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AKTSAktis Oncology, Inc.Sell5.8·$28.20-11.22%
SellModerate Confidence
Investment thesis

Aktis Oncology is growing revenue at 123% year-over-year with favorable analyst sentiment and 37% upside to the consensus target — but quality metrics fall below the minimum threshold for entry, earnings have missed three of the past four quarters, and a 17% short interest adds downside risk if clinical momentum stalls.

Thesis pillars

  • Quality Below Minimum Entry ThresholdStable
  • Exceptional Revenue Growth RateStable
  • Persistent Earnings MissesStable
  • +1 more pillar — see the Why tab for full reasoning

Full reasoning →

Open full analysis

Aktis Oncology, Inc. (AKTS) Stock Analysis

Range Bound setup

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $28.20: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10. Specifically: High short interest: 18%; Below-average business quality.

Aktis Oncology is a clinical-stage biotechnology company developing miniprotein radioconjugates that deliver alpha-emitting radioisotopes to solid tumors, with lead candidate [225Ac]Ac-AKY-1189 targeting Nectin-4-expressing cancers in a Phase 1b trial. The company has not... Read more

$28.20+11.0% A.UpsideScore 5.8/10#42 of 253 Biotechnology
QualityF-score4 / 9FCF yield
Stop $24.70Target $29.47(analyst − 13%)A.R:R 0.7:1
Analyst target$33.88+20.1%6 analysts
$29.47our TP
$28.20price
$33.88mean
$40

Sell if holding. Engine safety override at $28.20: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10. Specifically: High short interest: 18%; Below-average business quality. Chart setup: RSI 60 mid-range, Bollinger mid-band. Score 5.8/10, moderate confidence.

Passes 6/8 gates (positive momentum, clean insider activity, news events none recent, earnings proximity 39d clear, semi cycle peak clear, materials cycle peak clear). Fails on favorable risk/reward ratio. Suitability: speculative.

news + 30-day 8-K events · 5-min refresh

Recent developments

updated 2026-07-07

Recent Developments — Aktis Oncology, Inc.

Generated 2026-07-07T09:31:41Z.

TrendMatrix Research · upcoming catalyst calendar

Upcoming dated catalysts

Thu, Aug 13, 202639d to earnings· next earnings call

Thesis

Rewards
No bull case signals
Risks
Concentration risk — Pipeline: lead product candidate [225Ac]Ac-AKY-1189
Quality below floor (2.9 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-16.4
Mkt Cap$1.8B
EV/EBITDA-16.0
Profit Mgn0.0%
ROE
Rev Growth123.0%
Beta
DividendNone
Rating analysts12

Quality Signals

Piotroski F4/9

Concentration Risks(10-K Item 1A)

  • HIGHpipelinelead product candidate [225Ac]Ac-AKY-1189
    10-K Item 1A: 'Our business is highly dependent on our lead product candidate, [225Ac]Ac-AKY-1189, for the treatment of Nectin-4 expressing tumors.'

Material Events(8-K, last 90d)

  • 2026-04-16Item 5.02LOW
    Board appointed Glenn Gormley, MD, PhD as a Class I director effective April 15, 2026, and named him Co-Chair of the newly created Science and Technology Committee. Routine board appointment; no departure involved.
    SEC filing →

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results.

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Methodology · Editorial policy & full disclaimer

Rating Breakdown

3 floor-breakers·1 ceiling hit

Volatile — 11.7% daily ATR makes tight stops impractical. Position-size conservatively.static

Days To Cover
0.0
Volatility
0.0
Short Interest
0.8
Debt Equity
2.7
High short interest: 18%Concentration risks: 1 HIGH (10-K Item 1A — sized via position_sizing, validated via buy_confidence)

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Gross Margin
0.0
Net Margin
0.0
Piotroski F
4.4
Current Ratio
5.0
Moat
5.0
No competitive moatQuality concerns

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
News Activity
8.0
Earnings concerns: 1B/3M
GatesA.R:R 0.7 < 1.5@spotExecutive change: officer departure/appointmentMomentum 7.9>=5.5Insider activity: OKNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 39d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARRange BoundSuitability: Speculative
RSI
60 · Neutral
20D MA 50D MA 200D MASupport $18.25Resistance $34.19

Price Targets

$25
$29
A.Upside+4.5%
A.R:R0.7:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (2.9 < 4.0)
! asymmetry at 0.7 (below the engine's 1.5 threshold)@spot

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-13 (39d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AKTS stock a buy right now?

Sell if holding. Engine safety override at $28.20: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.8/10. Specifically: High short interest: 18%; Below-average business quality. Chart setup: RSI 60 mid-range, Bollinger mid-band. Prior stop was $24.70. Score 5.8/10, moderate confidence.

What is the AKTS stock price target?

Take-profit target: $29.47 (+11.0% upside). Prior stop was $24.70. Stop-loss: $24.70.

What are the risks of investing in AKTS?

Concentration risk — Pipeline: lead product candidate [225Ac]Ac-AKY-1189; Quality below floor (2.9 < 4.0).

Is AKTS overvalued or undervalued?

Aktis Oncology, Inc. trades at a P/E of N/A (forward -16.4). TrendMatrix value score: 6.0/10. Verdict: Sell.

What do analysts say about AKTS?

12 analysts cover AKTS with a consensus score of 4.3/5. Average price target: $34.

What does Aktis Oncology, Inc. do?Aktis Oncology is a clinical-stage biotechnology company developing miniprotein radioconjugates that deliver...

Aktis Oncology is a clinical-stage biotechnology company developing miniprotein radioconjugates that deliver alpha-emitting radioisotopes to solid tumors, with lead candidate [225Ac]Ac-AKY-1189 targeting Nectin-4-expressing cancers in a Phase 1b trial. The company has not generated product revenue and funds operations through equity financings and a May 2024 discovery collaboration with Eli Lilly, which paid a $60.0 million upfront fee and could contribute up to $1.2 billion in milestones. Aktis held $226.8 million in cash as of December 31, 2025, plus $335.3 million in IPO proceeds from its J

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