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Precigen, Inc. (PGEN) Stock Analysis

Breakout setup

SellVALUE-TRAP 1/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $4.20: Quality below floor (2.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.3/10 and A.R:R 8.5:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 17%; Elevated put/call ratio: 1.33; Below-average business quality.

Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. The company offers therapeutic platforms consisting... Read more

$4.20+91.9% A.UpsideScore 4.3/10#138 of 158 Biotechnology
Stop $3.91Target $8.07(analyst − 15%)A.R:R 8.5:1
Analyst target$9.50+126.2%2 analysts
$8.07our TP
$4.20price
$9.50mean
$10

Sell if holding. Engine safety override at $4.20: Quality below floor (2.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.3/10 and A.R:R 8.5:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 17%; Elevated put/call ratio: 1.33; Below-average business quality. Chart setup: Golden cross, above all MAs, RSI 52, MACD bullish. Score 4.3/10, moderate confidence.

Passes 6/7 gates (positive momentum, favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, semi cycle peak clear). Suitability: aggressive.

Thesis

Rewards
No bull case signals
Risks
Quality below floor (2.6 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-18.7
Mkt Cap$1.5B
EV/EBITDA-14.1
Profit Mgn0.0%
ROE-572.0%
Rev Growth283.6%
Beta1.12
DividendNone
Rating analysts9

Quality Signals

Piotroski F3/9

Options Flow

P/C1.33bearish
IV104%elevated
Max Pain$1-76.2% vs spot

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

5 floor-breakers

Volatile — 5.1% daily ATR makes tight stops impractical. Position-size conservatively.static

Volatility
0.0
Implied Vol
0.0
Debt Equity
0.3
Short Interest
1.8
Max Pain Risk
3.0
Days To Cover
3.2
Put Call
4.4
Beta
6.5
High short interest justified: 17%High IV: 104%Above max pain $1

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Roa
0.0
Gross Margin
0.0
Net Margin
0.0
Fcf Quality
0.0
Piotroski F
3.3
Moat
5.0
Current Ratio
9.9
Cash-burning: FCF -551% of revenueNo competitive moatWeak Piotroski F-Score: 3/9Quality concerns

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Surprise Avg
0.0
Earnings History
1.1
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/2MEarnings in 14 days

Technicals below the gate floor. Component breakdown shows what dragged the score down.static

Bollinger
1.7
Support Resistance
2.7
52w Position
5.4

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.0
Value Rank
5.0
Growth Rank
9.4
Industry growth leader
GatesEARNINGS PROXIMITY 14d<=14d (soft)Momentum 6.2>=5.5A.R:R 8.5 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTSEMI CYCLE PEAK CLEARBreakoutSuitability: Aggressive
RSI
52 · Neutral
20D MA 50D MA 200D MAGOLDEN CROSSSupport $3.75Resistance $4.37

Price Targets

$4
$8
A.Upside+92.1%
A.R:R8.5:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (2.6 < 4.0)

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-05-14 (14d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is PGEN stock a buy right now?

Sell if holding. Engine safety override at $4.20: Quality below floor (2.6 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 4.3/10 and A.R:R 8.5:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 17%; Elevated put/call ratio: 1.33; Below-average business quality. Chart setup: Golden cross, above all MAs, RSI 52, MACD bullish. Prior stop was $3.91. Score 4.3/10, moderate confidence.

What is the PGEN stock price target?

Take-profit target: $8.07 (+91.9% upside). Prior stop was $3.91. Stop-loss: $3.91.

What are the risks of investing in PGEN?

Quality below floor (2.6 < 4.0).

Is PGEN overvalued or undervalued?

Precigen, Inc. trades at a P/E of N/A (forward -18.7). TrendMatrix value score: 5.0/10. Verdict: Sell.

What do analysts say about PGEN?

9 analysts cover PGEN with a consensus score of 4.0/5. Average price target: $10.

What does Precigen, Inc. do?Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using...

Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. The company offers therapeutic platforms consisting of AdenoVerse platform, which utilizes a library of proprietary adenovectors for gene delivery of therapeutic effectors, immunomodulators, and vaccine antigen; and UltraCAR-T to provide chimeric antigen receptor T cell therapies for cancer patients. It also develops programs based on the UltraCAR-T platform, including PRGN-3005 in Phase 1/1b clinical trial to treat advanced ovarian, fallopian tube, or primary peritoneal cancer; PRGN-3006 in Phase 1b trial for patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndromes; and PRGN-3007 in Phase 1/1b trial for the treatment of advanced receptor tyrosine kinase-like orphan receptor 1-positive, hematologic, and solid tumors. In addition, the company is developing programs based on the AdenoVerse immunotherapy platform comprising PRGN-2009 in Phase 2 trial for patients with HPV+ solid tumors; and PRGN-2012 in Phase ½ trial to treat recurrent respiratory papillomatosis. Further, it provides UltraPorator, a proprietary electroporation device. The company was formerly known as Intrexon Corporation and changed its name to Precigen, Inc. in February 2020. Precigen, Inc. was founded in 1998 and is headquartered in Germantown, Maryland.

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