cretostimogene
“10-K Item 1A: 'We currently depend entirely on the success of cretostimogene, which is our only product candidate'”
Updated
The most significant concentration CG Oncology discloses is cretostimogene, classified HIGH by disclosed size. Below: the full set from the latest 10-K — verbatim quotes, filing references, and a synthesis of what these exposures mean together.
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Source: CG Oncology’s SEC Form 10-K filed — view the filing on SEC EDGAR ↗
Each card carries a disclosed-size chip (HIGH / MEDIUM / LOW — how large the exposure is as a share of revenue, not how dangerous it is) and a nature tag: Built-in(the company’s own model, geography, or products) or Outside party (an external customer, supplier, or distributor it relies on).
“10-K Item 1A: 'We currently depend entirely on the success of cretostimogene, which is our only product candidate'”
“10-K Item 1A: 'We rely on Biovire and third parties for the manufacture and shipping of cretostimogene for clinical development'”
The company's disclosed concentration profile is that of a single-asset clinical-stage oncology company, with the added dimension of a sole manufacturing dependency layered on top. The company depends entirely on the success of cretostimogene, its only product candidate — a high-share, mixed-character concentration that is both structurally inherent to its stage of development and a genuine dependency in the sense that there is no commercial product to generate revenue while cretostimogene is in development. The absence of any other asset in the commercial pipeline means the investment thesis is a binary on this single program. The manufacturing dependency compounds the pipeline risk. The company relies on Biovire and third parties for the manufacture and shipping of cretostimogene for clinical development — a high-share dependency concentration. Without in-house manufacturing capability, any disruption to Biovire's operations, supply chain, or its relationship with the company could delay or halt clinical supply, which in turn would affect the clinical timeline for the sole asset. These two exposures are not independent: a manufacturing disruption directly threatens the single program on which the entire company's value rests. Investors should monitor both the clinical read-outs for cretostimogene and the continuity of the manufacturing relationship with Biovire as the two interlinked concentration risks that dominate this profile.
For the engine’s reasoning on CGON’s current verdict — including which dimensions drove the score — see the per-dimension breakdown.
| Symbol | Name | HIGH | MEDIUM | LOW | Total |
|---|---|---|---|---|---|
| ACAD | ACADIA Pharmaceuticals Inc. | 2 | 0 | 0 | 2 |
| CGON● | CG Oncology, Inc. | 2 | 0 | 0 | 2 |
| ACLX | Arcellx, Inc. | 1 | 1 | 0 | 2 |
| AGIO | Agios Pharmaceuticals, Inc. | 1 | 0 | 0 | 1 |
| ALMS | Alumis Inc. | 1 | 0 | 0 | 1 |
| ADMA | ADMA Biologics Inc | 0 | 1 | 0 | 1 |
Concentration counts reflect items disclosed in each peer’s most recent 10-K; disclosed-size classification uses TrendMatrix’s internal 10-K extraction taxonomy.