COMP360 psilocybin treatment (sole clinical program)
“10-K Item 1: 'We are currently focusing our efforts on progressing our Phase 3 clinical program in TRD and our Phase 2b/3 clinical trial in PTSD.'”
Updated
The most significant concentration COMPASS Pathways Plc - American discloses is COMP360 psilocybin treatment (sole clinical program), classified HIGH by disclosed size. Below: the full set from the latest 10-K — verbatim quotes, filing references, and a synthesis of what these exposures mean together.
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Source: COMPASS Pathways Plc - American’s SEC Form 10-K filed — view the filing on SEC EDGAR ↗
Each card carries a disclosed-size chip (HIGH / MEDIUM / LOW — how large the exposure is as a share of revenue, not how dangerous it is) and a nature tag: Built-in(the company’s own model, geography, or products) or Outside party (an external customer, supplier, or distributor it relies on).
“10-K Item 1: 'We are currently focusing our efforts on progressing our Phase 3 clinical program in TRD and our Phase 2b/3 clinical trial in PTSD.'”
COMPASS Pathways' concentration risk is essentially total and pipeline-driven: the company is focusing its efforts on a single clinical program, COMP360 psilocybin treatment, currently progressing through a Phase 3 trial in treatment-resistant depression and a Phase 2b/3 trial in PTSD, a high, structural concentration. With no other named product candidate disclosed in these sources, the entire investment case rests on the outcome of COMP360's trials across its two indications. This is the defining characteristic of a single-asset clinical-stage company: there is no secondary program to offset a negative trial readout in either TRD or PTSD, and a delay or failure in either indication would directly affect the company's near-term trajectory since both indications share the same underlying compound. Because the disclosed exposure is structural rather than a dependency on a specific counterparty or customer, the risk is best understood as binary clinical and regulatory risk concentrated in one compound, rather than a relationship that could be renegotiated or replaced.
For the engine’s reasoning on CMPS’s current verdict — including which dimensions drove the score — see the per-dimension breakdown.
| Symbol | Name | HIGH | MEDIUM | LOW | Total |
|---|---|---|---|---|---|
| ACHC | Acadia Healthcare Company, Inc. | 1 | 1 | 0 | 2 |
| CMPS● | COMPASS Pathways Plc - American | 1 | 0 | 0 | 1 |
| ADUS | Addus HomeCare Corporation | 0 | 2 | 4 | 6 |
| ARDT | Ardent Health, Inc. | 0 | 2 | 0 | 2 |
| AMN | AMN Healthcare Services Inc | 0 | 0 | 1 | 1 |
| AGL | agilon health, inc. | 0 | 0 | 0 | 0 |
Concentration counts reflect items disclosed in each peer’s most recent 10-K; disclosed-size classification uses TrendMatrix’s internal 10-K extraction taxonomy.