HIGHBuilt-in & outside partyPipeline
varegacestat
“10-K Item 1A: 'other than varegacestat, which recently completed the Phase 3 RINGSIDE trial, and IM-1021 and IM-3050, which are Phase 1 clinical assets'”
IMNM · Concentration risk · 10-K extracted
Immunome (IMNM) concentration risks
Updated
The most significant concentration Immunome discloses is varegacestat, classified HIGH by disclosed size. Below: the full set from the latest 10-K — verbatim quotes, filing references, and a synthesis of what these exposures mean together.
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Source: Immunome’s SEC Form 10-K filed — view the filing on SEC EDGAR ↗
At a glance
Disclosed-size breakdown · 1 disclosed concentration
HIGH1
MEDIUM0
LOW0
Disclosed concentrations
Each card carries a disclosed-size chip (HIGH / MEDIUM / LOW — how large the exposure is as a share of revenue, not how dangerous it is) and a nature tag: Built-in(the company’s own model, geography, or products) or Outside party (an external customer, supplier, or distributor it relies on).
TrendMatrix Research · concentration synthesis
What these concentrations mean together
updated 2026-07-03The company's disclosed concentration profile is narrow and centered on a single pipeline asset. Varegacestat, which recently completed the Phase 3 RINGSIDE trial, is identified alongside IM-1021 and IM-3050 as the company's principal clinical programs, and by disclosed size varegacestat represents a high-share concentration within the portfolio. The character of this exposure is mixed: it is partly structural, in that the company has made a deliberate strategic bet on a particular mechanism and indication, and partly idiosyncratic, in that the outcome of a single pivotal trial can materially reset the company's valuation and development pathway. Because no other approved product or advanced-stage asset is disclosed, the concentration is effectively enterprise-level rather than merely a pipeline weighting. A regulatory decision, a trial readout, or a commercialization outcome for varegacestat would affect the large majority of the company's near-term value in either direction. The two Phase 1 assets provide some optionality but are at an early stage where contribution to near-term enterprise value is limited. There is no disclosed customer, geographic, or supplier concentration to compound this pipeline exposure. The dominant concentration risk to monitor is therefore clinical and regulatory: the binary nature of late-stage trial outcomes for the lead program.
For the engine’s reasoning on IMNM’s current verdict — including which dimensions drove the score — see the per-dimension breakdown.
Industry peers · Biotechnology
Peer concentration profile
| Symbol | Name | HIGH | MEDIUM | LOW | Total |
|---|---|---|---|---|---|
| ACAD | ACADIA Pharmaceuticals Inc. | 2 | 0 | 0 | 2 |
| ACLX | Arcellx, Inc. | 1 | 1 | 0 | 2 |
| AGIO | Agios Pharmaceuticals, Inc. | 1 | 0 | 0 | 1 |
| ALMS | Alumis Inc. | 1 | 0 | 0 | 1 |
| IMNM● | Immunome, Inc. | 1 | 0 | 0 | 1 |
| ADMA | ADMA Biologics Inc | 0 | 1 | 0 | 1 |
Concentration counts reflect items disclosed in each peer’s most recent 10-K; disclosed-size classification uses TrendMatrix’s internal 10-K extraction taxonomy.