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Aktis Oncology, Inc. (AKTS) Stock Analysis

SellModerate Confidence

Healthcare · Biotechnology

Sell if holding. Engine safety override at $18.50: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.9/10 and A.R:R 4.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Below-average business quality; Negative price momentum.

Aktis Oncology, Inc., a clinical-stage oncology company, engages in the research, development, and commercialization of targeted radiopharmaceuticals to treat various solid tumor cancers. The company's lead product candidate includes [225Ac]Ac-AKY-1189, a miniprotein... Read more

$18.50+52.4% A.UpsideScore 5.9/10#29 of 157 Biotechnology
QualityF-score4 / 9FCF yield
Stop $17.34Target $28.19(analyst − 13%)A.R:R 4.1:1
Analyst target$32.40+75.1%5 analysts
$28.19our TP
$18.50price
$32.40mean
$34

Sell if holding. Engine safety override at $18.50: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.9/10 and A.R:R 4.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Below-average business quality; Negative price momentum. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Score 5.9/10, moderate confidence.

Passes 7/8 gates (favorable risk/reward ratio, clean insider activity, no SEC red flags, news events none recent, earnings proximity 86d clear, semi cycle peak clear, materials cycle peak clear). Fails on weak momentum. Suitability: aggressive.

Recent Developments — Aktis Oncology, Inc.

Generated 2026-05-20T20:21:21Z.

Thesis

Rewards
No bull case signals
Risks
Quality below floor (2.9 < 4.0)

Key Metrics

P/E (TTM)
P/E (Fwd)-9.5
Mkt Cap$1.0B
EV/EBITDA-6.5
Profit Mgn0.0%
ROE
Rev Growth123.0%
Beta
DividendNone
Rating analysts12

Quality Signals

Piotroski F4/9

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. Full disclaimer

Rating Breakdown

4 floor-breakers·2 ceiling hits

Volatile — 6.4% daily ATR makes tight stops impractical. Position-size conservatively.static

Volatility
0.0
Short Interest
1.9
Days To Cover
2.2
Debt Equity
2.7
High short interest: 16%

No near-term catalyst priced in. Thesis progression will come from fundamentals grinding, not event reaction.static

Earnings History
0.0
Surprise Avg
0.0
Erm
5.0
Earnings Timing
5.0
Earnings concerns: 1B/3M

Price action weak — below key moving averages, no momentum carry. Needs a base before trend-continuation setups apply.static

Obv
1.0
Macd
1.7
Ma Position
2.5
Volume
3.4
Rsi
4.5
Volume distribution (falling OBV)

Quality below the gate floor. Component breakdown shows what dragged the score down.static

Gross Margin
0.0
Net Margin
0.0
Piotroski F
4.4
Current Ratio
5.0
Moat
5.0
No competitive moatQuality concerns
GatesMomentum 2.6<4.5A.R:R 4.1 ≥ 1.5Insider activity: OKNo SEC red flagsNEWS EVENTS NONE RECENTEARNINGS PROXIMITY 86d clearSEMI CYCLE PEAK CLEARMATERIALS CYCLE PEAK CLEARSuitability: Aggressive
RSI
48 · Neutral
20D MA 50D MA 200D MASupport $17.88Resistance $23.05

Price Targets

$17
$28
A.Upside+52.4%
A.R:R4.1:1

Position Sizing

ConvictionNone
Suggested %0.5%
Max %1%
RegimeSteady

Risk Alerts

! Quality below floor (2.9 < 4.0)
! Momentum score 2.6/10 — below 4.5 minimum

Earnings

B
M
M
M
1/4 beats
Next Earnings2026-08-13 (86d)

Verdict History

reverse chrono — latest first
Loading history...
Verdicts are recorded on every nightly pipeline run. Rows capture transitions (verdict flips, score deltas ≥0.3, entry/TP/SL changes). Rows with a ▶ can be expanded to see the change reason. Aggregate cohort performance is tracked in the recommendation ledger.
Frequently Asked Questions
Is AKTS stock a buy right now?

Sell if holding. Engine safety override at $18.50: Quality below floor (2.9 < 4.0) triggers a hard block regardless of the otherwise-positive setup — overall score 5.9/10 and A.R:R 4.1:1 is above the 1.5:1 BUY gate. Specifically: High short interest: 16%; Below-average business quality; Negative price momentum. Chart setup: No recognized chart pattern (not a breakout, bounce, continuation, recovery, falling knife, or range) — technicals mixed. Prior stop was $17.34. Score 5.9/10, moderate confidence.

What is the AKTS stock price target?

Take-profit target: $28.19 (+52.4% upside). Prior stop was $17.34. Stop-loss: $17.34.

What are the risks of investing in AKTS?

Quality below floor (2.9 < 4.0).

Is AKTS overvalued or undervalued?

Aktis Oncology, Inc. trades at a P/E of N/A (forward -9.5). TrendMatrix value score: 9.0/10. Verdict: Sell.

What do analysts say about AKTS?

12 analysts cover AKTS with a consensus score of 4.3/5. Average price target: $32.

What does Aktis Oncology, Inc. do?Aktis Oncology, Inc., a clinical-stage oncology company, engages in the research, development, and commercialization of...

Aktis Oncology, Inc., a clinical-stage oncology company, engages in the research, development, and commercialization of targeted radiopharmaceuticals to treat various solid tumor cancers. The company's lead product candidate includes [225Ac]Ac-AKY-1189, a miniprotein radioconjugate platform which is in ongoing Phase 1b clinical trial for the treatment of Nectin-4 expressing solid tumors, including locally advanced or metastatic urothelial cancer, breast cancer, NSCLC, colorectal cancer and cervical cancer; and [225Ac]Ac-AKY-2519 to deliver 225Ac to B7-H3 (CD276) expressing tumors, including prostate, lung and other solid tumors. It has license and collaboration agreements with Protein Innovation, Inc., TRIUMF Innovations, Inc., and Eli Lilly. The company was formerly known as HotKnot Therapeutics, Inc. and changed its name to Aktis Oncology, Inc. in April 2020. Aktis Oncology, Inc. was incorporated in 2020 and is headquartered in Boston, Massachusetts.

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