Skip to main content

Insmed Incorporated (INSM) Stock Analysis

Falling Knife setup

SellVALUE-TRAP 3/5Moderate Confidence

Healthcare · Biotechnology

Sell if holding. Momentum 1.9/10 is below the 5.0 floor at $107.47 — engine's falling-knife protection flags exit rather than catching a breakdown. Specifics: Concentration risk — Product: ARIKAYCE and BRINSUPRI; V7 low-quality RISK_OFF penalty: -0.5 (Q=4.9).

Insmed is a global biopharmaceutical company with two commercial products: ARIKAYCE (amikacin liposome inhalation suspension) approved for refractory MAC lung disease in the US, EU, and Japan, and BRINSUPRI (brensocatib) approved for non-cystic fibrosis bronchiectasis in the US... Read more

$107.47+68.4% A.UpsideScore 5.1/10#82 of 157 Biotechnology
QualityF-score5 / 9FCF yield-2.60%
Stop $99.89Target $180.90(analyst − 10%)A.R:R 4.6:1
Analyst target$201.00+87.0%20 analysts
$180.90our TP
$107.47price
$201.00mean
$243

Sell if holding. Momentum 1.9/10 is below the 5.0 floor at $107.47 — engine's falling-knife protection flags exit rather than catching a breakdown. Specifics: Concentration risk — Product: ARIKAYCE and BRINSUPRI; V7 low-quality RISK_OFF penalty: -0.5 (Q=4.9). Chart setup: Death cross, below all MAs, RSI 32, MACD bearish. Score 5.1/10, moderate confidence.

Passes 7/8 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news boost analyst 0.40, earnings proximity 78d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: moderate.

Recent Developments — Insmed Incorporated

Generated 2026-05-20T21:06:21Z.

Thesis

Rewards
Sector modifier (Healthcare): +0.5
Strong growth profile
Analyst upside: 68%
Risks
Concentration risk — Product: ARIKAYCE and BRINSUPRI
V7 low-quality RISK_OFF penalty: -0.5 (Q=4.9)
Leverage penalty (D/E 1.1): -0.5

Key Metrics

P/E (TTM)
P/E (Fwd)291.2
Mkt Cap$23.3B
EV/EBITDA-24.0
Profit Mgn-144.4%
ROE-294.5%
Rev Growth229.6%
Beta0.89
DividendNone
Rating analysts28

Quality Signals

Piotroski F5/9MoatNarrow

Options Flow

P/C1.19bearish
IV54%elevated
Max Pain$70-34.9% vs spot

Concentration Risks(10-K Item 1A)

  • HIGHProductARIKAYCE and BRINSUPRI
    10-K Item 1A: 'Our prospects are highly dependent on the success of our approved products, ARIKAYCE and BRINSUPRI'

Material Events(8-K, last 90d)

  • 2026-02-19Item 5.02LOW
    David W.J. McGirr, board member and Audit Committee chair, notified the board on February 17, 2026 that he will not stand for re-election at the 2026 Annual Meeting. Will serve until the meeting. Decision not a result of any disagreement.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers·1 ceiling hit

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Macd
0.0
Obv
1.0
Ma Position
2.2
Volume
3.0
Rsi
3.5
Volume distribution (falling OBV)Below 200-MA but MA still rising (+3.1%/30d) — pullback in uptrend, not confirmed weakness

Ranks in the bottom of its industry peers on the composite signal. Better names in the same sector exist.static

Quality Rank
0.0
Value Rank
1.8
Growth Rank
9.6
Industry growth leader

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
News Activity
6.0
Earnings concerns: 1B/3M

Priced at a premium — multiples above sector norms. Needs delivery on growth + margins to justify.static

Ps
0.0
Peg Ratio
3.9
Analyst Target
9.0
PEG: 2.74
GatesMomentum 1.9<4.5A.R:R 4.6 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS BOOST ANALYST 0.40EARNINGS PROXIMITY 78d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARFalling KnifeSuitability: Moderate
RSI
32 · Neutral
20D MA 50D MA 200D MADEATH CROSSSupport $98.90Resistance $145.43

Price Targets

$100
$181
A.Upside+68.3%
A.R:R4.6:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeRisk-Off

Risk Alerts

! Momentum score 1.9/10 — below 4.5 minimum

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-06 (78d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is INSM stock a buy right now?

Sell if holding. Momentum 1.9/10 is below the 5.0 floor at $107.47 — engine's falling-knife protection flags exit rather than catching a breakdown. Specifics: Concentration risk — Product: ARIKAYCE and BRINSUPRI; V7 low-quality RISK_OFF penalty: -0.5 (Q=4.9). Chart setup: Death cross, below all MAs, RSI 32, MACD bearish. Prior stop was $99.89. Score 5.1/10, moderate confidence.

What is the INSM stock price target?

Take-profit target: $180.90 (+68.4% upside). Prior stop was $99.89. Stop-loss: $99.89.

What are the risks of investing in INSM?

Concentration risk — Product: ARIKAYCE and BRINSUPRI; V7 low-quality RISK_OFF penalty: -0.5 (Q=4.9); Leverage penalty (D/E 1.1): -0.5.

Is INSM overvalued or undervalued?

Insmed Incorporated trades at a P/E of N/A (forward 291.2). TrendMatrix value score: 3.9/10. Verdict: Sell.

What do analysts say about INSM?

28 analysts cover INSM with a consensus score of 4.3/5. Average price target: $201.

What does Insmed Incorporated do?Insmed is a global biopharmaceutical company with two commercial products: ARIKAYCE (amikacin liposome inhalation...

Insmed is a global biopharmaceutical company with two commercial products: ARIKAYCE (amikacin liposome inhalation suspension) approved for refractory MAC lung disease in the US, EU, and Japan, and BRINSUPRI (brensocatib) approved for non-cystic fibrosis bronchiectasis in the US (August 2025) and EU (November 2025). The pipeline includes TPIP (PH-ILD/PAH) in Phase 3 and gene therapy programs for DMD and ALS. The company has no history of profitability.

Related stocks: INCY (Incyte Corporation) · ARGX (argenx SE) · HALO (Halozyme Therapeutics, Inc.) · EXEL (Exelixis, Inc.) · CAI (Caris Life Sciences, Inc.)