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DNLIDenali Therapeutics Inc.Sell5.4·$22.31-2.17%

Denali Therapeutics (DNLI) Q2 2026 earnings — TrendMatrix coverage

MISS · WIDER LOSS-29.9% vs estimateEPS -$0.68 vs -$0.52 estCurrent verdict Sell 5.4/10

Reported

Model-generated analysis — not investment advice. Not a registered investment advisor. Past performance does not guarantee future results. How we score · Full disclosure

Event detail · Q2 2026

Key numbers

Reported EPS
-$0.68
Estimate
-$0.52
Surprise
-29.9%
Revenue (period 2026-06-30)
$3.6M
Score today
5.4/10

Revenue source: mixed.

Report record · Q2 2026

How the report landed

Denali Therapeutics (DNLI) reported a wider loss than forecast — diluted EPS of -$0.68 against the -$0.52 estimate (a 29.9% shortfall).

Current read · as of 2026-09-04

Where TrendMatrix's rating stands now

TrendMatrix currently rates DNLI Sell at 5.4/10; no pre/post engine snapshot brackets this report.

3 of the last 4 quarters beat the estimate; this quarter's -29.9% surprise compares with a -9.5% four-quarter average. Next scheduled report: 2026-11-05.

What argues against it

  • Concentration risk — Pipeline: tividenofusp alfa
  • Quality below floor (1.8 < 4.0)
  • Momentum score 2.6/10 — below 4.5 minimum

This section and the ones below it reflect TrendMatrix’s latest engine read — they update after the report date and are not frozen to it.

Current engine read

The levels TrendMatrix's engine tracks

Current price
$22.31
Price target
$32.18
Stop
$21.48
Upside to target
+44.2%
Reward-to-risk
5.5:1

Model outputs from TrendMatrix’s engine as of 2026-09-04 — shown for context, not personalized investment advice.

Healthcare context

DNLI at TrendMatrix's latest read

Healthcare earnings trade on pipeline and payer dynamics as much as the quarter itself; a beat or miss is weighed against trial and reimbursement news.

Industry
Biotechnology
Market cap
$3.64B
P/E (fwd)
-9.4
52-week range
$12.58$27.30
Off 52-week high
18.3%
RSI (14)
34
Volume vs avg
0.41×
Score today
5.4/10

Earnings figures are sourced from TrendMatrix’s pipeline (EPS: existing earnings extraction; revenue: SEC XBRL company facts where available, yfinance-provisional otherwise). Not a buy/sell rating, a price target, or investment advice — see the current verdict on the stock’s main page for TrendMatrix’s live read.

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