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SANASana Biotechnology, Inc.Sell5.1·$4.07+14.33%
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Sana Biotechnology, Inc. (SANA) Stock Analysis

Recovery setup · Inst Constrain edge

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $4.07: Quality below floor (1.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.1/10 and A.R:R 5.7:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Below-average business quality.

Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United States. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including type 1 diabetes, B cell... Read more

$4.07+86.0% A.UpsideScore 5.1/10#134 of 258 Biotechnology
QualityF-score2 / 9FCF yield-2.66%
Stop $3.73Target $7.46(analyst − 13%)A.R:R 5.7:1
Analyst target$8.57+110.6%7 analysts
$7.46our TP
$4.07price
$8.57mean
$12

Sell if holding. Engine safety override at $4.07: Quality below floor (1.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.1/10 and A.R:R 5.7:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Below-average business quality. Chart setup: Death cross but MACD improving, RSI 87. Score 5.1/10, moderate confidence.

Passes 7/8 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, earnings proximity 38d clear, semi cycle peak clear, materials cycle peak clear). Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-05

Recent Developments — Sana Biotechnology, Inc.

Generated 2026-07-05T07:10:32Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Tue, Aug 11, 202638d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Quality below floor (1.2 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-7.7
Mkt Cap$1.1B
EV/EBITDA-6.5
Profit Mgn0.0%
ROE-147.4%
Rev Growth
Beta2.14
DividendNone
Rating analysts15

Quality Signals

Piotroski F2/9

Options Flow

P/C0.60bullish
IV157%elevated

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Performance. Past performance is not indicative of future results. Performance figures reflect the published model only and do not reflect any individual subscriber's actual results.

Methodology · Editorial policy & full disclaimer

Rating Breakdown

4 floor-breakers·1 ceiling hit

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roe
0.0
Roa
0.0
Gross Margin
0.0
Operating Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
2.2
Moat
4.0
Current Ratio
4.9
Cash-burning (FCF negative)No competitive moatWeak Piotroski F-Score: 2/9Quality concerns

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
0.0
Support Resistance
0.1
52w Position
2.2
Gap
5.0

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.0
Value Rank
5.0
Growth Rank
5.0

Volatile — 6.0% daily ATR makes tight stops impractical. Position-size conservatively.static

Days To Cover
0.0
Volatility
0.0
Implied Vol
0.0
Short Interest
0.9
Beta
2.9
Debt Equity
6.8
Put Call
9.3
High short interest justified: 26%High IV: 157%
GatesDeath cross (50MA < 200MA)Momentum 7.0>=5.5A.R:R 5.7 ≥ 1.5Insider activity: OKNo SEC red flagsEARNINGS PROXIMITY 38d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRecoverySuitability: Speculative
RSI
87 · Overbought
20D MA 50D MA 200D MADEATH CROSSSupport $2.61Resistance $4.02

Price Targets

$4
$7
A.Upside+83.3%
A.R:R5.7:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (1.2 < 4.0)

Earnings

B
B
M
M
2/4 beats
Next Earnings2026-08-11 (38d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is SANA stock a buy right now?

Sell if holding. Engine safety override at $4.07: Quality below floor (1.2 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.1/10 and A.R:R 5.7:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 26%; Below-average business quality. Chart setup: Death cross but MACD improving, RSI 87. Prior stop was $3.73. Score 5.1/10, moderate confidence.

What is the SANA stock price target?

Take-profit target: $7.46 (+86.0% upside). Prior stop was $3.73. Stop-loss: $3.73.

What are the risks of investing in SANA?

Quality below floor (1.2 < 4.0).

Is SANA overvalued or undervalued?

Sana Biotechnology, Inc. trades at a P/E of N/A (forward -7.7). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about SANA?

15 analysts cover SANA with a consensus score of 4.3/5. Average price target: $9.

What does Sana Biotechnology, Inc. do?Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United...

Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines in the United States. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including type 1 diabetes, B cell mediated autoimmune diseases, and oncology. The company's product pipeline includes UP421, a HIP-modified allogeneic primary islet cell product, which is in phase 1 clinical trial to treat type 1 diabetes; SC451, a HIP-modified, stem cell derived pancreatic islet cell therapy, which is in preclinical trial for the treatment of type 1 diabetes; SG293 and SG299, a CD8-targeted fusosome for the treatment of B cell hematologic malignancies and B cell mediated autoimmune diseases. The company has an option and license agreement with Beam Therapeutics Inc. for use of Beam's proprietary CRISPR Cas12b nuclease editing technology to research, develop, and commercialize engineered cell therapy products; and a license agreement with Harvard College to access certain intellectual property for the development of hypoimmune-modified cells. The company has a strategic collaboration with Mayo Clinic for the development of SC451, a hypoimmune-modified pancreatic islet cell therapy for type 1 diabetes. The company was formerly known as FD Therapeutics, Inc. and changed its name to Sana Biotechnology, Inc. in September 2018. Sana Biotechnology, Inc. was incorporated in 2018 and is headquartered in Seattle, Washington.

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