EDIT-401
“10-K Item 1A: 'We are dependent on the success of our lead product candidate, EDIT-401 ... our business is significantly dependent upon this one product candidate'”
Updated
The most significant concentration Editas Medicine discloses is EDIT-401, classified HIGH by disclosed size. Below: the full set from the latest 10-K — verbatim quotes, filing references, and a synthesis of what these exposures mean together.
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Source: Editas Medicine’s SEC Form 10-K filed — view the filing on SEC EDGAR ↗
Each card carries a disclosed-size chip (HIGH / MEDIUM / LOW — how large the exposure is as a share of revenue, not how dangerous it is) and a nature tag: Built-in(the company’s own model, geography, or products) or Outside party (an external customer, supplier, or distributor it relies on).
“10-K Item 1A: 'We are dependent on the success of our lead product candidate, EDIT-401 ... our business is significantly dependent upon this one product candidate'”
Editas Medicine's disclosed concentration risk is a single-asset dependency: the company states it is dependent on the success of its lead product candidate, EDIT-401, and that its business is significantly dependent upon this one product candidate. This is a structural rather than counterparty-driven exposure — it isn't a supplier or customer relationship that could be renegotiated or replaced, but the company's entire near-term value proposition resting on one clinical program. With no other concentration exposures disclosed, there is nothing to offset or diversify this risk within the filing; a clinical setback for EDIT-401 would directly and fully affect the company, since there is no second program, customer base, or geographic spread mentioned to cushion it. The high disclosed share underscores that this is not a minor or hedged risk. For a clinical-stage gene-editing company, this single-candidate dependency is a common shape of risk, but the lack of any additional disclosed exposures also means the filing offers no additional texture — the entire concentration story for Editas, as filed, is this one program.
For the engine’s reasoning on EDIT’s current verdict — including which dimensions drove the score — see the per-dimension breakdown.
| Symbol | Name | HIGH | MEDIUM | LOW | Total |
|---|---|---|---|---|---|
| ACAD | ACADIA Pharmaceuticals Inc. | 2 | 0 | 0 | 2 |
| ABUS | Arbutus Biopharma Corporation | 1 | 1 | 0 | 2 |
| ABSI | Absci Corporation | 1 | 0 | 0 | 1 |
| EDIT● | Editas Medicine, Inc. | 1 | 0 | 0 | 1 |
| ABCL | AbCellera Biologics Inc. | 0 | 0 | 0 | 0 |
| ACHV | Achieve Life Sciences, Inc. | 0 | 0 | 0 | 0 |
Concentration counts reflect items disclosed in each peer’s most recent 10-K; disclosed-size classification uses TrendMatrix’s internal 10-K extraction taxonomy.