | 1 | 3 |
| AMRX | Amneal Pharmaceuticals, Inc. | 1 | 1 | 0 | 2 |
| BCRX | BioCryst Pharmaceuticals, Inc. | 0 | 2 | 0 | 2 |
| ALKS | Alkermes plc | 0 | 1 | 1 | 2 |
Concentration counts reflect items disclosed in each peer’s most recent 10-K; disclosed-size classification uses TrendMatrix’s internal 10-K extraction taxonomy.